Sentences with phrase «potential effects due»

To better plan for potential effects due to climate change, scientists using the North American Breeding Bird Survey and Audubon Christmas Bird Count employed correlative distribution modeling, to assess geographic range shifts for nearly 600 North American bird species during both the breeding and non-breeding seasons under a range of future climate change scenarios through the end of the century.

Not exact matches

There's no question that content is important (although getting less so, due to information saturation), so if you're going to provide content, you must ensure that it's strategic and has the right effect on your current and potential customer base.

These short - term factors include: unclear payrolls data due to weather effects, uncertainty over the leadership of the Fed and comments of a potential 10 percent repatriation tax for U.S. firms, according to Gallo.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Even if they do not have an allergy to the bean, many people chose to limit the amount of soy in their diet due to the potential negative health effects of various estrogen - like chemicals that it contains.

EFSA Limits 3 - MCPD Concentration Levels Due to the growing concern over the potential adverse health effects associated with 3 - monochloropropanediol (3 - MCPD), the European Food Safety Authority (EFSA) has limited concentration levels of this chemical byproduct in certain foods like hydrolyzed vegetable proteins.

The FDA has responded to the panels allegations, «FDA agrees that due to the uncertainties raised in some studies relating to the potential effects of low doses of bisphenol - A that additional research would be valuable.»

Many mothers prefer the nonpharmacological route of treatment due to the risk of infant exposure and potential side effects of the antidepressants.

As a result, courts have found that parental conflict related to divorce is a societal concern because children suffer potential short - term and long - term detrimental economic, emotional, and educational effects during times of family transition due to divorce.

Scientific research has also questioned the potential health effects of a regular soy - based diet on infants due to its estrogen - like effects.

Its focus was the 171 million children globally who do not have the opportunity to reach their full potential due to the physical and mental effects of poor nutrition in the earliest months of life.

Among the label changes is a strengthened warning that breastfeeding is not recommended while using medicines containing codeine or tramadol, because of the potential for serious adverse effects in the infant due to opioid overdose (1).

The U.S. Food and Drug Administration has strengthened the label warning to state that breastfeeding is not recommended while using medicines containing codeine or tramadol because of the potential for serious adverse effects in the infant due to opioid overdose (76).

«This finding shows that these effects aren't just due to more odious criminals advertising their malice through their faces but, rather, suggests that these really are biases that might mislead people independent of any potential kernels of truth,» say Wilson and Rule.

The effects of cocaine on peripheral nerves — due to rapid uptake through the skin and gills — thus appear to override any potential effects on the brain.

In addition, elderly people tend to take more than one drug at the same time, which multiplies the chances of suffering from adverse effects due to potential drug - drug interactions.

After 50 years of being a mainstay cholesterol therapy, niacin should no longer be prescribed for most patients due to potential increased risk of death, dangerous side effects and no benefit in reducing heart attacks and strokes, writes Northwestern Medicine ® preventive cardiologist Donald Lloyd - Jones, M.D., in a New England Journal of Medicine editorial.

Scientists are continuing to research other potential effects of the disaster, such as whether increased incidence of mental retardation is occurring in subsequent generations due to their progenitors» radiation exposure.

The results, the authors conclude, may also have implications for the assessment of potential health effects due to climate change.

However, like most gene transfer approaches a major concern with ZFN technology is the potential for oncogenesis due to off - target effects.

According to one study that looked at eight fuel aridity metrics in the Western U.S. and modeled climate change's effects on them, human - caused climate change accounted for about 55 percent of the observed increases in fuel aridity between 1979 and 2015 (Figure 6), and added an estimated 4.2 million hectares of forest fire area between 1984 and 2015.7 Based on all eight metrics, the Western U.S. experienced an average of 9 additional days per year of high fire potential due to climate change between 2000 and 2015, a 50 percent increase from the baseline of 17 days per year when looking back to 1979.

However, the paper suggests this is due to epigenetic effects and chromatin remodelling, opening up a potential for epigenetic modulators in future treatment of RA.

This would bypass the potential adverse effects of hypoxia on the CSC fraction while limiting tumor progression due to the general vasculature effects.

But they are not recommended for long - term use due to serious potential side effects.

Face steams are not recommended for young children (due to the potential heat of the steam) or pregnant women (due to the potential effects of the herbs) without checking with a medical professional.

Thankfully, one of my girlfriends, Thy N. Le, Pharm.D., pharmacotherapy specialist and program director at the Brooklyn Hospital Center in New York and a mother, began the conversation early on with me about which skin care ingredients to avoid due to their potential teratogenic effects (birth defects).

Angeline - the antibotics are more powerful, but also have the potential to cause more damage due to killing off beneficial bacteria and side effects.

This has potential long - lasting side effects as antibiotics can permanently alter gut bacteria and many types of bacteria are becoming antibiotic resistant due to overuse of these drugs.

Soy has been linked to many issues due to its potential for increase or decreasing estrogen, creating thyroid issues, and its ability to cause toxic side effects.

So due to the potential side effects and the lack of long term weight loss, a Low - Fat Diet would not be the optimal solution for overall health.

