To demonstrate one
potential use of the nanoparticles, the research team used them as advanced catalysts for ammonia oxidation, which is a key step in the production of nitric acid (a liquid acid that is used in the production of ammonium nitrate for fertilizers, making plastics, and in the manufacturing of dyes).
Not exact matches
To demonstrate the
potential for treating lung disease, the researchers
used the
nanoparticles to block two genes that have been implicated in lung cancer — VEGF receptor 1 and Dll4, which promote the growth
of blood vessels that feed tumors.
While on one hand, there is significant
potential in the application
of nanoparticles in enhancing heat transfer for tumor ablation and targeted drug delivery, there is also much promise in improving imaging and diagnostic protocols
using them.
At the state level, Wisconsin legislator Terese Berceau (D - Madison) has asked her state's departments
of Natural Resources, Health and Family Services, and Agriculture, Trade and Consumer Protection to work with her to create a registry
of businesses that make
nanoparticles as a first step toward tracking their
use and
potential health effects.
By applying an innovative theoretical analysis to observations from a first -
of - its - kind experimental setup, LANP graduate student Bob Zheng and postdoctoral research associate Alejandro Manjavacas created a methodology that solar engineers can
use to determine the electricity - producing
potential for any arrangement
of metallic
nanoparticles.
The point was further emphasized in a press release put out by Nature Nanotechnology this week: «These findings suggest that direct and indirect effects
of nanoparticles on cells are equally crucial when considering the
potential risks
of their
use in nanomedicine.»
«The
potential therapeutic value
of this finding is important because we could deliver MIR506 directly to pancreatic cancer cells
using technologies like
nanoparticles and exosomes,» Zhang said.
«RNAi therapies are a unique approach to cancer treatment as they have the
potential to «turn off» the genes» coding for proteins involved in cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director
of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director
of the Clinical Translational Research Division
of the Translational Genomics Research Institute (TGen) in Phoenix, Ariz. «
Using a lipid
nanoparticle, the RNAi drug can be delivered to a cancer cell to block the expression
of specific proteins involved in tumor growth.»
The researchers now plan to tweak the
nanoparticles for direct
use in human patients, working to evaluate the safety
of the method prior to
potential clinical trials.