Working with animal models, researchers at Joslin Diabetes Center now have demonstrated
the potential of giving a drug in combination with tPA that might improve stroke outcomes and increase the window of opportunity for the therapy.
Not exact matches
The
potential deal sent both stocks soaring as it would tie up two giants from Quebec and
give Metro an expanded foothold in the
drug business, mirroring Loblaw Cos.» purchase of Shoppers Drug Mart four years
drug business, mirroring Loblaw Cos.» purchase
of Shoppers
Drug Mart four years
Drug Mart four years ago.
Its positions in Southern California, the Chicago region, the Northeast, as well as Florida place it within large population centers, which, according to the DEA,
gives it access to «
potential high density
drug markets that TCOs will look to exploit through the street - level
drug distribution activities
of urban organized crime groups / street gangs.»
«I think the Shoppers
Drug Mart deal certainly has the
potential to be a real home run for them and
give them the opportunity to shift their strategies to address some
of the changes that are taking place in the marketplace,» said Nixon.
Furthermore, Celgene is generating free cash flow at a rate
of over $ 1 billion per quarter,
giving it plenty
of options to acquire new
drugs, such as with the deal it announced earlier this month to buy Impact Biomedicines and its
potential blockbuster
drug for a rare form
of blood cancer, and its latest announced buyout
of CAR - T developer Juno Therapeutics.
The narrow point is: If notable cost - cutter Valeant gets its hands on Allergan, it will short - sightedly cut off development
of DARPin (it's a
drug or something 1) to save $ 350 or $ 400 million,
giving up $ 20 billion
of potential revenue.
While it was once true that most testing
of potential new
drugs took place in medical schools and teaching hospitals, that is no longer the case, and in Elliott's view the change has
given rise to serious problems and abuses.
Given that some Chinese poultry farmers allegedly used large quantities of illegal drugs in raising chickens sold to KFC, and given the potential vulnerability of young school children eating such chicken, a lifting of the export ban on raw Chinese poultry is a cause for serious con
Given that some Chinese poultry farmers allegedly used large quantities
of illegal
drugs in raising chickens sold to KFC, and
given the potential vulnerability of young school children eating such chicken, a lifting of the export ban on raw Chinese poultry is a cause for serious con
given the
potential vulnerability
of young school children eating such chicken, a lifting
of the export ban on raw Chinese poultry is a cause for serious concern.
The inclusion
of social supply in the bill also has the
potential to result in discriminatory impact on members
of black and minority ethnic groups,
given what is known about the over-representation
of members
of these groups at each stage
of the criminal justice response to
drug offences.»
«
Given the cost and
potential side effects associated with pregabalin, it is critical that we understand the efficacy
of this
drug,» Markman said.
«It's got more
potential in that you can
give drugs to people more easily than you can get light into their brains,» says Dimitri Kullmann
of University College London.
An editorial in the same issue
of the journal notes that
drug - based treatments for liver cancer are limited and that the UT Southwestern study showed «truly remarkable results that should prompt further research under preclinical settings,
given its
potential to lead to a paradigm shift in treatment.»
The good news about the complex interconnectivity is that the scientists also were able to find a
potential future point
of intervention: When they
gave a
drug that increased AMPA receptor expression on the cell surface, the spines assumed a more healthy, mature state.
«This is the first time that this specific protein - protein signaling complex has been identified in GBM, and it
gives us a new
potential target for
drug development,» says Fisher, Thelma Newmeyer Corman Endowed Chair in Cancer Research and co-leader
of the Cancer Molecular Genetics research program at VCU Massey, professor and chair
of the Department
of Human and Molecular Genetics at the VCU School
of Medicine, and director
of the VIMM.
«
Given the
potential for future lethal pandemics, effective
drugs are needed for the treatment
of severe influenza, such as that caused by H5N1 viruses,» says senior study author Yumiko Imai
of Akita University.
A CAREER in clinical research may conjure up images
of potential blockbuster
drugs being
given to volunteers in a state -
of - the - art hospital.
«
Given the therapeutic
potential of the nSMase target, we're now working closely with Drs. Barbara Slusher, Camilo Rojas, Ajit Thomas and colleagues at the Johns Hopkins
Drug Discovery facility to identify potent inhibitors
of the nSMase enzyme which can be developed for clinical use,» says Haughey.
Given the wide range
of prescription and over-the-counter
drugs on the market, and the number
of drugs that interact with supplements, alcohol and certain foods, Malani says it's hard for even medical professionals to catch all
potential interactions.
Because high doses
of opioids have the
potential to cause respiratory arrest or other dangerous side effects, doctors may hesitate to
give patients as much
of the
drugs as they need to relieve their pain, says David Soergel, chief medical officer at Trevena.
«
Given the broad
potential of this revolutionary
drug technology, it was critical to us to work closely with a leading academic medical institution.
An open - source content management system then would search through upwards
of a billion
drug combinations to find those with the greatest
potential to inhibit a
given tumor, or a billion hypothetical compounds to identify candidates for new
drug development.
With this knowledge, computer models can measure millions
of potential drug molecules against the tau protein,
giving immediate clues to suggest which should be tested further.
Potential limits to external generalizability include the intensive research assessments (up to 12 hours), the recruitment and treatment of patients in non — primary care academic settings, exclusion of participants with substantial concurrent psychiatric illness and drug abuse, and the limited time of treatment (16 weeks) given the chronicity and relapse potential in alcohol - dependent ind
Potential limits to external generalizability include the intensive research assessments (up to 12 hours), the recruitment and treatment
of patients in non — primary care academic settings, exclusion
of participants with substantial concurrent psychiatric illness and
drug abuse, and the limited time
of treatment (16 weeks)
given the chronicity and relapse
potential in alcohol - dependent ind
potential in alcohol - dependent individuals.
Being able to measure the navigational impairment caused by Alzheimer's disease in both species
gives us the
potential to directly compare results across species, including studies
of drug efficacy.
Did you know that half
of all psoriasis and psoriatic arthritis patients are currently dissatisfied with their conventional medical treatments?Is it any wonder, most are just
given a prescription for a pharmaceutical
drug and little to no attention is
given to any
potential triggers
of their psoriasis.
[25] The defendants argue that the reliability
of the plaintiff's evidence,
given the
potential memory loss from
drug use, is at issue in this case.
In addition,
given the high risk for
potential danger involved in many manufacturing workplaces, continuous scheduling
of drug screening for manufacturing companies is also both recommended, and often required.
A consistent message
given to young people is that there is NO safe level
of drug use and that any
drug has the
potential to cause harm.