Most iPS cells have been derived through the use of viral vectors and are not ideal for the study and
potential treatment of human diseases.
Not exact matches
However, Dr. Kissler's group discovered that reducing levels
of the RGS1 protein did not slow the progression
of the
disease in mouse models, suggesting that it may not offer much
potential for
human treatment.
Now, in a new study published in the journal Cell, scientists at the Salk Institute for Biological Studies have discovered that a synthetic form
of vitamin D, calcipotriol (a drug already approved by the FDA for the
treatment of psoriasis), deactivates the switch governing the fibrotic response in mouse liver cells, suggesting a
potential new therapy for fibrotic
diseases in
humans.
Salk researchers found that a drug already approved by the FDA for the
treatment of psoriasis deactivates the switch governing the fibrotic response in mouse liver cells, suggesting a
potential new therapy for fibrotic
diseases in
humans.
This blueprint should come in handy in sussing out the molecular basis
of human variation and
disease and in discovering
potential new
treatments.
The Clinical Research Forum Board
of Directors selected winners based on the degree
of innovation and novelty involved in the advancement
of science; contribution to the understanding
of human disease and / or physiology; and
potential impact upon the diagnosis, prevention and / or
treatment of disease.
Scientists believe that stem cell therapy has the
potential to dramatically change the
treatment of human disease.
«These findings have
potential implications for the prevention and
treatment of human heart
disease, once we better understand Irx3's role in the
human heart,» said Dr. Bruneau.
Today, nuclear cloning is one
of the essential tools in Dr. Jaenischs laboratory studies
of human diseases, including his groundbreaking work on the nature and
potential treatment of cancer.
After huge leaps forward in recent years, we're edging ever closer to
human trials
of huntingtin lowering or «gene silencing» as a
potential treatment for Huntington's
Disease.
Thus, the lab's approach may hold great promise for
potential treatment of (neuro) inflammation - related
human diseases both in and outside the central nervous system.
The work by the Houdusse team and Cytokinetics highlights how specific modulators
of myosin activity have great
potential to provide new
treatments against
human diseases.
The successful differentiation
of iPS cells into RPE represents a significant advance in the search for a
potential cell source for the
treatment of human neural retinal
diseases.
Stem cell research has the
potential to revolutionize the
treatment of many
human diseases.
Umrao Monani, Ph.D., assistant professor
of neurology, searches for
potential treatment strategies using genetically modified mice that mimic the
human disease.
An important step in developing effective
treatments for
human disease is finding an effective animal model
of the
disease to test
potential therapies.