Sentences with phrase «potential changes to the environment»

During this consult we will discuss the problems you're having, the possible reasons they are occurring, potential changes to the environment that could help, and any training that may resolve the problem.

Not exact matches

If we can take a page out of my grandfather's book and change the way we recruit entrepreneurs, then we can create an environment where everyone with the potential to create the next big idea will have what they need to succeed.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

32:19 Shel's ability to see possibilities and respond to them in ways that help businesses get ahead of potential issues, take action, and create solutions that help the environment and create social change.

This Thursday, Canada's Environment and Climate Change Minister Catherine McKenna published an open letter to B.C. Environment Minister George Heyman outlining the steps that Ottawa has taken to prepare for a potential spill involving the proposed pipeline, and offering scientific collaboration with the province to ensure its concerns are addressed.

This Thursday, Canada's Environment and Climate Change Minister Catherine McKenna published an open letter to B.C. Environment Minister George Heyman outlining the steps that Ottawa has taken to prepare for a potential spill involving the proposed pipeline, and offering...

Of course it would be silly to suggest that winning any game, cup or otherwise, isn't good for the club, but let's remember just how problematic FA Cup success has been for this club... I'm certainly not going to suggest I didn't enjoy seeing Arsenal win, I'm a fan of this club first and foremost, but how bad are things when you find yourself secretly wishing that your own team lost so that just maybe real change would finally come... I resent this team for even making me feel such thoughts and it's going to take a lot of effort on their part to earn my trust again... this club has treated the fans so poorly that it has created an incredibly fragile and toxic environment, so much so that a «what have you done for me lately» mentality has emerged... fans rise and fall depending on the results of each game because we don't have faith in those in charge to make the necessary changes to personnel and tactics... each time we win many fans attack any dissenting voices and make unrealistic claims about the players, the manager and the potential for unprecedented success... every time we lose the boo - birds run rampant, calling for heads to roll and predicting the worst... regardless of what side you fall on, it's not your fault, both sides are simply overcompensating for the horrible state of affairs that have been percolating for several years... it's hard to take the long view when those in charge have lied incessantly and refuse to take any responsibilities for their own actions... in the end, we are trapped by the same catch - 22 that ManU faced upon Fergie's exit... less fearful of maintaining the status quo than facing the unknown, which was validated, wrongly or rightly, by witnessing the difficulties they have faced during this transitory period... to be honest, the thing that scares me most is that this team has never prepared whatsoever for this eventuality, which considering our frugal nature and the way we have shunned many of our most revered former players is more than a little disconcerting

As a result, it's a huge shame for a player with Isco's talent not to be fulfilling his potential and getting the best out of himself, as perhaps a change of environment is needed.

Stakeholders» input was integrated into development of A Healthy Start for Minnesota Children: Supporting Opportunities for Life - Long Health, a theory of change that depicts how public understanding, health in all policies, and community innovation lead to 1) safe, stable, nurturing relationships and environments and 2) social and economic security, which in turn will help the state achieve its ultimate outcome — that every Minnesota child, prenatal to age three years, will thrive in their family and community and achieve their full potential regardless of their race, where they live, or their family's income.

«Because of the close proximity of the 137 - unit Ezra Prentice Homes residential housing development to Global's facility, the potential for these proposed changes to have significant adverse impacts on the environment must be fully analyzed,» D.E.C. officials wrote in a letter.

Miner says it's important to have experience in that department with potential changes to the federal regulatory environment by the Trump administration.

Her changes, she said, would help them mitigate any potential harm to the environment.

«The potential for the organisms to evolve in response to a rapidly changing environment is often downplayed, even though very few studies have examined the extent to which species might adapt,» said Michael Logan, who recently received a Ph.D. from Dartmouth College and is now a postdoctoral fellow at the National Science Foundation.

«I believe it would be irresponsible to ignore emerging information about the contribution of carbon dioxide and other greenhouse gases to climate change and the potential harm to our environment and health if we do nothing.»

