«Thanks to a deeper understanding of cancer biology, we have
a potential new targeted therapy for multiple myeloma, and can better tailor treatment for kids with Wilms tumor.
Not exact matches
«The most exciting result is the discovery of PGC1 - alpha as
potential new target of
therapy for early intervention Scherzer,» says.
Researchers are also exploring a
potential new therapy that could
target H3K27me3 and reverse the lowered levels.
A
new wave of
potential immune
therapies aims to
target the network of complex sugars that coat cancer cells, Esther Landhuis reported in «Cancer's sweet cloak» (SN: 4/1/17, p. 24).
Despite this
new direction for identifying
targets for pharmaceutical interventions against RP, the researchers underscore that gene
therapy still has great
potential and possible benefits, and they are actively pursuing efforts with this approach for several forms of RP.
By tracking and understanding which host cell pathways are manipulated by these T. gondii proteins, scientists can identify
potential new targets to develop more effective
therapies against highly aggressive solid tumors.
Genes that increase risk for AD are
potential targets for
new disease - modifying AD drug
therapies.
Dr. Martinez - Agosto noted, «Looking at the functionality of these genes and their effect on the immune response has great
potential for accelerating the development of
new targeted therapies.»
Professor Moffatt said: «The genes we identified represent
new potential drug
targets for allergic diseases as well as biomarkers that may predict which patients will respond to existing expensive
therapies.»
So they are a
potential target for
new therapies for the disease which is incurable according to the present state of research.
This
new knowledge is also making precision medicine a reality by enabling the development of highly
targeted therapies that offer the
potential for improved treatment outcomes, especially for patients battling cancer.
Further investigation into the enzyme could create
potential targets for
new therapies for metabolic conditions, said William Lowe, M.D., a senior author of the study and professor of medicine at Northwestern University Feinberg School of Medicine.
Her work - published in December 2007 - revealed genes involved in drug resistance and in evading the immune system, giving researchers
potential targets for
new therapies and vaccines.
«It suggests to us that
targeting the pathways used in regulating cell fate decisions — how stem cells choose between cell proliferation and differentiation — could be a more effective way of halting tumours in their tracks and lead to
potential new therapies.»
Dr. Feener's work is critical in elucidating one such
potential target for a
new DME
therapy,» said Helen Nickerson, Ph.D., Director of Translation Research at JDRF, which helped support Dr. Feener's research.
University of California San Francisco researchers may have discovered why the experimental anti-cancer drug Onyx - 015 works more broadly than had been expected, a finding that could solidify and expand use of the drug and which reveals a
potential new target for
therapy that could prompt the development of other cancer drugs.
As MD Anderson moves toward molecular characterization of the cancers of all our patients, allowing their optimal assignments to promising
new targeted therapies and
potential identification of biomarkers of response and resistance, the department's mission includes thematic translational research and preclinical molecular pathology research.
Additional insight into the biology of ER - positive breast cancers, particularly the higher risk luminal B cancers, could aid in identifying
potential targets and
new, effective
therapies.
They provide a
new target for
potential therapies, and they furnish a model system for more rapid and less expensive study of prion diseases and
potential treatments.
These studies support the idea that nutrient transporters can be exploited as
potential drug
targets for cancer
therapy and usher us into a
new era of novel cancer therapeutics beyond kinase inhibitors and growth factor receptor blockers.
By identifying novel molecular
targets and
potential new drugs, this powerful technological structure will contribute significantly to groundbreaking research towards the development of
new anti-cancer
therapies.
Although recently approved
therapies can increase progression - free survival by a few months, «we think this novel screening system has the
potential to uncover
new, more effective medications that could be
targeted more specifically at a patient's cancer,» Lengyel said.
Both research teams are trying to discover
potential new drug
targets that not only reduce skin discomfort and itch, but also are safer and associated with fewer side effects than currently available
therapies.