With so many of the test chemicals flagged as potential endocrine disruptors — 495 potential TPO inhibitors, 404 potential NIS inhibitors, and 225
potential deiodinase inhibitors, among others — EPA may find that those tests will also take decades to complete.
Not exact matches
For
deiodinase type 1, 225 chemicals, or 12 % of those tested, showed
potential for inhibiting the enzyme (Toxicol.
Although very minor amounts of selenium appear sufficient for adequate activity of
deiodinases, thus limiting the impact of its
potential deficiency on synthesis of thyroid hormones, selenium status appears to have an impact on the development of thyroid pathologies.