Sentences with phrase «potential changes in the number»

In this break between Slams, I was wondering if it might be a good moment to ask about the potential changes in the number of seeds at Slams and the impact this might have on the remainder of the tennis season.

The study assessed the potential changes in number of eggs laid in a nest, incubation start date and nest survival for 2050 and 2080.

Not exact matches

Actual operational and financial results of SkyWest, SkyWest Airlines and ExpressJet will likely also vary, and may vary materially, from those anticipated, estimated, projected or expected for a number of other reasons, including, in addition to those identified above: the challenges and costs of integrating operations and realizing anticipated synergies and other benefits from the acquisition of ExpressJet; the challenges of competing successfully in a highly competitive and rapidly changing industry; developments associated with fluctuations in the economy and the demand for air travel; the financial stability of SkyWest's major partners and any potential impact of their financial condition on the operations of SkyWest, SkyWest Airlines, or ExpressJet; fluctuations in flight schedules, which are determined by the major partners for whom SkyWest's operating airlines conduct flight operations; variations in market and economic conditions; significant aircraft lease and debt commitments; residual aircraft values and related impairment charges; labor relations and costs; the impact of global instability; rapidly fluctuating fuel costs, and potential fuel shortages; the impact of weather - related or other natural disasters on air travel and airline costs; aircraft deliveries; the ability to attract and retain qualified pilots and other unanticipated factors.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

This is an incredibly difficult question to answer for a variety of reasons, most importantly because over the years our once vaunted «beautiful» style of play has become a shadow of it's former self, only to be replaced by a less than stellar «plug and play» mentality where players play out of position and adjustments / substitutions are rarely forthcoming before the 75th minute... if you look at our current players, very few would make sense in the traditional Wengerian system... at present, we don't have the personnel to move the ball quickly from deep - lying position, efficient one touch midfielders that can make the necessary through balls or the disciplined and pacey forwards to stretch defences into wide positions, without the aid of the backs coming up into the final 3rd, so that we can attack the defensive lanes in the same clinical fashion we did years ago... on this current squad, we have only 1 central defender on staf, Mustafi, who seems to have any prowess in the offensive zone or who can even pass two zones through so that we can advance play quickly out of our own end (I have seen some inklings that suggest Holding might have some offensive qualities but too early to tell)... unfortunately Mustafi has a tendency to get himself in trouble when he gets overly aggressive on the ball... from our backs out wide, we've seen pace from the likes of Bellerin and Gibbs and the spirited albeit offensively stunted play of Monreal, but none of these players possess the skill - set required in the offensive zone for the new Wenger scheme which requires deft touches, timely runs to the baseline and consistent crossing, especially when Giroud was playing and his ratio of scored goals per clear chances was relatively low (better last year though)... obviously I like Bellerin's future prospects, as you can't teach pace, but I do worry that he regressed last season, which was obvious to Wenger because there was no way he would have used Ox as the right side wing - back so often knowing that Barcelona could come calling in the off - season, if he thought otherwise... as for our midfielders, not a single one, minus the more confident Xhaka I watched played for the Swiss national team a couple years ago, who truly makes sense under the traditional Wenger model... Ramsey holds onto the ball too long, gives the ball away cheaply far too often and abandons his defensive responsibilities on a regular basis (doesn't score enough recently to justify): that being said, I've always thought he does possess a little something special, unfortunately he thinks so too... Xhaka is a little too slow to ever boss the midfield and he tends to telegraph his one true strength, his long ball play: although I must admit he did get a bit better during some points in the latter part of last season... it always made me wonder why whenever he played with Coq Wenger always seemed to play Francis in a more advanced role on the pitch... as for Coq, he is way too reckless at the wrong times and has exhibited little offensive prowess yet finds himself in and around the box far too often... let's face it Wenger was ready to throw him in the trash heap when injuries forced him to use Francis and then he had the nerve to act like this was all part of a bigger Wenger constructed plan... he like Ramsey, Xhaka and Elneny don't offer the skills necessary to satisfy the quick transitory nature of our old offensive scheme or the stout defensive mindset needed to protect the defensive zone so that our offensive players can remain aggressive in the final third... on the front end, we have Ozil, a player of immense skill but stunted by his physical demeanor that tends to offend, the fact that he's been played out of position far too many times since arriving and that the players in front of him, minus Sanchez, make little to no sense considering what he has to offer (especially Giroud); just think about the quick counter-attack offence in Real or the space and protection he receives in the German National team's midfield, where teams couldn't afford to focus too heavily on one individual... this player was a passing «specialist» long before he arrived in North London, so only an arrogant or ignorant individual would try to reinvent the wheel and / or not surround such a talent with the necessary components... in regards to Ox, Walcott and Welbeck, although they all possess serious talents I see them in large part as headless chickens who are on the injury table too much, lack the necessary first - touch and / or lack the finishing flair to warrant their inclusion in a regular starting eleven; I would say that, of the 3, Ox showed the most upside once we went to a back 3, but even he became a bit too consumed by his pending contract talks before the season ended and that concerned me a bit... if I had to choose one of those 3 players to stay on it would be Ox due to his potential as a plausible alternative to Bellerin in that wing - back position should we continue to use that formation... in Sanchez, we get one of the most committed skill players we've seen on this squad for some years but that could all change soon, if it hasn't already of course... strangely enough, even he doesn't make sense given the constructs of the original Wenger offensive model because he holds onto the ball too long and he will give the ball up a little too often in the offensive zone... a fact that is largely forgotten due to his infectious energy and the fact that the numbers he has achieved seem to justify the means... finally, and in many ways most crucially, Giroud, there is nothing about this team or the offensive system that Wenger has traditionally employed that would even suggest such a player would make sense as a starter... too slow, too inefficient and way too easily dispossessed... once again, I think he has some special skills and, at times, has showed some world - class qualities but he's lack of mobility is an albatross around the necks of our offence... so when you ask who would be our best starting 11, I don't have a clue because of the 5 or 6 players that truly deserve a place in this side, 1 just arrived, 3 aren't under contract beyond 2018 and the other was just sold to Juve... man, this is theraputic because following this team is like an addiction to heroin without the benefits

