Not exact matches
Many researchers, including Van Trung Chu, Klaus Rajewsky and Ralf Kühn, are seeking to promote the HDR repair pathway to make
gene modification in the laboratory more
precise in order to avoid editing errors and to increase efficiency.
Genome editing technology enables
precise modification of individual protein coding
genes, as well as noncoding regulatory sequences, enabling the elucidation of functional effects in human disease relevant cellular systems.
Two newer
gene - editing methods — zinc finger nucleases, used since the late 1990s, and TALENs, first described in 2011 — allowed more
precise modifications, he says, «but there was a real art and skill required, and only a handful of labs could do those.»