Sentences with phrase «precise targets in»

With an estimated 1 billion people worldwide suffering from some form of brain disorder, he argues, there is a very real need for new approaches, including optogenetics, to reveal more precise targets in the brain.

Not exact matches

And in addition to the usual service fees, T - Mobile sees the possibility of selling TV ads using targeting technology that is more precise than what is possible through cable networks.
Small businesses can officially stop worrying about how to reach every consumer that could possibly want their goods and services: Geo - precise marketing and precision targeting is now leading the pack in consumer marketing.
«Data and insight that comes directly from patient records — real - world evidence — is transforming how pharmaceutical and life science companies develop more precise, targeted therapies,» said Cota CEO John Hervey in a statement.
More precise targets on the size and the valuations will be determined after the company begins talks with investors in coming weeks, said the people, who spoke on the condition of anonymity.
In his two slow - motion practice swings, Crane dialed in the precise technique required for a peeler by delaying the release of his wrists at impact and then holding his finish so that the butt end of the shaft points away from the targeIn his two slow - motion practice swings, Crane dialed in the precise technique required for a peeler by delaying the release of his wrists at impact and then holding his finish so that the butt end of the shaft points away from the targein the precise technique required for a peeler by delaying the release of his wrists at impact and then holding his finish so that the butt end of the shaft points away from the target.
If Megatron's footwork in and out of his cuts is not as crisp as was that of, say, Raymond Berry, the obsessively prepared, fanatically precise Baltimore Colt and favorite target of Johnny Unitas, that's not necessarily a problem — according to... Raymond Berry.
First, the pessimistic one outlined by Marshall Ganz in the early 1990s, suggesting that ever more precise targeting of voters will narrow the electorate by leading campaigns to focus their efforts on fewer and fewer people leaving others outside the process.
Does the increasingly precise and individualized targeting possible today, then, expand the electorate, as some have suggested, or does it in fact narrow it, as others have argued?
It could even see us altering the ecosystem in a precise, targeted way.
These results significantly advance understanding of how cancer cells are made to move during metastasis and may provide more precise targets for drugs to stop cancer metastasis in patients where there are oncogenic mutations.
This case demonstrates the importance of precise diagnosis of the molecular causes of an illness in enabling targeted, personalized treatment.
Neurons formed later are much more precise in their targeting.
He notes, for instance, that the TI stimulated patches several millimeters across in the rodent's brains — far larger than the precise spots targeted by implanted electrodes.
In his new book, Venter introduces readers to a future of precise biological engineering, guided by DNA and targeted to create life forms never before thought possible.
TBK1has been shown to target certain proteins involved in mitosis; however, its precise role in this process is not understood.
Axons in particular can travel spectacular distances to reach astonishingly precise targets.
«Discovering that these protein interact with other signals in preformed complexes gives us more precise targets for medication development.»
Each strain of phage is highly targeted and has evolved to home in on specific bacteria, which means a precise match between prey and predator is necessary for any phage - based treatment to be effective.
The researchers will now work to better understand what goes wrong in GRN - mutated cells, as well as identify precise molecular targets that could then be used for drug screens.
CRISPR is an enzyme that scientists have been able to «program» using targeting RNA in order to cut DNA at precise locations that the cell then repairs on its own.
The research group focused on the precise role of chloroplast - targeted autophagy in the plant survival strategy under low - energy stress.
It is a confederation of non-governmental organisations and pressure groups lobbying for a ban on producing and deploying fully autonomous weapon systems — where the ability of a human to both choose the precise target and intervene in the final decision to attack is removed.
«Biologists uncovers a genetic mechanism that could enhance yield in cereal crops: Precise regulation of plant hormones in early reproductive development as a target for yield increases.»
In doing so, they hope to contribute to the development of more effective, precise and target - driven therapies to prevent heart disease in womeIn doing so, they hope to contribute to the development of more effective, precise and target - driven therapies to prevent heart disease in womein women.
Schuster and Peggy Gerullis made the discovery by first training fish to hit targets ranging in height from 20 to 60 centimeters from a precise location.
IGRT is the process of using frequent imaging, typically performed in the treatment room prior to radiation delivery, throughout a patient's course of radiation therapy treatment to improve localization of the target and normal structures, which allows for more precise and accurate radiation delivery.
