Sentences with phrase «potential mechanisms involved»

The increased anti-gliadin antibody response and its association with GI symptoms points to a potential mechanism involving immunologic and / or intestinal permeability abnormalities in affected children.»

Not exact matches

The tool is of interest and involves AD operators too in that it suggests three potential mechanisms designed to share the costs of the intervention between the LA and operator for the mutual benefit of all parties involved.

By pairing a receptor that targets neurons with a molecule that degrades the main component of Alzheimer's plaques, the biologists were able to substantially dissolve these plaques in mice brains and human brain tissue, offering a potential mechanism for treating the debilitating disease, as well as other conditions that involve either the brain or the eyes.

He notes that because of the boggling number of potential factors, such as copy number variations, point mutations and epigenetic (inherited mutation) factors involved in autism, it will be important to find common pathways «because the mechanisms interrupting those pathways might be different among individuals.»

This suggests that DNA methylation changes that alter excitability may be a mechanism involved in neuropsychiatric disorders, and that the sites of such changes may offer a potential therapeutic target.

«More studies are needed to uncover the exact mechanisms involved, but we predict that direct treatment with D4A could prolong survival in some patients with metastatic prostate cancer,» said Dr. Sharifi, «Further studies will also help us develop a potential biomarker profile to predict which patients will respond to D4 — abiraterone.»

NIH scientists have discovered a mechanism involved in stabilizing key HIV proteins and thereby concealing sites where some of the most powerful HIV neutralizing antibodies bind, findings with potential implications for HIV vaccine research.

Researchers at the Center for Vascular Research, within the Institute for Basic Science (IBS), have identified a new mechanism involved in the development and progression of glaucoma, and found a potential therapeutic option...

Approximately 50 % of PTCL are unclassifiable and categorized as PTCL, not otherwise specified (PTCL - NOS).1 Using gene expression profiling, PTCL - NOS lymphocytes can be distinguished from normal T lymphocytes, with deregulation of genes involved in apoptosis, proliferation, cell adhesion, and transcription regulation.2 Two subgroups of PTCL - NOS have been identified, which are characterized by high expression of either GATA3 or TBX21 / T - bet transcription factors and downstream target genes.3 However, actionable biomarkers closely related to the pathogenic mechanism need to be further investigated and may become potential therapeutic targets of PTCL - NOS. 4, 5

There are some various proposed mechanisms to explain this that involve the surface energy balance (e.g., less coupling between the ground temperature and lower air temperature over land because of less potential for evaporation), and also lapse rate differences over ocean and land (see Joshi et al 2008, Climate Dynamics), as well as vegetation or cloud changes.

Despite this generally well - accepted idea for how high eye pressure may affect RGC axons, scientists still do not understand the injury mechanisms involved in sufficient detail to begin identifying potential therapeutic targets.

The findings in the current study help refine our knowledge of some of the important molecular mechanisms involved in Group 3 medulloblastoma and will be useful for probing therapeutic potential.»

Our strategy is to identify basic mechanisms of proteins involved in metabolism and DNA repair to gain better understanding in disease and also develop small molecule inhibitors to selectively targeting these proteins as potential therapeutics.

«Dark chocolate, a high source of polyphenols, and flavanols in particular, has lately received attention for its possible role in modulating obesity because of its potential effect on fat and carbohydrate metabolism, as well as on satiety... The research undertaken to date has shown promising results, with the possible implication of cocoa / dark chocolate in the modulation of obesity and body weight through several mechanisms including decreasing the expression of genes involved in fatty acid synthesis, reducing the digestion and absorption of fats and carbohydrates and increasing satiety.»

But because, unlike self - publishing, vanity publishing is a scam — a con — the hype and promo of a vanity company attempts to convince its potential consumer market (desperate aspiring writers) that there - is - a publishing and distribution mechanism, by completely obscuring the difference between being printed (which anyone with access to a Kinko's can achieve) and being - published -, whch is a complex business process involving widespread distribution.

We show the temperature changes that result from exchanging CO2 for CH4 using a variety of commonly suggested metrics to illustrate the trade - offs involved in potential carbon trading mechanisms that place a high value on CH4 emissions.

This will include researchers involved in developing prediction systems, understanding mechanisms of decadal and forced climate variability, and assessing the needs of potential users.

Do I have a mechanism for finding any name or variation thereof of a party involved in a potential matter in the history of the firm's work?

Although there are some cases that need to go directly to law enforcement, the point of the guide is to encourage individuals to report potential concerns internally so that companies have an early opportunity to address risk or potential misconduct, before the need to involve law enforcement; that employees of an organization have a safe and trustworthy mechanism to report information internally without any chance of reprisal.

Specifically, Ms. functioning should Lowell's current dissertation project aims have the capacity to to examine early childhood adversity and other mechanisms of action in the understand their own prediction of child maltreatment potential emotions, regulate those in substance - involved mothers.