These discoveries not only enhance our fundamental understanding of these conditions, but also point to
potential therapeutic strategies for treating them.
In the study published in the journal Science Signaling, the team led by LLuís Espinosa, investigator of IMIM's research group into stem cells and cancer, have shown that inhibition of endosomal activity is
a potential therapeutic strategy for the treatment of cancers with the BRAF mutated gene.
The findings «demonstrate the salutary effects of blocking CSE during apnea and point to
a potential therapeutic strategy for human sleep apnea,» according to the authors.
Furthermore, inhibition of SA1 sensitized the SA2 - deficient cancer cells to PARP inhibitors in vitro and in vivo, providing
a potential therapeutic strategy for patients with SA2 - deficient tumors.
Not exact matches
«We have identified a pathway in microglia that may be targeted to ultimately slow disease progression in ALS and are exploring
potential therapeutic strategies and may have broader implications
for diseases such as Alzheimer's and Parkinson's Disease amongst others.»
A new study in American Journal of Physiology — Heart and Circulatory Physiology identifies the involvement of a protective response pathway, the heme oxygenase system, that has
potential as a new
therapeutic strategy for cardiovascular diseases.
The technique has the
potential to benefit a large population of patients with neurodegenerative disorders, where there remains a specific unmet need
for blood - brain penetrating
therapeutic delivery
strategies.
«Researchers discover a
potential new
therapeutic strategy for pancreatic cancer: Researches have have isolated a subpopulation of cancer - associated fibroblasts, which promote tumour growth.
The nanoparticles developed by Dr. Rana and colleagues offer a
potential new
strategy for delivering this powerful
therapeutic approach.
«Overall, our studies show a new
therapeutic strategy for the treatment of chronic inflammatory pain that deserves further study
for its
potential use in clinical medicine,» says the professor of the University of Valencia.
But at his presentation at the fifth
Strategies for Engineered Negligible Senescence (SENS) biomedical conference, Teitell revealed that their focus had shifted: «our studies show an unanticipated role
for PNPASE in mediating the translocation of RNAs into mitochondria and provide a
potential therapeutic route
for halting or reversing the decline in mitochondrial function with aging [emphasis mine].»
We now have an excellent model
for this childhood disorder to learn about the molecular causes of disease and to test
for potential therapeutic strategies.
We have also set out to exploit the specificity of carbohydrate recognition and the ensuing membrane mechanical
potential resulting from clustering of glycosphingolipids
for the development of innovative
therapeutic delivery
strategies for the treatment of cancer and infectious disease.