Newer, precise methods which target the dents in cancer's armoury provide fresh opportunities for better treatments to help more people survive the disease.
To conduct the study, Salas and her colleagues from the Department of Psychiatry and Behavioral Sciences and the Department of Physical Medicine and Rehabilitation used transcranial magnetic stimulation (TMS), which painlessly and noninvasively delivers electromagnetic currents to precise locations in the brain and can temporarily and safely disrupt the function of the targeted area.
When coexpressed with a recombinase, these intracellularly expressed ssDNAs target specific genomic DNA addresses, resulting in precise mutations that accumulate in cell populations as a function of the magnitude and duration of the inputs.
«This will allow researchers to target an expanded range of sites in a variety of genomes, which will be useful for applications requiring highly precise targeting of DNA sequences.»
After a good spam campaign, with a mix of pharmaceutical messages for a client, paid for in batches of a million and sent to a cheap, inferior list of addresses — and phishing messages for your personal profit, sent to a more precise, targeted list — you can come back to the market with more data to sell, and more money with which to buy work and data from the others.
Future studies investigating how neural signals change in response to microstimulation (and how these changes vary with the precise targeting of the stimulating electrode) will be critical for increasing our understanding, not only of the physiological signatures of microstimulation, but also the microcircuit dynamics underlying memory.
Scientists can design the precise letter sequence they want to target, and use CRISPR to home in on that specific part of the genome.
Critically, gesicles do not result in persistence of the Cas9 endonuclease, which in turn reduces the chances of off - target effects and provides precise control of the dose and timing of gene editing.
The host star is bright (V = 11.2, J = 9.1) and so may be a good target for precise radial velocity... ▽ More We report the discovery of a Neptune - size planet (Rp = 3.0 Re) in the Hyades Cluster.
LA JOLLA, CA — A new method for rapidly solving the three - dimensional structures of a special group of proteins, known as integral membrane proteins, may speed drug discovery by providing scientists with precise targets for new therapies, according to a paper published May 20 in Nature Methods.
Genome editing techniques allow within one cell, the precise modification of targeted DNA sequence in a genome of interest by insertion, deletion or replacement.
Knowing the precise shape of these complex protein structures is enormously valuable in guiding the development of targeted drugs.
While it's extremely precise, it occasionally modifies DNA at similar sites elsewhere in the genome instead of the target gene.
The accurate asteroseismic determinations now available for large number of stars in the Kepler fields can be used to check and calibrate surface gravities that are currently being obtained spectroscopically for a huge numbers of stars targeted by large - scale spectroscopic surveys, such as the on - going Large Sky Area... ▽ More Asteroseismology allows for deriving precise values of surface gravity of stars.
We can envision that DAXX can serve as a precise prognostic marker in PCa and that tissue - specific shRNA delivery targeted against DAXX can be employed in the treatment of metastatic prostate cancer in patients, in particular if we discover, through additional studies, that DAXX is a marker for lethal PCa in humans.
In the meantime, our experience to date suggests that precise genome editing of putative targets in primary cell systems is possible, offering more human disease relevant systems than conventional cell lineIn the meantime, our experience to date suggests that precise genome editing of putative targets in primary cell systems is possible, offering more human disease relevant systems than conventional cell linein primary cell systems is possible, offering more human disease relevant systems than conventional cell lines.
Amplified Luminescent Proximity Homogeneous Assay Screen (AlphaScreen) AlphaScreen is a versatile assay technology developed to measure analytes using a homogenous protocol that enables sensitive and precise interrogation of signaling pathways, receptors, enzymes and kinase targets, in a cell - based format.
From on - chip DNA analyzers in clinical settings to high performance computing at the forefront of genomic research, Arm helps make medicine targeted, precise, and personal.
They also acknowledged that it has been controversial and that this manuscript aims to address the two proposed models in a precise and targeted manner.
The Power Zone and Power Line were introduced to work in concert with the high density dome and serve as a «visual guideline» for precise cuing and targeting areas which will produce the greatest returns.
In the future, he adds, a better understanding of the overlap between the two conditions could open the door to more precise diagnoses, and therefore more targeted treatment.
Over the years, I've perfected and modified the class, based on experience and current knowledge, resulting in an evolution of the class that has become more precise and targeted
By placing this ad and enabling precise geo - targeting, you will be sure that it is seen by all the people who are currently in Central Park and are using their devices.
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