Sentences with phrase «potential target»
Together, they discovered that this response pointed to a protein on the surface of the parasite, called CSP, a potential target for protective antibodies.
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The potential target was probably Iran.»
What is particularly exciting about this research is that it opens up a whole new chemical system, called the endocannabinoid system, as a potential target for new avenues of research which could include illnesses like dementia.
This work led to the identification of dual leucine zipper kinase (DLK) as a key mediator of RGC cell death, and an exciting potential target for glaucoma neuroprotection.
The results contribute to our basic understanding of mitochondria and suggest that EXD2 could be important for fertility and represent a potential target for cancer therapy.
New study have identified the inhibitor of a protein involved in cell protection as a potential target for novel Alzheimer's treatment
Their findings on telomeres, the stretches of DNA at the ends of chromosomes that protect our genetic code and make it possible for cells to divide, suggest a potential target for preventive measures against cancer, aging and other diseases.
Apr. 5, 2018 — Lung diseases of infancy and aging share a molecular signature, pointing to a potential target for treatment and prevention.
Human myeloperoxidase: a potential target for molecular MR imaging in atherosclerosis.
We know that regeneration is an orchestra of communication signals from a number of different tissues, and those tissues have to turn on genetic light switches at the same time, so part of the challenge in defining those circuits in greater detail is going to be interrogating these miRNAs and their potential target genes in a mammalian system.
Dr. Feener's work is critical in elucidating one such potential target for a new DME therapy,» said Helen Nickerson, Ph.D., Director of Translation Research at JDRF, which helped support Dr. Feener's research.
Diagram of the path of New Horizons towards its next target, a Kupier Belt object called 2014 MU69 (nicknamed «PT1» for «Potential Target 1»).
Down - regulation of the antisense mitochondrial non-coding RNAs (ncRNAs) is a unique vulnerability of cancer cells and a potential target for cancer therapy.
«We now have a potential target to improve the selective function of the endometrium.»
Dr. Kirino says that «further studies to understand how SHOT - RNAs promote cell proliferation may lead to the use of SHOT - RNAs as potential target candidates for future therapeutic applications in breast and prostate cancers.»
Selectively expressed on GBM and absent on surrounding brain tissue, the interleukin - 13 receptor α chain variant 2 (IL13Rα2) was identified as a potential target for therapy for GBM two decades ago.
To understand the functional role of miR - 7 in CSCs, we first searched its potential target genes that may be involved in stem cell physiology using multiple database including TargetScan, PicTar, miRanda, and SLOAN - Kettering.
Linking observed memory deficits to the PDE4A5 enzyme «suggests a potential target for alleviating the effects of sleep deprivation in humans,» says neuroscientist Sam Deadwyler of Wake Forest University in Winston - Salem, North Carolina.
Together, these new findings highlight NS1 as an instigator of dengue - associated vascular leak and thus pinpoint a potential target for dengue drugs and component for dengue vaccines.
«Everything in that pathway becomes a potential target.»
Studies from a group at the University of Glasgow, which are published in the same issue of the journal, show the importance of calcineurin through different stages of the malaria life - cycle, implicating the protein as a potential target for blocking malaria transmission.
These findings add an important and previously overlooked component to the causes of dengue vascular leak, identify a new potential target for dengue therapeutics, and support inclusion of NS1 in dengue vaccines.
Many phenomena, such as certain protein folds or a drug binding to a potential target, happen over the course of a few seconds, minutes or even days.
«There was a concern that the space shuttle launch would be a potential target, especially so close after the attacks,» Beutel explained.
Prior research has found that almost all head and neck cancer cells display an over-abundance of the protein, and it had been suggested in the literature as a potential target.
And we have a potential target to be able to influence that activity to change the properties of cancer cells,» says Professor Richards.
The length of the telomere «caps» of DNA that protect the tips of chromosomes may predict cancer risk and be a potential target for future therapeutics, University of Pittsburgh Cancer Institute (UPCI) scientists will report today at the AACR Annual Meeting in Washington, D.C.
This provides a potential target for treating triple negative breast cancer, the most aggressive form of the disease.
So they are a potential target for new therapies for the disease which is incurable according to the present state of research.
Now we know the motor they use to invade, he says, so we have a potential target to think about disrupting.
Sodium channels are implicated in many serious conditions such as heart disease, epilepsy and pain, making them an important potential target for drug therapies.
«This work validates a new potential target for the treatment of diabetes,» Liu said.
That's because other APOBEC enzymes cause cancer - related mutations — a kind of «friendly fire» that makes these enzymes a potential target for new drugs.
Now, we can use copper - catalyzed conditions which are applicable to versatile fluoroalkenes to replace fluorine atoms with boron, which opens up a huge range of potential target molecules and should boost the use of fluoroalkenes in pharmacological studies.»
The protein, called neuregulin - 1, has many forms and functions across the brain and is already a potential target for brain disorders such as Parkinson's disease, amyotrophic lateral sclerosis and schizophrenia.
«Identifying HIC1 provides a potential target to modulate intestinal inflammation,» said Prof Zaph, who led these studies.
Identified eight highly potential target genes for binding by miR -124-3p, genes whose function is also reported to be critical in brain physiology during stress and MDD pathogenesis.
In post-mortem brains of 15 controls and 15 MDD subjects, the MDD group showed significant increase in the expression of miR -124-3p, and expression of three of the potential target genes was significantly lower.
Four of these potential target genes were significantly down - regulated in the prefrontal cortex of corticosterone - treated rats, and this down - regulation inversely correlated with miR -124-3p levels.
Significant binding by miR -124-3p to two of the potential target genes was seen, as measured from immunoprecipitated RNA - induced silencing complexes.
One such regulatory element, the riboswitch, has excited interest as a potential target for antibiotics.
These findings open the door for future research considering the prion protein as a potential target in the development of treatments for major depression and related disorders.
«Therefore, it is important to consider this receptor subtype as potential target for the treatment of psychiatric illnesses characterized by alterations in personal relevance attribution.»
«Our results show that associations between eating behaviours and cardiovascular risk appear early in life and may be a potential target for early intervention,» writes Dr. Navindra Persaud, family physician and researcher at St. Michael's Hospital, Toronto, Ontario.
«This is the first time that this specific protein - protein signaling complex has been identified in GBM, and it gives us a new potential target for drug development,» says Fisher, Thelma Newmeyer Corman Endowed Chair in Cancer Research and co-leader of the Cancer Molecular Genetics research program at VCU Massey, professor and chair of the Department of Human and Molecular Genetics at the VCU School of Medicine, and director of the VIMM.
HIV has often been linked to impairment of lipid metabolism, making ACSS2 a promising potential target for an HIV cure.
«Potential target for treating mitochondrial disorders.»
The research was published in the scientific journal Nature Genetics this week and scientists hope it will provide another potential target for therapy development.
Expanding the number of potential target stars obviously raises the SETI odds considerably.
«Potential target for revolutionary antibiotics.»