Sentences with phrase «potential bone fractures»

Not exact matches

As a result, periods missed due to malnutrition suggest low estrogen, and therefore a potential for poor bone growth, which, in turn, compromises bones and can lead to early hip fractures in a woman's 30s and to osteoporosis.

The results, appearing in Nature Communications, offer potential treatment targets for this rare disease, provide important clues about bone development, and may lead to insights about fracture healing and osteoporosis.

Potential cardioprotection was based on generally supportive data on lipid levels in intermediate outcome clinical trials, trials in nonhuman primates, and a large body of observational studies suggesting a 40 % to 50 % reduction in risk among users of either estrogen alone or, less frequently, combined estrogen and progestin.2 - 5 Hip fracture was designated as a secondary outcome, supported by observational data as well as clinical trials showing benefit for bone mineral density.6, 7 Invasive breast cancer was designated as a primary adverse outcome based on observational data.3, 8 Additional clinical outcomes chosen as secondary outcomes that may plausibly be affected by hormone therapy include other cardiovascular diseases; endometrial, colorectal, and other cancers; and other fractures.3, 6,9

Regardless of whether a fracture is displaced, non-displaced, open, or closed, a broken bone may result in considerable pain, discomfort, and the potential for permanent physical impairment.

Furthermore, a new safety warning issued by the FDA cautions consumers and medical professionals of a potential risk of bone fractures in patients using Invokana.