Sentences with phrase «potential outcome of the trial»

[We] are naturally gearing up to deal with any potential outcome of the trial.»

Not exact matches

Consequently, they hope that their results will «motivate the incorporation of assays measuring ex-vivo T - cell function into ongoing and planned clinical trials of HDAC inhibitors, and that immunosuppression will be considered as a potential factor limiting the effectiveness of any observed outcomes.»

«Since several BACE1 inhibitors are currently being evaluated in clinical phase 3 trials for the treatment of Alzheimer's disease, the identification of potential side effects will be of great importance to ensure a positive clinical outcome,» said Dr. Jochen Herms, a Professor of translational brain research at Ludwig - Maximilians - University Munich.

Clinical trials found that it is safe to regularly infuse brain and lung cancer patients with 800 — 1000 times the daily recommended amount of vitamin C as a potential strategy to improve outcomes of standard cancer treatments.

Potential cardioprotection was based on generally supportive data on lipid levels in intermediate outcome clinical trials, trials in nonhuman primates, and a large body of observational studies suggesting a 40 % to 50 % reduction in risk among users of either estrogen alone or, less frequently, combined estrogen and progestin.2 - 5 Hip fracture was designated as a secondary outcome, supported by observational data as well as clinical trials showing benefit for bone mineral density.6, 7 Invasive breast cancer was designated as a primary adverse outcome based on observational data.3, 8 Additional clinical outcomes chosen as secondary outcomes that may plausibly be affected by hormone therapy include other cardiovascular diseases; endometrial, colorectal, and other cancers; and other fractures.3, 6,9

While this single study certainly doesn't constitute a proven scientific outcome, the results of a randomized controlled trial conducted in Boston certainly supports the real - world potential for co-treating our mind, along with our body to achieve better fertility outcomes.

The potential outcome of a retrial is hard to predict (as was the outcome of the original trial) and, in my opinion might result in a lower judgement for GYRO but not NO additional compensation..

Our board of directors recognized that there was a potential for creating significant value for shareholders by continuing operations, but on balance our board of directors concluded that the risks of a negative outcome, either due to failure of our research and development efforts to yield a successful outcome, or the failure to obtain necessary financing even with positive clinical trial data, and the resulting lower liquidation value in the future, outweighed the potential value to shareholders from continuing operations.

Initial projects have focused on predicting fraudulent activity in relation to claims, the likelihood of disputes going to trial or to settlement, and potential litigation outcomes».

In addition, your criminal defense attorney can advise you about the pros and cons of accepting a plea deal, the potential consequences of going to trial, and negotiate with the prosecution on your behalf to fight for the best possible outcome in your case.

So far, projects at the lab have explored predicting fraud in relation to claims, the likelihood of disputes going to trial or settlement, as well as potential litigation outcomes.

This process of information sharing and synthesis provides the parties with an opportunity to formulate a more complete view of the conflict and gain enhanced insight into the relative strengths and weaknesses of their case, weigh the chances of success at trial and explore the potential ingredients needed to fashion a fair and reasonable negotiated outcome.

From a range of disciplines the review determined that, to be successful, programmes must involve a partnership between the family and nurse, focus on goals that parents prioritise, build competencies, be non-stigmatising and maintain continuity of care.48 The third review went on to investigate specific evidence - based interventions that focused on this trial's primary outcome areas and had the potential to enhance the effectiveness of SNHV programmes.

We implemented unadjusted and adjusted analyses (potential prognostic factors listed in table 2) of the outcomes (all quantitative) by using random effects linear regression models fitted by maximum likelihood estimation to allow for the correlation between the responses of participants from the same maternal and child health centre.29 We present means and standard deviations for each trial arm, along with the mean difference between arms, 95 % confidence intervals, and P values.

If there is insufficient information to control for clustering, we will enter outcome data into RevMan using individuals as the units of analysis, and then conduct a sensitivity analysis excluding such studies (Sensitivity analysis), to assess the potential biasing effects of inadequately controlled clustered trials (Donner 2001).

However, the potential of universal prevention in early childhood to improve mental health remains largely unexplored.2 5 7 We previously published short - term outcomes at toddler age11 of the first cluster randomised trial of a truly universal early parenting programme, Toddlers Without Tears, designed to be offered to all parents in the community and aiming to prevent externalising behaviours using anticipatory guidance before any developmental onset.