Sentences with phrase «precise changes in»

In addition to knocking out genes, the same method allows scientists to engineer precise changes in a particular gene.

ROB STEIN, BYLINE: Scientists have recently developed powerful new techniques that let them make very precise changes in DNA.

And very precise changes in the aim and strength of the light could affect the electrical waves.

Bruneau's team is now researching the precise changes in gene expression and protein levels caused by a mutation in TBX5.

CRISPR - Cas9 is an experimental gene editing technique used to make precise changes in DNA.

Farren Isaacs of Yale University led the team that this week proves it is possible to make numerous and very precise changes in the genome of living cells.

The specificity of this DNA cutting activity has made CRISPR - Cas the darling of gene therapy researchers, who have modified it to make precise changes in the genomes of cultured cells, laboratory animals, and even humans.

So, I'll just say a little more about why yeast; which is, over the decades, yeast molecular biologists have devised so many powerful tools that allow you to make very precise changes in yeast, in their DNA; exquisite control, where you can change a single base that you want in a particular place, you can put a whole gene in, take a whole gene out, swap genes etc..

For nearly five years, researchers have been wielding the molecular scissors known as CRISPR / Cas9 to make precise changes in animals» DNA.

JaP, I'm pretty sure that Isaac Held's comments related to what we expect on average, not a claim that a change in radiative forcing will produce a precise change in temperature at all locations at any time.

Not exact matches

Make some precise changes, with this in mind, and you'll start to see the benefits, guaranteed.

Despite this and other authoritative warnings about the dangers of climate change, Mr. Pruitt persists in pointing to uncertainty about the precise extent of humanity's contribution to the problem as a basis for resisting taking any regulatory action to help solve it.

While there is no precise data about how heroin production in Mexico has changed in recent years, evidence suggests the drug's cultivation, and competition between gangs over it, has risen in Mexico, and in Guerrero in particular.

Legal experts, speaking on a not - for - attribution basis because precise measures have not been announced, said one possibility is the government might change the Competition Act to say that «abuse of a dominant position» would include «exploitative pricing» or, in effect, charging too much.

In our leadership work we show our leaders how to transmit a precise type of leadership impact to meet different business outcomes by using various specific postures and facial expressions that prime your behaviors to achieve the particular business outcome, as well as signal to others how your behaviors will change outcomes.

It didn't just randomly explode, rather it expanded in such a precise manner that an infinitesimal change would have rendered a universe where matter was so spread out no formation of stars could have possibly occurred.

But whatever the precise shape of such changes might turn out to be, the crucial fact is that they were forthrightly acknowledged by the primates at Egypt as necessary in some form.

The fossil record which shows millions of years of stable species, then an explosion of necessarily mutations, all occurring at the precise necessary time required for complex organisms to develop, and ALL escaping fossilization «the sudden appearance of most species in the geologic record and the lack of evidence of substantial gradual change in most species — from their initial appearance until their extinction — has long been noted, including by Charles Darwin who appealed to the imperfection of the record as the favored explanation» — Wikipedia

People have rejected theism because they held untenable the idea of a mind not subject to change or to interaction with other beings, or a mind omnipotent in the sense that its power was all the power in existence, or a mind having precise knowledge of details of the future (or of all times from the standpoint of eternity), or a mind creating a first state of the cosmos at a finite time in the past, or knowing all suffering although it did not itself suffer, or an all - embracing mind which in no sense could be identified with the universe, or one which could in every sense be identified with it.

Normally in such cases he can only change with the Church's whole consciousness of its belief, if such a change really takes place in respect of a more precise discernment of the fundamental moral guiding principles or of certain applications of these to new situations.

He's kept a precise record of his religious temperature and informs God of every change in degree.

-- The Earth was formed by this giant explosion which took place millions of years ago and somehow ended up in this perfectly rotating planet that has perfectly precise, repeatable days, months and years and rotates at the perfect angle so as to enable defined changes in climate and weather to have predictable seasons.

Because it is calculated according to a lunar rather than a fixed calendar, its precise dates change from year to year, and it can begin at different times in different parts of the world.

We tend to repeat customary actions unaware that when we do today what we did yesterday we actually do something different since in the interval both we and our environment have changed; unaware also that we now do without conscious definition of purpose and method what was done yesterday with specific ends in view and by relatively precise means.

But I think it is also evident that no hope exists of pinpointing the precise number of changes of habit that are necessary and sufficient for a significant shift in personal identity, just as it is impossible to say how few hairs on a man's head constitutes baldness.

Not only do the individualities influence the change of the images; it would be an important problem of the philosophy of history in the study of the history of religions to search out the influences, the categories, through which a precise «relative a priori» — to use Simmel's expression — acts upon the shaping of the «images»: national, tribal, race, class, sexmembership.

The precise impact of the changes to the Telecom Act remains unclear at this point in time.

