Sentences with phrase «potential as a cancer therapy»

The scientists have licensed Rapalink to Kura Oncology, which will continue to evaluate its potential as a cancer therapy.

Not exact matches

Drugs that target VCP are already being developed as potential therapies for cancer.

However, in the wake of fatalities from gene therapy and other technologies, as well as the potential for cancers associated with stem cell transplants, governments are understandably nervous about safety issues — not to mention the ethical maze of tinkering with fledgling life.

Now a team of researchers from Central South University in China have demonstrated that a technique known as photoacoustic imaging, which is already under investigation for detecting skin or breast cancers and for monitoring therapy, also has the potential to be a new, faster, cheaper and non-invasive method to detect, diagnose and stage cervical cancer with high accuracy.

Importantly this article suggests that geranylgeraniol deserves further study as a potential therapy for human prostate cancer.»

«Gene defect as a potential gateway for targeted prostate cancer therapy.»

«A retrospective analysis of the CHD1 gene in these samples may reveal the potential utility of CHD1 as a biomarker for improved prostate cancer patient stratification and targeted therapy with PARP inhibitors,» notes Johnsen.

The process, which located a genetic site for the most common form of prostate cancer, has potential for developing precision therapy for other cancers, such as breast, brain and colorectal, say researchers at The University of Texas MD Anderson Cancer Ccancer, has potential for developing precision therapy for other cancers, such as breast, brain and colorectal, say researchers at The University of Texas MD Anderson Cancer CCancer Center.

«People have been targeting telomerase as a potential cancer therapy for a long time,» he says, noting that anti-telomerase drugs are in phase II clinical trials against several cancers.

During the past decade, some cancer research has highlighted the potential therapies found in plants, including chemicals found in foods such as turmeric, apple peels and green tea.

DFMO is being investigated in human clinical trials to treat some types of cancer, but it hasn't been tested as a potential therapy for Alzheimer's.

In efforts to enhance pre-clinical drug testing, Thomas Gaddy of the University of Southern California, Los Angeles, and colleagues in the research group of Professor Stacey Finley investigated a potential predictive biomarker for a type of cancer drug known as anti-angiogenic therapy.

Notably, multiple Notch inhibitors are in various stages of clinical development as potential cancer therapies.

Because the proteins can be engineered to suppress tumor growth they have emerged as a potential cancer therapy.

«RNAi therapies are a unique approach to cancer treatment as they have the potential to «turn off» the genes» coding for proteins involved in cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.&cancer treatment as they have the potential to «turn off» the genes» coding for proteins involved in cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.&cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.&Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression of specific proteins involved in tumor growth.&cancer cell to block the expression of specific proteins involved in tumor growth.»

Interpretation of genome sequencing data is a significant challenge because of the volume of genomic data to sift through, as well as the large, growing body of research on molecular drivers of cancer and potential targeted therapies.

The results in dogs allowed the scientists to advance PAC - 1 as a potential therapy against human cancers.

«We have built a team that is passionately focused on the potential of cell - based therapies to prevent, treat and cure life - threatening and debilitating diseases such as cardiac disease, cancer and macular degeneration,» said Richard Jove, Ph.D., director, NSU Cell Therapy Institute; chair and professor, Department of Biomedical Sciences, NSU M.D. College; and WSCS co-chair.

As MD Anderson moves toward molecular characterization of the cancers of all our patients, allowing their optimal assignments to promising new targeted therapies and potential identification of biomarkers of response and resistance, the department's mission includes thematic translational research and preclinical molecular pathology research.

Potential cardioprotection was based on generally supportive data on lipid levels in intermediate outcome clinical trials, trials in nonhuman primates, and a large body of observational studies suggesting a 40 % to 50 % reduction in risk among users of either estrogen alone or, less frequently, combined estrogen and progestin.2 - 5 Hip fracture was designated as a secondary outcome, supported by observational data as well as clinical trials showing benefit for bone mineral density.6, 7 Invasive breast cancer was designated as a primary adverse outcome based on observational data.3, 8 Additional clinical outcomes chosen as secondary outcomes that may plausibly be affected by hormone therapy include other cardiovascular diseases; endometrial, colorectal, and other cancers; and other fractures.3, 6,9

These studies support the idea that nutrient transporters can be exploited as potential drug targets for cancer therapy and usher us into a new era of novel cancer therapeutics beyond kinase inhibitors and growth factor receptor blockers.

«If the pilot trial is successful, we plan to pursue a larger trial to explore this strategy's potential as a straightforward and cost - effective way to improve the existing therapy for AML and MDS,» said Peter Jones, Ph.D., D.Sc., co-senior author of the PNAS study, chief scientific officer at Van Andel Research Institute (VARI) and co-leader of the Van Andel Research Institute — Stand Up To Cancer (VARI — SU2C) Epigenetics Dream Team.

GSK3β, the first neighbour of β - catenin is a central, highly multi-functional protein known as a key protein difficult to inhibit without causing side effects and toxicity.41 In glioblastoma and NSCLC cancer, previous studies found that the decreased level of FRAT1 influences the GSK3β activity to phosphorylate β - catenin and by that, inhibit the WNT pathway.39, 40 The role of FRAT1 in colon cancer is less known but based on its function in other cancer types and its special influencing position in colon cancer signalling, we point out its relevance as a potential target in colon cancer therapy (Fig. 3d).

Nutritional ketosis has received a lot of attention by cancer researchers in recent years, and many studies show it has great potential not just as a form of cancer prevention but also treatment — in combination with other treatments such as chemotherapy and radiation.16 Research is looking at whether non-toxic metabolic therapies and drug cocktails may be just as effective, with less toxicity.

The past century has unveiled a plethora of preclinical data that has suggested the potential of a ketogenic diet as an aid in cancer treatment.7, 8 The benefits of a ketogenic diet, and dietary manipulation in general, may be a potent adjunct to current cancer treatments by synergistically working with chemotherapy and radiation therapy to starve cancer cells, leaving them more susceptible to damage from these treatments.7 - 10

It has been proposed as a potential therapy option within cancer as this population group are known to have difficulties with eating especially when going through active treatment.

There are many other potential causes of cataracts in dogs, such as birth defects, infection, radiation (usually from prolonged radiation therapy for cancer of the head), etc. but discussion of these causes is beyond the scope of this review article.

In most cases where surgical options and radiation therapy have proven limited, chemotherapy has emerged as the only option to eradicate cancer despite the potential for severe adverse side effects.