Because of the unique ability of Anabolic Steroids to boost muscle mass, it's used in professional, non-competitive, or competitive sports events are considered illegal due to the possibility of serious adverse effect which can also lead to a high potential of abuse.

Cancer prevention Researchers have hypothesized that higher intakes of omega - 3s from either foods or supplements might reduce the risk of cancer due to their anti-inflammatory effects and potential to inhibit cell growth factors [60].

It's a popular supplement among athletes due to its potential for boosting nitric oxide production, but this effect is unreliable due to poor absorption in the intestines.

Overall, the quality of tea is poor due to the high price and potential side effects.

There may be a potential metabolic advantage of the ketogenic diet but it's mostly due to the appetite suppressing effects of low - carb diets: Expert's Insight: Appetite Control and Caloric Intake on Low - carb Ketogenic Diets It takes a few weeks for your body to use mainly ketones and fat - instead of glucose - for energy.

Interactions ANTICHOLINERGIC DRUGS: Theoretically, concomitant use might decrease the effect of drugs with anticholinergic activity, due to the potential cholinergic activity of DMAE.

Since Gingko biloba has potential side effects for some people, due to certain conditions, remember to always consult with your healthcare professional before using this or any nutritional or medicinal supplements.

Is Withania Somnifera contraindicated when using NatureThroid or other hypothyroid - supporting medications due to its potential effect on thyroid hormones?

Due to the potential side effects, this type of diet can promote many unwanted symptoms.

* Duration of a few weeks * An average dose more equivocal to a «loading» phase than a «maintenance phase» * A larger dose for potential responders who lack natural, dietary creatine * A smaller dose for potential non-responders with a significant amount of existing dietary creatine intake * A training protocol that emphasizes all phases of muscular energetics to take advantage of the ATP - CP, glycolytic, and oxidative effects of creatine supplementation (HIIT is ideal for cardiovascular exercise when supplementing creatine, due to the repeated bouts of high intensity work) * A training protocol that incorporates negatives in order to stimulate satellite cell fusion, as per Dr. Hatfield's theory of holistic training * A training protocol that emphasizes repeated bouts of work per the results of creatine studies * A nutrition protocol tailored to reduce post-workout cortisol levels, which would involve a post-workout shake and possible glutamine supplementation * A nutrition protocol that takes advantage of carb - load (super compensation) near the end of the cycle

A crash diet focuses on nutritional restriction (except from water) and not intended to last more than a couple of weeks due to its potential side effects.

2,3,11 Self - repair mechanisms in the intestinal wall are stimulated, enhancing cell division and growth.3, 11 While many people with GERD are hesitant to partake of bitters due to the potential increase in stomach acidity, the combined effect of these actions actually can help this condition by ensuring that the stomach contents are moved downward rather than allowed to reflux back up and out of the stomach.

Spirulina Juice Powder: A blue - green algae that is used due to its mixture of nutrients and potential effects on improving inflammation and infections.

The emotional effects due to the teasing at school is worse than the potential for this rash to cause an infection.

In 2016, the American Association of University Professors issued a highly critical report on OCR's Title IX policies, pointing out that «faculty in disciplines related to gender and sexuality» are particularly «vulnerable to the chilling effect of potential hostile environment charges and are disproportionately affected in their teaching and research due to universities» adoption of overly broad definitions.»

Second, I verify that my analysis shows spillover effects of charters, rather than a potential performance bump due to students switching between district and charter schools in their neighborhoods.

Such statements reflect the current views of Barnes & Noble with respect to future events, the outcome of which is subject to certain risks, including, among others, the general economic environment and consumer spending patterns, decreased consumer demand for Barnes & Noble's products, low growth or declining sales and net income due to various factors, possible disruptions in Barnes & Noble's computer systems, telephone systems or supply chain, possible risks associated with data privacy, information security and intellectual property, possible work stoppages or increases in labor costs, possible increases in shipping rates or interruptions in shipping service, effects of competition, possible risks that inventory in channels of distribution may be larger than able to be sold, possible risks associated with changes in the strategic direction of the device business, including possible reduction in sales of content, accessories and other merchandise and other adverse financial impacts, possible risk that component parts will be rendered obsolete or otherwise not be able to be effectively utilized in devices to be sold, possible risk that financial and operational forecasts and projections are not achieved, possible risk that returns from consumers or channels of distribution may be greater than estimated, the risk that digital sales growth is less than expectations and the risk that it does not exceed the rate of investment spend, higher - than - anticipated store closing or relocation costs, higher interest rates, the performance of Barnes & Noble's online, digital and other initiatives, the success of Barnes & Noble's strategic investments, unanticipated increases in merchandise, component or occupancy costs, unanticipated adverse litigation results or effects, product and component shortages, the potential adverse impact on the Company's businesses resulting from the Company's prior reviews of strategic alternatives and the potential separation of the Company's businesses, the risk that the transactions with Microsoft and Pearson do not achieve the expected benefits for the parties or impose costs on the Company in excess of what the Company anticipates, including the risk that NOOK Media's applications are not commercially successful or that the expected distribution of those applications is not achieved, risks associated with the international expansion contemplated by the relationship with Microsoft, including that it is not successful or is delayed, the risk that NOOK Media is not able to perform its obligations under the Microsoft and Pearson commercial agreements and the consequences thereof, risks associated with the restatement contained in, the delayed filing of, and the material weakness in internal controls described in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended April 27, 2013, risks associated with the SEC investigation disclosed in the quarterly report on Form 10 - Q for the fiscal quarter ended October 26, 2013, risks associated with the ongoing efforts to rationalize the NOOK business and the expected costs and benefits of such efforts and associated risks and other factors which may be outside of Barnes & Noble's control, including those factors discussed in detail in Item 1A, «Risk Factors,» in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended April 27, 2013, and in Barnes & Noble's other filings made hereafter from time to time with the SEC.