Drivers have to keep the pace up and manage tyre wear and fuel use across a race whilst also needing to adapt to potential strategy changes (of which there are many in IndyCar, thanks to the number of caution periods).

The New York state budget might end up in court under some potential scenarios, as state lawmakers are discussing possible legal action against Gov. Andrew Cuomo's budget, and his proposal to link a number of unrelated items, like ethics reform and education changes, to the spending plan.

Consequently, «metformin is being studied in various solid tumors,» Karmalis says, «and has the potential to change treatment paradigms for a number of cancer types,»

«Knowing that immune cytokines can change pigment production in melanocytes, while also knowing that chronic inflammation has the potential to increase the number of melanocytes, has clear implications for the design of future therapies to address a set of common skin disorders,» says Dr. Krueger, director of Milstein Research Program and D. Martin Carter Professor in Clinical Investigation.

Oregon and Washington are the number one and two softwood - producing states in the nation, respectively; 20 these two states plus Idaho produce more than $ 11 billion in primary wood product sales.21 Our review of existing research suggests the Northwest's forests will experience significant potential impacts from climate change, in particular from wildfire — due to both increased drought and to wood damage from pests surviving warmer winters.

Simply by changing the number of modules, Climeworks expects their DAC technology can be freely scaled to meet the demands of any sustainable industrial application, and that it could have a carbon removal potential that is relevant for achieving climate targets agreed upon in the Paris Agreement.

The change in sex ratio of snow leopards in Tost was accompanied by a potential decline in the number of cubs per female over the study period as the female population increased.

It's really a no - win scenario for this remake (already infamous for its delays in production after deciding to change the invading country from China to North Korea because, well, China has over 40 times the people of North Korea, which, by the numbers, is more potential tickets to be sold worldwide and a far less plausible setup).

Researchers suggested a number of potential improvements to current leadership development programmes, such as adapting the content to keep up with the evolving demands of leadership roles in education and the «fast - paced» changes to national policy and the curriculum.

We attempted to mitigate potential accuracy issues with the first two metrics, which is based on 2007 data — the most current time period available — by using the growth statistic measuring the change in the number of restaurants from 2007 to 2009, a particular tough (and telling) time for restaurants.

However, changes to corporate employee benefits and government entitlements have the potential to further increase the number of older Canadians living in poverty.

Animal Welfare groups and volunteers are attempting to change that point of view by educating owners and potential owners about the lifelong commitment involved in adopting an animal, how to be a responsible pet owner, about the large number of adoptable animals available at shelters, and about the often poor condition of pet shop pets.

