In a bid to harness
the potential of embryonic stem cells, surgeons in California have implanted lab - grown retinal cells into the eyes of two patients going blind from macular degeneration.
All
the potential of embryonic stem cells might be harnessed with the new techniques — without the political and moral controversy associated with destroying a fertilized egg.
«That started a lot of excitement that there might be these adult stem cells that had
the potential of embryonic stem cells,» says stem cell researcher Amy Wagers of the Joslin Diabetes Center in Boston.
«Then there were fat stem cells,» Daley continued, reciting a litany of alternative ways to tap into the therapeutic
potential of embryonic stem cells.
Scientists recently announced that they have found a way to turn human skin into cells that have all the therapeutic
potential of embryonic stem cells.
Starting in 2007, in the same French Institute of Health and Medical Research (INSERM) lab where he did his Ph.D., Catelain worked to harness
the potential of embryonic stem cells for treating cardiac diseases.
Not exact matches
Proponents
of the anything - goes position assert that the
potential scientific and medical benefits
of embryonic stem -
cell research override all other considerations» and therefore restrictions on the funding and scope
of this research are unwarranted.
Proponents
of the anything - goes position assert that the
potential scientific and medical benefits
of embryonic stem -
cell research override all other considerations» and....
Embryonic stem cell research has the
potential to save millions
of lives, but this is being prevented by religious radicals and therefore religion is detrimental to the preservation
of life.
«We've shown that SIF - seq can be used to identify enhancers active in cardiomyocytes, neural progenitor
cells, and
embryonic stem cells, and we think that it has the
potential to be expanded for use in a much wider variety
of cell types,» Dickel says.
«Perhaps there are some mammary gland
stem cells that can be coaxed to have a slightly broader
potential than normal, but I very much doubt that
embryonic - like
cells normally exist in the breast,» says Robin Lovell - Badge
of the National Institute for Medical Research in London.
Research involving the derivation and use
of embryonic stem (ES)
cells is permissible only where there is strong scientific merit in, and
potential medical benefit from, such research.
«It's an exciting development, and we await the outcome over the next year to see how well these
cells integrate, and if there are any
potential adverse reactions,» says Mike Cheetham
of the Institute
of Ophthalmology at University College London, one site where research is under way into a human
embryonic stem -
cell treatment for AMD.
Since
embryonic stem cells can differentiate into any type
of tissue, they have the
potential to treat an almost unending array
of medical conditions — replacing damaged or lost body parts or tissues, slowing degenerative diseases, even growing new organs.
The results help fill in the scientific puzzle kicked off by Dolly's cloning, which proved that mammalian egg
cells were capable
of dissolving the genetic roadblocks that limit the
potential of most adult
cells to give rise to only a single type
of tissue — that
of the organ from which they hail — whereas
embryonic stem cells have the
potential to become virtually any kind
of body tissue.
Stem cell researchers maintain that whatever the potential of adult stem cells, embryonic research could help them achieve
Stem cell researchers maintain that whatever the
potential of adult
stem cells, embryonic research could help them achieve
stem cells,
embryonic research could help them achieve it.
A fix for broken rat hearts Scientists this week successfully implanted human
embryonic stem cells into rats that suffered heart attacks, coming a heartbeat closer to realizing the full
potential of such therapy.
In their experiments, about 20 percent
of embryonic stem cells lacking the microRNA exhibited expanded fate
potential.
There is promising news today for those who hope to turn the
potential of undifferentiated
stem cells into medical miracles: Researchers are reporting a way to produce insulin - producing
cells from mouse
embryonic stem cells.
To tap
embryonic stem cells» therapeutic
potential, researchers must learn how to coax them to become a specific type
of cell that can then be transplanted into the body.
Vowing to veto the legislation, Bush said before the vote that the «reports give us added hope that we may one day enjoy the
potential benefits
of embryonic stem cells without destroying human life.»
Other
potential uses
of embryonic stem cells include investigation
of early human development, study
of genetic disease and as in vitro systems for toxicology testing.
Research led by the Babraham Institute with collaborators in the UK, Canada and Japan has revealed a new understanding
of how an open genome structure supports the long - term and unrestricted developmental
potential in
embryonic stem cells.
Adult and
embryonic stem cells are complementary subjects
of research and studying them side by side offers the greatest
potential to rapidly generate new therapies.
The
potential of iPS
cells to help treat everything from damaged heart tissue to Parkinson's disease, has prompted intensive research that has looked into the use
of skin fibroblast
cells as an alternative to controversial
embryonic stem cells.
After hearing a brief explanation that laid out the different sources
of stem cells (but left undiscussed their current uses or future
potential for therapy), the respondents offered a slightly more nuanced set
of views, and only a slight majority (52 %) supported
embryonic stem cell research.
While the
potential of adult
stem cells has been understood for some time, researchers have argued that the pluripotency
of embryonic stem cells — their ability to be transformed into most if not all
of the various
cell types
of the body — make them more valuable both for research and potentially someday for treatment.
The social, economic and personal costs
of the diseases that
embryonic stem cells have the
potential to treat are greater than the costs associated with the destruction
of embryos.
