The pathway, they discovered, contains at least two potentially
powerful drug targets, according to the team leader, CSHL Professor Nicholas K. Tonks.
«New signaling pathway discovered in HER2 - positive breast cancer, and two
powerful drug targets.»
Not exact matches
Previously, only two
targets of artemisinin have been identified, and their correlation with the
powerful parasite - killing effect of the
drug has been questioned.
That raised an intriguing question, because one of the few things scientists already knew about cyclophilin A was that it is the
target of a
powerful immunosuppressant
drug, cyclosporin A.
For
drug designers, the system's
powerful role in regulating cravings, mood, pain, and memory makes it a tantalizing
target.
«The identified proteins may provide
powerful targets for development of synergistic
drugs aimed to accelerate bacterial killing.»
«We think these gold compounds will be a
powerful platform to prepare new tracers, and we're working to improve the system and to identify promising, clinically - relevant
drug targets,» he said.
These technologies are particularly
powerful when looking for changes in concentrations of multiple
targets under specific conditions, such as following a vaccine administration, infection, or a
drug treatment.
Scientists using a
powerful mathematical tool previously applied to the stock market have identified an Achilles heel in HIV that could be a prime
target for AIDS vaccines or
drugs.
our stroke research, we will soon be able to find a gene within the type 2 diabetes locus we have identified and use this gene to identify
powerful new
drug targets.»
By uncovering the precise cellular mechanisms of nicotine's effect, this study suggests new and more precise
targets for
drugs designed to block this
powerful craving.
Knowledge of the amount of
drug that is available to bind
targets inside cells provides a
powerful tool for compound selection in early -LSB-...]
Founded in 2010 by Drs. Stig K. Hansen and Daniel A. Erlanson, Carmot has built and optimized this
powerful platform to identify superior
drugs for validated
targets with significant market potential such as GLP - 1R / GIPR for Type 2 diabetes and NEMO / IKK for cancer and inflammation, and which have been refractory to traditional discovery approaches.
By identifying novel molecular
targets and potential new
drugs, this
powerful technological structure will contribute significantly to groundbreaking research towards the development of new anti-cancer therapies.
This is obviously an oversimplification, Dr. Celi says, but the demonstration that adults have brown fat that can be activated is, nevertheless, «
powerful proof of concept» that the tissue could be a
target for obesity - fighting
drugs or even environmental fat - fighting strategies.
Physicians and researchers noted that insights will also lead to the development of
powerful drugs to
target DNA errors that cause cancer and highlight ways in which the disease can be prevented.