«We are exploring alternative directions for developing this compound, including
potential use of the animal efficacy rule,» Cihlar said, referring to a regulatory mechanism under which the U.S. Food and Drug Administration may consider efficacy findings from adequate and well - controlled animal studies of a drug in cases where it is not feasible or ethical to conduct human trials.
Not exact matches
As part
of its pitch, the company explains to
potential customers that the so - called «net present value»
of a $ 7,000 saddle is actually less than the all - in cost
of using an ill - fitting one — expenses that include frequent vet bills, replacement saddles and even the costs associated with the premature death
of the
animal due to saddle - related health problems.
Following the release
of these findings, The HSUS filed complaints with the SEC and FTC, alleging that Seaboard makes grossly false and misleading statements about
animal welfare to shareholders,
potential investors and the public, including that the company
uses the «most humane practices.»
The college will continue to study pest and nutrient management, and identify new opportunities for the
use of hemp stalks as
animal bedding and the
potential for the plant to be
used for soil remediation.
After early
animal studies demonstrated that the synthetic cannabis extract dronabinol improved respiratory stability, recent studies in humans have explored the
potential use of dronabinol as an alternative treatment for sleep apnea.
Page and his colleagues, who
use animal models to understand how autism risk factors impact the developing brain and to identify
potential treatments for the condition, have found that
animals with mutations in the autism risk gene phosphatase and tensin homolog (Pten) mimic aspects
of autism, including increased brain size, social deficits and increased repetitive behavior.
Nadeau also studies the
potential impacts
of climate change on species around the globe,
using modeling, field observation and experiments to predict where species are most vulnerable and determine how conservation groups can best mitigate the negative impacts
of climate change on
animal populations.
The first
of these will focus on the
potential use of genome editing in human reproduction to avoid the transmission
of heritable genetic conditions, and the second on livestock to improve systems
of animal husbandry and food production.
«The big question about why we mammals affiliate with one
potential partner versus another finally has a handle we can
use in a small
animal model,» says Lucy Brown at the Albert Einstein College
of Medicine in New York.
Researchers at the University
of Minnesota have developed an
animal research model for facioscapulohumeral muscular dystrophy (FSHD) to be
used for muscle regeneration research as well as studies
of the effectiveness
of potential therapies for FSHD.
The corridor has been considered a
potential route for human and
animal migrations between the far north (Alaska and Yukon) and the rest
of North America, but when and how it was
used has long been uncertain.
«It has the
potential to inform clinical practice and also guides us about the relevance
of animal models
of human disease and how we can reduce and refine their
use.»
As well as boosting our understanding
of animal behaviour, the moment hints at the
potential for
using algorithms to analyse any activity where information is transmitted — including our daily activities (see «Scripts for life «-RRB-.
The
use of animal products is a significant clinical challenge due to
potential zoonotic infections, which can be spread between
animals and humans.
This has led to a demand for people who can understand data collection techniques and analyze vast amounts
of data, categorize the data sets, develop models to test hypotheses that can then be
used to develop drugs, and test
potential candidates in
animals.
For example, the flagship journal
of the Public Library
of Science, PLOS ONE, was the only journal that called attention to the paper's
potential ethical problems, such as its lack
of documentation about the treatment
of animals used to generate cells for the experiment.
The
use of robots to influence collective
animal behavior is also viewed as a
potential means to protect marine wildlife, including birds and fish, in the wake
of environmental hazard.
Using acoustics to monitor these organisms could also help scientists study how these
animals could be affected by climate change, and the consequences
of potential commercial fishing projects, she said.
Scientists have long known about the
potential environmental effects stemming from the
use and disposal
of products aimed at keeping people healthy and clean, but with roughly seven in 10 Americans owning at least one pet,
animal medications and other care products are slowly beginning to move into the spotlight too.
For reminder, the Directive allows the
use of animals in research where the
potential medial, veterinary and scientific benefits are compelling and there is no other viable alternative method.
It is also intended for post-docs and scientists already working in certain
of these fields and who are interested in expanding their knowledge on the
potential applications
of these new techniques to their models or in neighbouring pathophysiological models
of analysis
of genes or diseases
using genetically modified
animals.
The researchers are now testing the efficacy
of the technique in
animal models to verify its
potential for therapeutic
use.
Dr. Robert Urban
of Johnson & Johnson will address how Organ - Chips are being
used by the pharmaceutical industry today and the
potential the technology holds to change the drug development process and reduce the
use of animals in research.
One
of their more important avenues
of research has been redesigning and enhancing state -
of - the - art habitat connectivity maps that can be paired with satellite imagery to display the
potential corridors
used by
animal populations to move between both large and small areas.
One
potential reason for this discrepancy is that the laboratory tests
used in
animal models
of the disease do not resemble the clinical assessments given to patients, and thus are not predictive
of human memory performance.
Refine: The
use of methods that alleviate or minimize
potential pain, suffering or distress and enhance
animal welfare for the
animals used.