Such statements reflect the current views of Barnes & Noble with respect to future events, the outcome of which is subject to certain risks, including, among others, the effect of the proposed separation of NOOK Media, the general economic environment and consumer spending patterns, decreased consumer demand for Barnes & Noble's products, low growth or declining sales and net income due to various factors, possible disruptions in Barnes & Noble's computer systems, telephone systems or supply chain, possible risks associated with data privacy, information security and intellectual property, possible work stoppages or increases in labor costs, possible increases in shipping rates or interruptions in shipping service, effects of competition, possible risks that inventory in channels of distribution may be larger than able to be sold, possible risks associated with changes in the strategic direction of the device business, including possible reduction in sales of content, accessories and other merchandise and other adverse financial impacts, possible risk that component parts will be rendered obsolete or otherwise not be able to be effectively utilized in devices to be sold, possible risk that financial and operational forecasts and projections are not achieved, possible risk that returns from consumers or channels of distribution may be greater than estimated, the risk that digital sales growth is less than expectations and the risk that it does not exceed the rate of investment spend, higher - than - anticipated store closing or relocation costs, higher interest rates, the performance of Barnes & Noble's online, digital and other initiatives, the success of Barnes & Noble's strategic investments, unanticipated increases in merchandise, component or occupancy costs, unanticipated adverse litigation results or effects, product and component shortages, risks associated with the commercial agreement with Samsung, the potential adverse impact on the Company's businesses resulting from the Company's prior reviews of strategic alternatives and the potential separation of the Company's businesses (including with respect to the timing of the completion thereof), the risk that the transactions with Pearson and Samsung do not achieve the expected benefits for the parties or impose costs on the Company in excess of what the Company anticipates, including the risk that NOOK Media's applications are not commercially successful or that the expected distribution of those applications is not achieved, risks associated with the international expansion previously undertaken, including any risks associated with a reduction of international operations following termination of the Microsoft commercial agreement, the risk that NOOK Media is not able to perform its obligations under the Pearson and Samsung commercial agreements and the consequences thereof, the risks associated with the termination of Microsoft commercial agreement, including potential customer losses, risks associated with the restatement contained in, the delayed filing of, and the material weakness in internal controls described in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended April 27, 2013, risks associated with the SEC investigation disclosed in the quarterly report on Form 10 - Q for the fiscal quarter ended October 26, 2013, risks associated with the ongoing efforts to rationalize the NOOK business and the expected costs and benefits of such efforts and associated risks and other factors which may be outside of Barnes & Noble's control, including those factors discussed in detail in Item 1A, «Risk Factors,» in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended May 3, 2014, and in Barnes & Noble's other filings made hereafter from time to time with the SEC.

Such statements reflect the current views of Barnes & Noble with respect to future events, the outcome of which is subject to certain risks, including, among others, the general economic environment and consumer spending patterns, decreased consumer demand for Barnes & Noble's products, low growth or declining sales and net income due to various factors, including store closings, higher - than - anticipated or increasing costs, including with respect to store closings, relocation, occupancy (including in connection with lease renewals) and labor costs, the effects of competition, the risk of insufficient access to financing to implement future business initiatives, risks associated with data privacy and information security, risks associated with Barnes & Noble's supply chain, including possible delays and disruptions and increases in shipping rates, various risks associated with the digital business, including the possible loss of customers, declines in digital content sales, risks and costs associated with ongoing efforts to rationalize the digital business and the digital business not being able to perform its obligations under the Samsung commercial agreement and the consequences thereof, the risk that financial and operational forecasts and projections are not achieved, the performance of Barnes & Noble's initiatives including but not limited to its new store concept and e-commerce initiatives, unanticipated adverse litigation results or effects, potential infringement of Barnes & Noble's intellectual property by third parties or by Barnes & Noble of the intellectual property of third parties, and other factors, including those factors discussed in detail in Item 1A, «Risk Factors,» in Barnes & Noble's Annual Report on Form 10 - K for the fiscal year ended April 30, 2016, and in Barnes & Noble's other filings made hereafter from time to time with the SEC.

The Fund may be subject to a greater risk of rising interests than normally would be the case due to the current period of historically low rates and the effect of potential government fiscal policy initiatives and resulting market reaction to those initiatives.