Stephen Schneider A senior fellow at the Woods Institute for the Environment at Stanford University, Schneider assesses ecological and economic impacts of human - induced climate change to identify potential political and technological solutions.

That can be achieved, Cheryan said, by developing «subcultures» that make girls feel they belong, whether that involves changing classroom décor to create a more welcoming environment or counteracting negative stereotypes about women's abilities by making it clear that everyone has the potential to succeed.

Dr Hauptmann added: «More attention needs to be paid to the potential release of anthropogenic contaminants in this fast - changing environment.

2) The environment may have the potential to trigger molecular changes that pass from generation to generation.

Citizen scientists engaging in their regular work or recreational activities have tremendous potential to observe and record events that may identify important changes in the environment

«We always have breeding as a goal on the horizon, and are continuing to raise fish on land to examine other potential changes that a new environment might induce.»

The recent spate of destructive cyclones and the potential for longer - term changes have indeed created an environment of concern, both to the insurance industry and to the millions of people who have been directly affected («Who will underwrite the hurricane?»

The authors say reefs located in northern Mozambique and the Quirimbas Islands supports two types of refuges and a gradient of environments that create the potential for corals to adapt to climate change.

Some animals change their environment, as the bowerbird does, but many others transform their appearance or behavior to dupe a potential enemy or unsuspecting meal.

«I'm interested in how the environment is changing, how animals respond to those changes, and the potential for acclimatization to those conditions, particularly across generations and in different life stages,» said Putnam, assistant professor in the URI Department of Biological Sciences, who joined the faculty in January.

Scientists of the Helmholtz Centre for Ocean Research Kiel (GEOMAR) conducted a one year CO2 selection experiment using the calcifying microalgae Emiliania huxleyi and uncovered an enormous potential for adaptation to rapidly changing environments in this important phytoplankton species.

Source: Lyman 2010 The reaction of the oceans to climate change are some of the most profound across the entire environment, including disruption of the ocean food chain through chemical changes caused by CO2, the ability of the sea to absorb CO2 being limited by temperature increases, (and the potential to expel sequestered CO2 back into the atmosphere as the water gets hotter), sea - level rise due to thermal expansion, and the amount of water vapour in the atmosphere.

But the researchers found that humans at rest could devote more than a 30 percent of their metabolic activity to heating up or cooling down over the course of the day as their environments changed — a potential workout for some.

This not only creates a net - positive return to the environment, it has great potential to reverse climate change.

I took what originally seemed like an overwhelming change in my work environment and turned it into an opportunity to showcase my true potential and highlight different skills.

The downside is that it may not be agile enough for an environment where goals have the potential to change.

Meyers: Our goals include providing a media venue where people from all walks of life can have their voices heard in a safe, commercial - free, child - friendly environment; promoting positive role models; empowering young people to realize their own potential to effect positive change in the world; bridging the digital divide and continuing to enrich this digital media archive with inspiring stories from around the globe; enlisting support from foundations, grants, and government agencies, corporations, and individuals so that this global learning project can continue to grow and provide a freely - accessible, online multi-media resource to educators and students around the world for decades to come.

The predictability has the potential to make TEL environments ideal for pupils on the autism spectrum who typically experience discomfort at unexpected change and the uncertainty of face - to - face communication.

It's a simple statement attached to a phenomenal value change that has the potential to make working environments so much more pleasant and supportive.

As Porter describes it, the First Word program, on the subject of authors going global, «is just that — a first word, a deep conversation in a newly changing environment that is only beginning to reveal some of its potentials and its pitfalls.»