What are you doing to assist the dog in toilet training it's all well and good to rescue large number of dogs but if you don't try and change or alter the behaviour why are so choosy in with your potential adopters, really doesn't make too much sense.

«This is because the reproductive potential of female feral cats within and around the study sites is unlikely to have been large enough over a 13 - month period to produce the rapid changes in numbers that we observed.»

- the game's shading mechanism has changed, which allows for increased gear texture quality - all graphical aspects and programming mechanisms have been built up from scratch for this sequel - maximum resolution is 1080p in TV mode - a bigger focus for Nintendo was the 60 frames per second - occasionally the resolution will be scaled down when there is too much ink displaying on the screen - Nintendo reduced the CPU load and refined the way to use CPU power effectively to maintain 60 fps in all matches - weapons were tweaked to let players be more creative by thinking about unique weapon characteristics and their best uses - weapons are designed to be effective when they are used during the right occasion - Special weapons are stronger than the original ones when used in the right situation, but weaker otherwise - the damage and effect of slowing down your movement when you step in the opponent's ink are reduced from original - you can jump up in rank if you're good enough, but only up until S - you can't jump up from C, B or A to S + - when you win battles in Ranked mode, the Ranked meter fills and your rank goes up when its fully filled - when you lose a battle, the gauge does not decrease, but the meter starts to crack - once the meter reaches its limit, it breaks - when the meter breaks, you have to start over again from the beginning or from a lower rank - highest rank is still S +, but if you fill up the Ranked meter, you get numbers after the alphabet such as «S +1», «S +2» and so on - maximum number is «S +50», but this number will not be displayed to your opponent - you are the only one to see it, and you can check it on your own status screen - Ranked Power is calculated by an algorithm to measure how strong each player is with minuteness - this will determine if a player's rank is worthy of receiving a big jump (like from «C» to «A»)- Ranked Power has no relation to your splat rate, and is more tied into to how well you lead your team to victory - you won't drop off more than one rank even if you play poorly - stage rotation time was changed to two hours - this was done because the devs expected people to play for an hour or so, but they found people play much longer - with Salmon Run, Nintendo considered how to implement a co-op oriented mode in a player - versus - player type of game - the devs will monitor how users are playing this mode to see if there's some tweaks they can throw in - more Salmon Run maps will be added in the future, but Nintendo wouldn't comment on adding more enemy types to the mode - rewards are changed each time Salmon Run is played - you can obtain rewards when playing locally, but not gear - originally Nintendo had an idea for this mode, but had no background setting, enemy designs, etc. - Inoue suggested that it should be salmon - themed - when Nintendo hosted the Splatfest that pit Callie against Marie, the development of Splatoon 2 had started - the devs had already decided to have the result reflected in the sequel - they even had an idea to announce the Splatfest with a phrase «Your choice will change the next Splatoon» - the timing to announce a sequel wasn't right, so they decided against this - they eventually released a series of short stories about the Squid Sisters to show how the Splatfest affected the sequel's story - Nintendo wouldn't say if Marina is an Octoling, and noted that Inklings are not paying attention to this too much - Inklings don't care about appearances, as long as everyone is doing something fresh - the Squid Sisters had composers who produced their songs, but Off the Hook are composing their music by themselves - Pearl is genius artist, but she couldn't find a right partner because she's a bit too edgy - she eventually found Marina as a partner though, and their chemistry is sparkling right now - Nintendo is planning a year of content updates for Splatoon 2 - when finished, the quantity of stages will be more than the original - some of the additional stages are totally new and some will be arranged stages from the first game - not all original stages will return and they are choosing stages based on the potential for them to be improved - Brella is shotgun-esque weapon, so the ink hits your opponent more if you are closer - it can shield damage when you open it, but the amount of damage has a limit and once it reaches it, it breaks - you can shoot ink, but you can't use the shield feature when it breaks - the shield won't prevent your allies ink - there are more new weapon categories which haven't been revealed yet - there are no other ranked modes outside of the three current options - the future holds any sort of possibility, but the devs didn't get specific about adding more content like that - for the modes, they adjusted the rule designs so that players will experience the more interesting aspects

The IPCC range, on the other hand, encompasses the overall uncertainty across a very large number of studies, using different methods all with their own potential biases and problems (e.g., resulting from biases in proxy data used as constraints on past temperature changes, etc.) There is a number of single studies on climate sensitivity that have statistical uncertainties as small as Cox et al., yet different best estimates — some higher than the classic 3 °C, some lower.

