Sentences with word «potentiator»

- A CFTR Potentiator in Patients with Cystic Fibrosis and the G55ID Mutation; Bonnie Ramsey, Seattle Children's Research Institute.

A CFTR Potentiator in Patients with Cystic Fibrosis and the G55ID Mutation; Bonnie Ramsey, Seattle Children's Research Institute.

4 - Hydroxyisoleucine: a novel amino acid potentiator of insulin secretion.

Other functionally distinct compounds are classified as nicotinic anthelmintics, glutamate-gated chloride channel potentiators or macrolides.

Li H et al. (2016) Penetrance of Congenital Heart Disease in a Mouse Model of Down Syndrome Depends on a Trisomic Potentiator of a Disomic Modifier.

This drove Muscle Elements to create a product that delivered full doses of amino acids and nitric oxide potentiators to warrant being the first authentic Amino - Oxide product on the market.

In contains various B vitamins such as thiamine, niacin, pyridoxine, and vitamin B12, along with calcium, chromium, caffeine, and a 5x potentiator blend together with a 5x thermo energetic blend.

When the mother's behavior facilitates the recovery of an existing stress response, she can be viewed as an HPA attenuator; when her behavior retards such a recovery, she can be viewed as an HPA potentiator.

A potentiator called VX - 770, also known as ivacaftor, has proven very effective for the small subset of CF patients with this specific genetic mutation.

In a separate experiment, Gentzsch's team treated the CF cells for two days with a potentiator and a corrector at the same time; this is how a drug would be given to patients.

Scientists also create compounds called «potentiators» to activate the CFTR channels at the cell surface to maintain the proper balance of electrolytes in fluids, including those found inside lungs.

«The potentiator acted like an inhibitor of the corrector compound.

But when they acutely (in seconds) added the potentiator VX - 770, the corrected CFTR protein exhibited a brief increase in function that rapidly waned, a sign that the corrected CFTR protein was losing its ability to function as an ion channel.

Gentzsch found that the potentiator compound chronically destabilized the CFTR protein, and that the destabilization was dependent upon the dose of VX - 770.

However, the vast majority of CF patients have the «transit» mutation and insufficient CFTR proteins at the cell surface; these patients may need a corrector and a potentiator.

That is, the experiments showed that the potentiator cancelled out the intended effect of having a corrected CFTR protein at the epithelial surface.

Synergist — as a potentiator, MSM improves the cellular uptake of vitamins and nutrients, such as all B - vitamins, vitamin A, C, D and E, Coenzyme Q10, selenium, amino acids, calcium, magnesium and many others, and prolongs their lives and potency.