Sentences with phrase «pre-existing immunity to it»
H7 subtypes in general can become more transmissible to humans, but the N9 element of H7N9 is newly evolved, and, if it became more transmissible, humans would have no pre-existing immunity to it.
http://discovermagazine.com/ Not exact matches
Identification of pre-existing adaptive immunity to Cas9 proteins in humans. bioRxiv.org.
The trial conducted at the WRAIR Clinical Trial Center in Silver Spring, Md., is assessing the impact of pre-existing flavivirus immunity in volunteers who had been vaccinated against yellow fever or Japanese encephalitis — both viral cousins to Zika — prior to receiving ZPIV.
Cholera is now endemic in Haiti, and many people have had exposure to cholera bacteria and may have some pre-existing level of immunity.
Many factors contribute to the risk for DHF, but one of the most important factors is pre-existing immunity from an earlier DENV infection.
Vaccine development for DENV is challenging in that the vaccine must induce long - lasting immunity against all four DENV serotypes (DENV1 - 4), as pre-existing immunity against a heterologous serotype may contribute to severe dengue disease (DHF / DSS).