\ n3) There are «pluripotent»
stem cells which are created from skin
cells and offer the
potential for becoming different
cells similar to the hypothetical benefits
of embryonic stem cells, but they do NOT involve any moral controversy.
Embryonic and fetal
stem cells have the
potential to morph into a greater variety
of cells than adult
stem cells do.
My post-doctoral work on the identification
of genes required for normal germ line development and fertility led to the discovery that the germ line is exquisitely sensitive to mutations in components
of the mitotic spindle that have the
potential to lead to aneuploidy — this sensitivity may also extend to
embryonic and adult
stem cells.
Leading US research institutions may stop studying several federally - fundable linkurl:
embryonic stem cell; https://www.the-scientist.com/blog/display/54749/ lines due to
potential ethical problems surrounding the creation
of the lines.
«Finally, to assess the
potential fate
of mtDNA under condition when the
cells can replicate extensively (longer than allowed by UK law), they derived human
embryonic stem cell (hESC) lines from five ePNT blastocysts.
Critical issues include: (i) heterogeneity in
stem cell populations (ii) regulation of cell fate choices; (iii) declining tissue performance with age and exposure to environmental injuries; (iv) the use of iPS and Embryonic Stem (ES) cells, and reprogramming methods for phenotyping disease states and potential use of these stem cells in the cli
stem cell populations (ii) regulation
of cell fate choices; (iii) declining tissue performance with age and exposure to environmental injuries; (iv) the use
of iPS and
Embryonic Stem (ES) cells, and reprogramming methods for phenotyping disease states and potential use of these stem cells in the cli
Stem (ES)
cells, and reprogramming methods for phenotyping disease states and
potential use
of these
stem cells in the cli
stem cells in the clinic.
The guidelines were originally produced to offer a common set
of ethical standards for the responsible conduct
of research using human
embryonic stem cells, which have the
potential to produce all the body's
cell types.
Unlike
embryonic stem cells, which are developmental blank slates that can generate virtually all types
of cells found in adult humans, adult
stem cells are thought to possess limited
potential to transform into
cells found in their tissues
of origin.
Shaheen, whose granddaughter was recently diagnosed with Type 1 diabetes, and Fox have joined a majority
of medical researchers around the country who believe that
embryonic stem cell research offers more
potential than other
stem cell lines, which have also attracted research attention.
Virtually identical to human
embryonic stem cells (hESCs) except for their origin
of isolation, the recently created induced pluripotent
stem cells (iPSCs)(Yu et al., 2007; Takahashi et al., 2007) hold much
potential for use in regenerative therapies.
«This discovery will advance our understanding
of stem cell epigenetics and chromatin structures, provide
potential mechanisms on maintaining the hallmark properties
of ES
cells, and help researchers with the rich source
of information to better understand some
of the unique features — such as self - renewal and pluripotency —
of human
embryonic stem cells,» said Ng Huck Hui, Ph.D., senior group leader at GIS and a member
of the Singapore team that conducted this research.
Despite the promise
of iPS
cells, scientists are still struggling to understand whether their developmental
potential is equivalent to that
of embryonic stem cells.
The challenge takes on even more urgency with recent developments, including a federal administration now more open to exploring the
potential of stem cells, the recent FDA approval
of a human trial involving
embryonic stem cells, as well as the reported case
of a young boy who developed a brain tumor four years after receiving a
stem -
cell treatment for a rare genetic disorder.
Alternatively,
embryonic stem (ES)
cells have emerged as a
potential source
of less immunogenic hematopoietic progenitor
cells (HPCs).
Using cloning technology to derive
embryonic stem cells genetically identical to a patient is potentially very important, not only to provide a source
of cells that may be used to cure patients, but also to allow for genetic disease to be studied and
potential drug treatments to be explored in the laboratory.
The authors highlight the successful application
of both induced pluripotent
stem cells and
embryonic stem cells for this first example
of the in vitro formation
of functional and mature skeletal muscle tissue, thereby also establishing the
potential for patient - specificity in disease modeling, drug development, and possible muscle repair.
Here we report that cultures
of expanded
potential stem cells can be established from individual eight -
cell blastomeres, and by direct conversion
of mouse
embryonic stem cells and induced pluripotent
stem cells.
His pioneering mouse
embryonic stem (ES)
cell work in the 1980s, demonstrating germ - line transmission and the great
potential of ES
cells to generate mice carrying mutations in endogenous genes, established milestones in a field that saw the award
of the 2007 Nobel Prize in Physiology or Medicine to Mario Capecchi, Martin Evans, and Oliver Smithies.
Embryonic stem (ES)
cells have high self - renewal capacity and the
potential to differentiate into a large variety
of cell types.
«President Obama's executive order today lifting federal restrictions on
embryonic stem cell research is years overdue and will now allow the full
potential of scientific research and discovery to be realized.
However welcome the recent announcement that a team
of scientists based at Newcastle University, has grown a section
of human liver using
stem cells from umbilical cords, rather than from the more controversial source
of embryonic stem cells, and whatever the eventual promise or
potential of harvesting organs for transplantation from genetically modified pigs, the benefits
of either
of these two pioneering techniques to currently dying / suffering patients, remain both elusive and distant.