Sentences with phrase «potential vaccine target»
The epitope where 2D22 binds to the virus may therefore represent a potential vaccine target.
http://science.sciencemag.org/ Not exact matches
To generate a rich source of potential vaccine and drug target candidates, the team identified a set of genes that are more active in certain stages of the parasite life cycle and within the parasite's gut.
H. contortus has become resistant to all major treatments against parasitic worms, so its genome is a good model to understand how drug resistance develops in this complex group of closely related parasites and will also reveal further potential drug and vaccine targets.
The epitope defined by HMAb 2D22 is a potential target for vaccines and therapeutics.
Babayan says potential vaccines should be tested for whether their targets adapt to them in this way.
On the other hand, there was the potential to help inform the development of vaccines and treatments down the road, because the decoy protein could interfere with treatments targeting the critical protein.
«Key benefits of large - scale use of universal over conventional flu vaccines: Mathematical model reveals potential effects of new vaccines that target multiple flu strains.»
The lack of a vaccine or antiviral drugs to combat the Zika virus has scientists scrambling to identify and better characterize potential drug targets.
The vaccines targeted an influenza A H1N1 seasonal flu strain as well as A (H7N9), a virus considered to have the potential to trigger a human pandemic.
In this paper, Kumaraswami said he and his team found a critical target on which to focus for developing a potential Group A Streptococcus vaccine or antibiotic to fight it.
Scientists are also breaking ground with nucleic acid platforms that have the potential to deliver cancer vaccines, for neoantigens and other targets.
In addition, more targeted use of the potential vaccines and drugs that scientists are currently working on intensively could be planned.
Because different proteins are produced in each stage of the microbe's cycle, Plasmodium presents a shifting target for potential vaccines.
These findings add an important and previously overlooked component to the causes of dengue vascular leak, identify a new potential target for dengue therapeutics, and support inclusion of NS1 in dengue vaccines.
Together, these new findings highlight NS1 as an instigator of dengue - associated vascular leak and thus pinpoint a potential target for dengue drugs and component for dengue vaccines.
Her work - published in December 2007 - revealed genes involved in drug resistance and in evading the immune system, giving researchers potential targets for new therapies and vaccines.
«In addition, our method offers the potential to accelerate the development of new vaccines by allowing the efficient evaluation of candidate target antigens.»
Through strategic partnerships with industry and nonprofit organizations, we gain access to a portfolio of priority drugs for testing within our expert focus groups, including checkpoint inhibitors, therapeutic vaccines, innate immune stimulants, targeted therapies, and many other promising treatments and technologies with high therapeutic potential.
The findings should help scientists to better understand the immune system, including autoimmune diseases, as well as provide potential new targets for immunotherapy and vaccine design.
Rationalise drug and vaccine development by providing a systematic catalogue of genetic variation in potential drug or vaccine targets, crucial information for assessing the viability and sustainability of a proposed drug or vaccine.
Studies conducted and supported by NIAID have led to important new discoveries about the microbes that cause NTDs, the identification of targets for potential new drugs and vaccines, and the development of strategies for controlling organisms that transmit NTD - causing agents to humans.
This type of genomic surveillance can provide crucial insights to disease control efforts, while also generating data of fundamental scientific interest, such as potential drug and vaccine targets.
«Seeing the design of this key protein provides a target for a potential vaccine or even a therapeutic drug,» Smith said.