Sentences with phrase «powerful bioinformatic approaches»
This requires the development of powerful bioinformatic approaches that allow prediction of haplotypes from numerous variants, and the classification of haplotypes into functionally related categories, in order to identify those specific sequence variants, or combinations of variants, associated with the disease phenotype.
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By reducing the search space for miRNA binding sites to a 45 -60-nucleotide Ago footprint, HITS - CLIP offers a powerful complementary approach to bioinformatic methods for miRNA binding site prediction.