They successfully converted mature mouse skin cells into what they called induced pluripotent stem (iPS) cells that had the same wide - open
potential as embryonic stem cells — which the researchers showed by turning their iPS cells into nerve and connective tissue cells.
Not exact matches
In this way they act like
embryonic stem cells and share their revolutionary therapeutic
potential — and
as such, they could eliminate the need for using and then destroying human embryos.
miR - 34a - deficient
embryonic stem cell culture is enriched with
cells with expanded developmental
potential as shown by their strong MuERV - L induction (red).
Embryonic stem cells have the
potential to develop into any
cell type in the body, and many scientists would like to discover how to use them to treat intractable diseases such
as diabetes or Parkinson's disease.
Other
potential uses of
embryonic stem cells include investigation of early human development, study of genetic disease and
as in vitro systems for toxicology testing.
The
potential of iPS
cells to help treat everything from damaged heart tissue to Parkinson's disease, has prompted intensive research that has looked into the use of skin fibroblast
cells as an alternative to controversial
embryonic stem cells.
«This discovery will advance our understanding of
stem cell epigenetics and chromatin structures, provide
potential mechanisms on maintaining the hallmark properties of ES
cells, and help researchers with the rich source of information to better understand some of the unique features — such
as self - renewal and pluripotency — of human
embryonic stem cells,» said Ng Huck Hui, Ph.D., senior group leader at GIS and a member of the Singapore team that conducted this research.
He also discussed his current viewpoint on whether induced pluripotent
stem cells (iPS)-- which are derived from adult
cells — will have the same
potential therapeutic utility
as human
embryonic stem cells.
The challenge takes on even more urgency with recent developments, including a federal administration now more open to exploring the
potential of
stem cells, the recent FDA approval of a human trial involving
embryonic stem cells,
as well
as the reported case of a young boy who developed a brain tumor four years after receiving a
stem -
cell treatment for a rare genetic disorder.
Alternatively,
embryonic stem (ES)
cells have emerged
as a
potential source of less immunogenic hematopoietic progenitor
cells (HPCs).
As you know, embryonic stem cells have the potential to be used to treat and better understand deadly and disabling diseases and conditions that affect more than 100 million Americans, such as cancer, heart disease, diabetes, Parkinson's, Alzheimer's, multiple sclerosis, spinal cord injury, and many other
As you know,
embryonic stem cells have the
potential to be used to treat and better understand deadly and disabling diseases and conditions that affect more than 100 million Americans, such
as cancer, heart disease, diabetes, Parkinson's, Alzheimer's, multiple sclerosis, spinal cord injury, and many other
as cancer, heart disease, diabetes, Parkinson's, Alzheimer's, multiple sclerosis, spinal cord injury, and many others.