The number of species projected to survive in these refugia (Fig. 4, E through H) depends critically on the ability to disperse, highlighting the importance of landscape connectivity and potential restoration in the face of increasing urbanization, land use change, and disturbance.

With an increasing number of people living close to the coast, deep ocean swell generation, and its potential modifications as a consequence of climate change, is clearly an issue that needs attention, alongside the more intensively studied topics of changes in mean sea level and storm surges.

In recent years, a number of climate change commentators, non-governmental organizations, and intergovernmental organizations have discussed the potential need for so - called «negative greenhouse gas emissions» strategies.

There are a number of potential structures for formalized international cooperation on climate change mitigation, referred to in the text as policy «architectures».

The finger pushing the balance below can be likened to changes in greenhouse gases or any of a number of potential control variables.

In a report looking at the potential impacts of of rising greenhouse gas emissions, they discussed a number of ways scientists could measure the world's efforts to limit climate change.

You go from 727 stations to 160, an ~ 80 % reduction in N. That's an 80 % reduction in the number of trends and therefore an enormous potential change where the distribution bounds lie.

As well as advising partners on the risks and opportunities associated with climate change, he has authored Getting to Zero: Defining Corporate Carbon Neutrality, which explores a number of the claims of carbon or climate neutrality that have been made so far and makes a series of recommendations about what should lie behind any such declaration, and Making Sense of the Low Carbon Economy, which provides an accessible overview of the drivers behind the low carbon economy and explores the potential implications for business in the UK.

«Working with data pertaining to 7450 cardiovascular - related deaths that occurred within Budapest, Hungary, between 1995 and 2004 — where the deceased were «medico - legally autopsied» — Toro et al. looked for potential relationships between daily maximum, minimum and mean temperature, air humidity, air pressure, wind speed, global radiation and daily numbers of the heart - related deaths... scientists report and restate their primary finding numerous times throughout their paper, writing that (1) «both the maximum and the minimum daily temperatures tend to be lower when more death cases occur in a day,» (2) «on the days with four or more death cases, the daily maximum and minimum temperatures tend to be lower than on days without any cardiovascular death events,» (3) «the largest frequency of cardiovascular death cases was detected in cold and cooling weather conditions,» (4) «we found a significant negative relationship between temperature and cardiovascular mortality,» (5) «the analysis of 6 - hour change of air pressure suggests that more acute or chronic vascular death cases occur during increasing air pressure conditions (implying cold weather fronts),» (6) «we found a high frequency of cardiovascular death in cold weather,» (7) «a significant negative relationship was detected between daily maximum [and] minimum temperature [s] and the number of sudden cardiovascular death cases,» and (8) «a significant negative correlation was detected between daily mean temperature and cardiovascular mortality.»

How much does potential surface area for CO2 absorption vary with a one percent change in the number and nature of water droplets in the atmosphere?

Prudential Staff Pensions Ltd v Prudential Assurance Co Ltd [2011] PLR 239 — Proceedings for directions on a large number of issues (including issues of estoppel and potential breach of the employer's duty of good faith) following a change by Prudential in its long - established policy of granting discretionary RPI linked increases to pensions in payment;

In order to invoke the imagination, I have also included two case studies which explore first hand the potential impacts of climate change on a number of human rights of the Indigenous peoples, particularly those living on the Torres Strait Islands and the Indigenous nations of the Murray - Darling Basin.

Developmental change occurs as a result of reciprocal interactions between the intrinsic characteristics of a child and his environmental context, making the child both the producer and product of the environment.50 Behavioural inhibition may initiate a child in one of a number of directions, and the targeted outcome can result from a host of predisposing pathways.10 Research must therefore account for a number of potential moderating factors that can come into play at various points throughout development.

Drawing on interpersonal neurobiology, affect regulation research, and a number of theoretical orientations, this book will help therapists discover the potential for resilience in clients and help them cultivate it for lasting change.

The government wants to see double the number of children placed with their new adoptive families at the earliest possible point, halving the time they are waiting in care for the full process to be completed, and intends to change regulations around the assessment of potential special guardians.

If renovating in order to sell, you must plan for changes that will meet the needs of a majority of potential buyers and ensure that the modifications are suitably up to date and will appeal to the maximum number of people.