Such statements reflect the current views of Barnes & Noble with respect to future events, the outcome of which is subject to certain risks, including, among others, the general economic environment and consumer spending patterns, decreased consumer demand for Barnes & Noble's products, low growth or declining sales and net income due to various factors, possible disruptions in Barnes & Noble's computer systems, telephone systems or supply chain, possible risks associated with data privacy, information security and intellectual property, possible work stoppages or increases in labor costs, possible increases in shipping rates or interruptions in shipping service, effects of competition, possible risks that inventory in channels of distribution may be larger than able to be sold, possible risks associated with changes in the strategic direction of the device business, including possible reduction in sales of content, accessories and other merchandise and other adverse financial impacts, possible risk that component parts will be rendered obsolete or otherwise not be able to be effectively utilized in devices to be sold, possible risk that financial and operational forecasts and projections are not achieved, possible risk that returns from consumers or channels of distribution may be greater than estimated, the risk that digital sales growth is less than expectations and the risk that it does not exceed the rate of investment spend, higher - than - anticipated store closing or relocation costs, higher interest rates, the performance of Barnes & Noble's online, digital and other initiatives, the success of Barnes & Noble's strategic investments, unanticipated increases in merchandise, component or occupancy costs, unanticipated adverse litigation results or effects, product and component shortages, the potential adverse impact on the Company's businesses resulting from the Company's prior reviews of strategic alternatives and the potential separation of the Company's businesses, the risk that the transactions with Microsoft and Pearson do not achieve the expected benefits for the parties or impose costs on the Company in excess of what the Company anticipates, including the risk that NOOK Media's applications are not commercially successful or that the expected distribution of those applications is not achieved, risks associated with the international expansion contemplated by the relationship with Microsoft, including that it is not successful or is delayed, the risk that NOOK Media is not able to perform its obligations under the Microsoft and Pearson commercial agreements and the consequences thereof, risks associated with the restatement contained in, the delayed filing of, and the material weakness in internal controls described in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended April 27, 2013, risks associated with the SEC investigation disclosed in the quarterly report on Form 10 - Q for the fiscal quarter ended October 26, 2013, risks associated with the ongoing efforts to rationalize the NOOK business and the expected costs and benefits of such efforts and associated risks and other factors which may be outside of Barnes & Noble's control, including those factors discussed in detail in Item 1A, «Risk Factors,» in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended April 27, 2013, and in Barnes & Noble's other filings made hereafter from time to time with the SEC.

Such statements reflect the current views of Barnes & Noble with respect to future events, the outcome of which is subject to certain risks, including, among others, the effect of the proposed separation of NOOK Media, the general economic environment and consumer spending patterns, decreased consumer demand for Barnes & Noble's products, low growth or declining sales and net income due to various factors, possible disruptions in Barnes & Noble's computer systems, telephone systems or supply chain, possible risks associated with data privacy, information security and intellectual property, possible work stoppages or increases in labor costs, possible increases in shipping rates or interruptions in shipping service, effects of competition, possible risks that inventory in channels of distribution may be larger than able to be sold, possible risks associated with changes in the strategic direction of the device business, including possible reduction in sales of content, accessories and other merchandise and other adverse financial impacts, possible risk that component parts will be rendered obsolete or otherwise not be able to be effectively utilized in devices to be sold, possible risk that financial and operational forecasts and projections are not achieved, possible risk that returns from consumers or channels of distribution may be greater than estimated, the risk that digital sales growth is less than expectations and the risk that it does not exceed the rate of investment spend, higher - than - anticipated store closing or relocation costs, higher interest rates, the performance of Barnes & Noble's online, digital and other initiatives, the success of Barnes & Noble's strategic investments, unanticipated increases in merchandise, component or occupancy costs, unanticipated adverse litigation results or effects, product and component shortages, risks associated with the commercial agreement with Samsung, the potential adverse impact on the Company's businesses resulting from the Company's prior reviews of strategic alternatives and the potential separation of the Company's businesses (including with respect to the timing of the completion thereof), the risk that the transactions with Pearson and Samsung do not achieve the expected benefits for the parties or impose costs on the Company in excess of what the Company anticipates, including the risk that NOOK Media's applications are not commercially successful or that the expected distribution of those applications is not achieved, risks associated with the international expansion previously undertaken, including any risks associated with a reduction of international operations following termination of the Microsoft commercial agreement, the risk that NOOK Media is not able to perform its obligations under the Pearson and Samsung commercial agreements and the consequences thereof, the risks associated with the termination of Microsoft commercial agreement, including potential customer losses, risks associated with the restatement contained in, the delayed filing of, and the material weakness in internal controls described in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended April 27, 2013, risks associated with the SEC investigation disclosed in the quarterly report on Form 10 - Q for the fiscal quarter ended October 26, 2013, risks associated with the ongoing efforts to rationalize the NOOK business and the expected costs and benefits of such efforts and associated risks and other factors which may be outside of Barnes & Noble's control, including those factors discussed in detail in Item 1A, «Risk Factors,» in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended May 3, 2014, and in Barnes & Noble's other filings made hereafter from time to time with the SEC.

