As
a powerful tumor suppressor, p53 turns on genes that either halt cell division to allow time for repair of damaged DNA or, when all rescue attempts prove futile, to prevent cells with genetic defects from dividing, as this would fuel the development of cancer.
LA JOLLA, CA — A tightly controlled system of checks and balances ensures that
a powerful tumor suppressor called p53 keeps a tight lid on unchecked cell growth but doesn't wreak havoc in healthy cells.
Mice that are unable to fully activate
the powerful tumor suppressor p53 are resistant to high doses of radiation.
LA JOLLA, CA — A tightly controlled system of checks and balances ensures that
a powerful tumor suppressor called p53 keeps a tight lid on unchecked cell growth but doesn't wreak havoc...
Now, researchers studying mice have found one of the most
powerful tumor suppressor genes yet — animals lacking it have a startling 50 % chance of developing cancer.
Not exact matches
Now, results of a new study by Johns Hopkins Kimmel Cancer Center scientists suggests a
powerful role for the protein in normal breast cells, acting as a
tumor suppressor that halts abnormal cell growth.