These ensure that those doing the work are qualified and suitable; that alternatives to
animals are
used wherever possible; that the number
of animals used is minimised; and that any suffering or other harmful effects experienced by the
animals have been weighed against the
potential benefits (to humans or
animals).
«In addition to organ transplants there could also be
potential for
using animal cells, where transplants
of pancreas cells could help the many diabetes sufferers.
More than 3,000 years
of recorded
use, as well as modern clinical research in both humans and
animals, suggest a wide range
of potential applications for BLACK CUMIN SEED OIL ORGANIC - from helping to balance the gut microbiome to benefitting epidermal structure and appearance.
Insofar as we can generalize from these
animal experiments to humans, they provide a
potential rationale for
using low - protein diets to treat cancer patients, and raise the important clinical question
of how to best maintain proper detoxification in these patients.
Researchers looked at Stevia's
potential use as a prebiotic
animal feed supplement, in light
of the 2007 ban on the
use of seven common antibiotics in
animal feed.
«Proponents
of grain - free diets look for the studies that show the negative effect
of excessive refined grains and then apply it to all grains, or they
use research on the
potential adverse effect
of genetically modified wheat on lab
animals and then make sweeping generalizations about the adverse effect
of all wheat on people,» says Katz.
Both make this an apt choice for
animal and nature lovers to
use to discover the
potential of their home theaters.
Get Your Hands Dirty outlines some
of the
potential for
using growing plants and caring for
animals in your school to enhance learning opportunities and raise standards.
Remember that everything you post on social media can be
used for or against you: your political opinion, your favourite books and the frequency
of baby
animal videos are all points based on which your
potential readers are going to judge you.
She
uses a combination
of low - force gentle techniques, modalities and exercises to help each
animal achieve its maximum health
potential.
With such a wide range
of potential careers, there are a number
of methods
used to become an
animal behaviorist.
(FOUR PAWS Press Release) Monday 28th September is World Rabies Day and
animal welfare organisation FOUR PAWS UK is
using it as an opportunity to warn
of the
potential risks posed by the illegal puppy trade.
Extensive effort are made to provide excellent care for
animals used in research, to gain the maximum amount
of information from every
animal used, and to minimize procedures that have
potential for discomfort, distress, or pain.
«
Animal rescue groups play a vital role in improving animal welfare in communities across the country, but many could use a little extra guidance and additional tools to reach their potential,» says Abby Volin, rescue group coordinator for The Humane Society of the United S
Animal rescue groups play a vital role in improving
animal welfare in communities across the country, but many could use a little extra guidance and additional tools to reach their potential,» says Abby Volin, rescue group coordinator for The Humane Society of the United S
animal welfare in communities across the country, but many could
use a little extra guidance and additional tools to reach their
potential,» says Abby Volin, rescue group coordinator for The Humane Society
of the United States.
Using parallel methods
of protection as in humans, pet vaccines initiate defensive immune response, preparing the
animal's body to fight a
potential future infection.
Furthermore, before being
used for a new
animal, the enclosure must be thoroughly cleaned and sterilized to prevent the
potential spread
of disease.
Working with two
of the largest high - kill shelters in the country, HeARTs Speak will provide free digital cameras, lenses, lighting equipment and backdrops, plus a two - day workshop to train shelter employees on how to
use the equipment and take the types
of photographs that get shelter
animals noticed by
potential owners.
You should make your community aware
of the
potential dangers
of some widely
used pesticidal products that, even in commonly found dosages, can damage the nervous systems
of humans and their
animal friends.
Not an approved drug for cats Young, growing
animals due to
potential for cartilage abnormalities
Use with caution in
animals with liver or kidney conditions, or those suffering dehydration Breeding, pregnant or nursing
animals Pets who have a history
of seizures or other central nervous system disorders Pets known to have had an allergic reaction to other quinolones Directions:
Young, growing
animals due to
potential for cartilage abnormalities
Use with caution in
animals with liver or kidney conditions, or those suffering dehydration Should not be
used at high doses in cats (may cause blindness) Breeding, pregnant or nursing
animals Pets who have a history
of seizures or other central nervous system disorders Pets known to have had an allergic reaction to other quinolones and / or sulfonamides Directions:
Only when the body is healthy — do herbs have the greatest healing
potential Do raw food diets compliment the
use of holistic herbs for
animals?
That's the kind
of nonjudgmental tone ASPCA Partnership agency Kentucky Humane Society (KHS)
uses to promote their Courtesy Re-homing Service, a program that empowers pet owners who wish to find a new home for their
animal to connect with
potential adopters.
It is important, however, to always tell your veterinarian if you are
using any over the counter arthritis supplements or herbal supplements on your
animal, because there is the
potential of drug interactions, as well as a thinning
of the blood and / or more predisposition to bleeding if too many medications are
used in combination.
As
animals age there is the
potential for development
of conditions that can make routinely
used anesthesia drugs difficult for their system to handle.