Sentences with phrase «potential therapeutic applications»

The I - Stem laboratory is an institution dedicated to the exploration of potential therapeutic applications of human ES and iPS cells and therefore, is rather a scientific center focusing on «Research and Development».

In 2001, Chris Orvig was happy when his team had synthesized a molecule with potential therapeutic applications.

SOX2 is one of two key genes researchers use to generate induced pluripotent stem cells (iPSCs), which are capable of differentiating into all cell types for research and potential therapeutic applications.

This is just one of the many potential therapeutic applications of iPS cells.

The science of genetics is built on Gregor Mendel's work on peas; Barbara McClintock discovered transposable elements — «jumping genes» — while working on maize; the science of «RNA interference» and its potential therapeutic applications derives from early studies of cosuppression in transgenic purple petunias.

«I am most excited about the future potential therapeutic applications of this discovery against cancer.

The study paves the way for CRISPR - Cas9 as a powerful gene editing tool with potential therapeutic applications for inherited diseases — leading to more widely available gene therapy techniques.

«The structure led us to propose a mechanism for the receptor selectivity of the HIV virus» with potential therapeutic applications, she says.

While the researchers can not yet point to a potential therapeutic application of their findings, identifying genetic changes that underlie MND is the first step in finding ways to manipulate these changes using gene therapy.

The present review describes the cellular signalling pathways regulating mammalian autophagy and highlights the potential therapeutic application of autophagy inducers in neurodegenerative disorders.

Several small molecules modulating autophagy have been identified that have potential therapeutic application in diverse human diseases, including neurodegeneration.

Not exact matches

Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.

Cannabis is in Schedule One, for substances that have no therapeutic application and a high potential for abuse.

In addition to uncovering compounds with therapeutic potential for Alzheimer's disease, this research presents a new approach for identifying proteins that bind to amyloid fibrils — an approach that could have broad applications for treating many diseases.

«While inclusion of such MIPs in a cosmetic product will require much formulation development, it is clear to see the potential of imprinting technology in a range of topical applications, both cosmetic and therapeutic.»

The research has potential applications in therapeutic work — for example, Dikker's team would like to test game - like neurofeedback in high - functioning autistic teens, to see if the method can help them respond better to social cues.

The role of Apelin and Elabela in establishing the circulatory system makes them potential targets in future development of therapeutic applications for illnesses ranging from the various cancers, and cardiovascular diseases, to even metabolic diseases such as diabetes.

One of the potential applications of this system is to measure the quantity of therapeutic antibodies in the blood and decide whether it is necessary to administer any extra medication.

But, these squishy packages are hard targets for potential therapeutic and diagnostic applications that exploit nanomaterials, from quantum dots that light up specific tissues to nanocages carrying drug payloads.

Dr. Kirino says that «further studies to understand how SHOT - RNAs promote cell proliferation may lead to the use of SHOT - RNAs as potential target candidates for future therapeutic applications in breast and prostate cancers.»

PrediXcan has the potential to identify gene targets for therapeutic applications faster and with greater accuracy than traditional methods.

The specific vocation of I - Stem is to explore all the therapeutic potential of human pluripotent stem cells for applications in patients affected by rare diseases of genetic origin.

Also, pESC lines, that carry isogenic genome information from the oocyte donors, can be derived and may represent a potential alternative source of stem cells for basic scientific studies as well as novel therapeutic application.

«The inflammation resolving targeted nanoparticles have shown exciting potential not only for the potential treatment of atherosclerosis as described here, but also other therapeutic areas including wound repair, for example, as described in the Feb. 9 online issue of Journal of Clinical Investigation, in addition to other applications currently underway with our collaborators,» Farokhzad said.

Our next step was to study in detail the potential of rainbow PNBs for diagnostic and therapeutic applications for the same cell model of prostate cancer cells growing amongst normal stromal cells.

Understanding the Biological Functions of Antimicrobial Peptides and Their Potential in Therapeutic Applications

Coordinate the full drug discovery process to identify potential therapeutic and medical applications

Two grant applications have been submitted since the completion of this study, to further investigate the role of therapeutic alliance & other factors in the treatment of depression among drug & alcohol users within AOD services and to investigate the needs of benzodiazepine users in treatment, including potential mental health needs.