How Millennials Are Changing The Wine Industry: While the precise dates governing the birth years for the biggest generation in history known as millennials vary, (somewhere between 1976 and 2004), there is no dispute that they love their wine

Therefore, the precise amounts of honey consumed in 1995 were generated from an analysis of changes in food - commodity groups (25).

I know it doesn't seem like a huge change to make if you're used to it, but it can be hard to switch over to measuring in a whole new way and it can be tough to make sure the measurements are exact in grams / ounces (at least in my experience — for instance I keep having to spoon out extra flour out of the bowl if I added too much... it definitely takes a learning curve to be precise).

NASCAR's introduction of a new inspection system featuring 17 cameras that examines cars in a more accurate and precise manner has changed the game.

Another narrow Super Bowl loss and a whole lot of talk about dysfunction in the locker room and in the front office isn't going to change the fact the Patriots are among the most consistent teams in football, and they should be viewed as such until the precise moment it's proven otherwise.

I don't recall it being any different when I changed to a public middle school (in New York, we called it an «intermediate school» — I.S. 61, to be precise) in the sixth grade.

And even if the information could be more precise and predictive than it currently is, social science research indicates that knowing this information might not result in many people changing their lifestyle or behaviour.»

Jessica Wentz, associate director and a postdoctoral research fellow at Columbia University's Sabin Center for Climate Change Law, wrote in a blog post that the phrasing shift is more technically precise and likely addresses concerns about how far an agency needs to go in calculating emissions.

CRISPR — Cas9 (or CRISPR, for short) has given scientists a powerful way to make precise changes to DNA — in microbes, plants, mice, dogs and even in human cells.

«Studying these fingerprints in detail requires very precise measurements of the wavelength, or colour, of the light emerging from the atmospheres of these stars» says Dr Matthew Bainbridge, who has been working on the detailed analysis techniques needed to detect the tiny changes expected.

Revealing the precise structure of the serotonin transporter holds tremendous promise for the development of life - changing drug treatments for these diseases,» said Eric Gouaux, Ph.D., senior scientist in the Vollum Institute at OHSU, National Academy of Sciences member, and Howard Hughes Medical Institute Investigator.

Help the reviewer: Before your response, repeat verbatim the essence of the comment; in your response, include the precise location of any change that resulted from the comment.

In associated commentaries published online this week in Nature Reports Climate Change, several scientists criticize the precise thresholds set, although they laud the efforIn associated commentaries published online this week in Nature Reports Climate Change, several scientists criticize the precise thresholds set, although they laud the efforin Nature Reports Climate Change, several scientists criticize the precise thresholds set, although they laud the effort.

I'm keen to find out the precise sequence of changes to OLs and myelin during learning and whether these changes are needed more in some parts of the brain than others, which might shed light on some of the mysteries still surrounding how the brain adapts and learns throughout life.»

Using this imaging technology, we may be able to capture more precise and objective measurements of olfactory dysfunction and better understand how changes in these sensory neurons relate to overall health and neurodegeneration in the brain.»

As the iron changed from solid to molten, they measured the temperature by noting a change in how X-rays were diffracted — a faster, more precise method than the simple visual techniques used in older experiments.

Where previous estimates were drawn from a range of mostly long - run models that looked at century - long changes, we instead focused on a precise definition and current starting point, and other factors which matter far less in the long term, but a lot if the goal is much closer.

The carbon in layers of algae from the bottom of a Japanese lake will help reveal the precise dates of historical climate change and human migrations

Pounds writes in an e-mail that climate change has caused greater day - to - day variations in precipitation at Monteverde, something the isotope method isn't precise enough to measure.

In another experiment, he measured the frequency of an optical transition in cesium atoms (a change in their state that absorbs or emits light at a precise frequency) using a mode - locked laser to span the difference in frequency between two CW laserIn another experiment, he measured the frequency of an optical transition in cesium atoms (a change in their state that absorbs or emits light at a precise frequency) using a mode - locked laser to span the difference in frequency between two CW laserin cesium atoms (a change in their state that absorbs or emits light at a precise frequency) using a mode - locked laser to span the difference in frequency between two CW laserin their state that absorbs or emits light at a precise frequency) using a mode - locked laser to span the difference in frequency between two CW laserin frequency between two CW lasers.

The model is designed so that they can embed it within coarser global climate models — a combination that results in precise simulations of hurricanes in the context of a globally changing climate.

Nisbet's prior research examining public opinion about climate change and energy insecurity also revealed for science communicators that understanding the public in more precise ways than partisanship or ideology allowed for improved outreach.

However, the precise nature of that role is undergoing a visible change, not only because of the new synthetic methods and technologies now available to the synthetic and medicinal chemist, but also in several key areas, particularly in drug metabolism and chemical toxicology, as chemists deal with the ever more rapid turnaround of testing data that influences their day - to - day decisions.