All the participants were part of the Long Term Intervention
with Pravastatin in Ischaemic Disease Trial and had had a heart attack or been admitted to hospital for unstable angina in the preceding three to 36 months.
The use of lipophilic, or fat - soluble, statins such as simvastatin and atorvastatin was associated with a reduced risk of Parkinson's, while no such association was found for hydrophilic, or water - soluble, statins such
as pravastatin and rosuvastatin.
Results: Simvastatin, but
not pravastatin, reduced CSF levels... of phospho - tau - 181 (p - tau181) in all subjects.
I just have a quick question, my current Doc wants me to go
on pravastatin but with one autoimmune disease I don't want any chance of another (there's a rare autoimmune myopathy linked to statin drugs).
The Progeria Research Foundation's lonafarnib trial ended in 2010, but the foundation is now monitoring 45 children from 24 countries who are taking the drug, as well as the cholesterol
drug pravastatin and zoledronate, which prevents fractures.
Fluvastatin = Lescol, Lescol XL Lovastatin = Mevacor, Altocor Mevastatin Pitavastatin = Livalo,
Pitava Pravastatin = Pravachol, Selektine Rosuvastatin = Crestor Simvastatin = Zocor, Lipex Simvastatin + Ezetimibe = Vytorin Lovastatin + Niacin extended - release = Advicor Atorvastatin + Amlodipine Besylate = Caduet How Do Statin Drugs Work?
They found that people with the gene variant had the highest risk of side effects when they were given a statin called simvastatin, but this risk was much lower when they
took pravastatin.
In the years following, a posse of other cholesterol fighters joined simvastatin to create what would become a $ 20 billion — plus annual market:
pravastatin (Pravachol), fluvastatin (Lescol), atorvastatin (Lipitor), cerivastatin (Baycol), rosuvastatin (Crestor) and finally pitavastatin (Livalo).
Recently two phase II clinical trials were initiated by treating HGPS patients with Farnesyltransferase inhibitors (FTIs) and / or the combination of Zoledronate and
Pravastatin to prevent or delay the gravest infringements of the disease.
Methods: We measured levels of cerebrospinal fluid (CSF) AD biomarkers following 14 weeks of treatment with simvastatin (a CNS permeant statin; n = 10) at 40 mg / day or
pravastatin (a CNS impermeant statin; n = 13) at 80 mg / day in hypercholesterolemic subjects without dementia.
If successful I could then stop
the pravastatin and see if my lipids remain low.
The review also identified that 10 mg per day of policosanol produced the same cholesterol - lowering effect as the same dose of statin drugs such as simvastatin and
pravastatin.
You could be taking Simvastatin, Lipitor, Crestor,
Pravastatin, Atorvastatin, or Zocor, and it won't matter.