Though small caps have lower exposure to the dollar's impact on international sales, this benefit is being trumped by small cap's potential vulnerability to the changing interest rate environment.

The long / short / flat nature of the fund provides the ability for each of the strategies to act independently from one another, providing an additional layer of potential diversification and the ability to respond to changing market and interest rate environments.

I prefer to focus instead on looking at all my positions afresh every day / week, and asking what % holding (if any) should I now own based on the company's business / financial risk, its share price action, its potential fair value upside, the changing micro and macro risk environment, and the relative value of other holdings / buy list stocks.

As with any change to your pet's environment, there is a potential risk of impaction if your pet ingests a significant amount of its bedding.

Help change the face of veterinary medicine by contributing to inclusive work and learning environments where everyone can reach their full potential.

No matter what innate drives a pup has inherited, he will not work to his full potential for an owner he can not trust or respect and he will be stifled in his work if he is not accustomed to changing environment and situations.

About Heartworm Disease According to the American Heartworm Society (AHS), cases of heartworm have been diagnosed in all 50 states and changes to the environment and natural climate conditions, as well as animal movement, have increased the potential for heartworm infection in more areas around the country.

By designing a tool that assesses a dog's intraspecific sociability while measuring changes seen over time, we can provide valuable information to potential adopters, rescues or fosters and evaluate the impact of off leash interaction among conspecifics in a shelter environment.

Breast Cancer & The Environment Research Centers: Sixth Annual Early Environmental Exposures Meeting The Breast Cancer and the Environment Research Centers (BCERC) network is conducting epidemiologic and biologic studies investigating the influence of early environmental exposures on pubertal maturation and mammary gland development and the potential of these developmental changes to alter the risk of breast cancer in later life.

You could enter a room and be smoothly transitioned into a completely different environment or for the layout to change once you leave, it was an interesting idea in the first game but the potential wasn't fully explored.

She observes social and topographical changes in her environment, the complexities that are embedded in these experiences, and how such things as resources, soil, earth, and its potential worth are subjected to regional and cultural scrutiny.

There is an urgent need to scale up financial flows, particularly financial support to developing countries; to create positive incentives for actions; to finance the incremental costs of cleaner and low - carbon technologies; to make more efficient use of funds directed toward climate change; to realize the full potential of appropriate market mechanisms that can provide pricing signals and economic incentives to the private sector; to promote public sector investment; to create enabling environments that promote private investment that is commercially viable; to develop innovative approaches; and to lower costs by creating appropriate incentives for and reducing and eliminating obstacles to technology transfer relevant to both mitigation and adaptation.

Nearly all of the assertions by the Australian blogger in the second chart were inflammatory and untrue, with only thin threads leading to legitimate issues (one being that the Intergovernmental Panel on Climate Change, as noted in a review by the Dutch environment agency, has traditionally focused its summaries on worst - case outcomes and left out potential positive effects or other factors, like population growth, that contribute to climate vulnerability).

The IPCC was launched by the United Nations Environment Programme (UNEP) and the World Meteorological Organization (WMO) in 1988 to «provide the world with a clear scientific view on the current state of knowledge in climate change and its potential environmental and socio - economic impacts.»