National Cancer Institute and ECOG - ACRIN announce the July 2015 opening of the NCI - MATCH / EAY131 trial, a multi-arm phase II
precision medicine study that seeks to determine whether targeted therapies for people whose tumors have specific gene mutations will be effective regardless of cancer type.
July 7, 2016 UChicago to support NIH million - person
precision medicine study The University of Chicago is one of three Illinois academic institutions that will work together to help launch President Obama's Precision Medicine Initiative (PMI) Cohort Program to enroll 1 million or more participants in a national research effort designed to find better ways to prevent and treat disease based on lifestyle, environment and genetics.
A new
precision medicine study aims to push leukemia and lymphoma survival rates ever higher while reducing side effects.
The All of
Us precision medicine study gets a $ 60 million increase, to $ 290 million.
Not exact matches
The National Institutes of Health said today that it's launching a huge research
study with the aim of making
precision medicine available to people of all backgrounds.
Additionally, the agency would continue efforts to advance
precision medicine and cancer genomics in support of the Million Veteran Program (MVP), which aims to collect blood samples and health information from one million veteran volunteers to
study how genes affect health.
Scientists are bringing
precision medicine to rheumatoid arthritis for the first time by using genetic profiling of joint tissue to see which drugs will work for which patients, reports a new Northwestern Medicine multi-sit
medicine to rheumatoid arthritis for the first time by using genetic profiling of joint tissue to see which drugs will work for which patients, reports a new Northwestern
Medicine multi-sit
Medicine multi-site
study.
«Gene therapy restores hearing in deaf mice: Proof - of - principle
study takes a step toward
precision medicine for genetic hearing loss.»
The Coriell
study is committed to advancing the
precision medicine discussion by aligning with progressive institutions, including the United States Air Force Medical Service, and sharing noteworthy data.
The
study involved 58
precision medicine treatment arms and 293 that did not.
Professor Johann de Bono, Regius Professor of Cancer Research at The Institute of Cancer Research, London, and Consultant Medical Oncologist at The Royal Marsden NHS Foundation Trust, said, «Our
study identifies, for the first time, genetic changes that allow prostate cancer cells to become resistant to the
precision medicine olaparib.
Study co-leader Wyndham Wilson, M.D., Ph.D., NCI Center for Cancer Research, added, «This is the first clinical study to demonstrate the importance of precision medicine in lymphomas.&r
Study co-leader Wyndham Wilson, M.D., Ph.D., NCI Center for Cancer Research, added, «This is the first clinical
study to demonstrate the importance of precision medicine in lymphomas.&r
study to demonstrate the importance of
precision medicine in lymphomas.»
The emphasis now is to store samples from almost every major
study with correlative science in mind, and this is essential if we are to understand disease biology, mechanism of response and resistance to therapy in the era of targeted therapy and
precision medicine.»
In another
study representing the first time
precision medicine has been applied to feline health, Lyons and her team used whole genome sequencing and the 99 Lives consortium to identify a lysosomal disorder in a 36 - week - old silver tabby kitten that was referred to the MU Veterinary Health Center.
«This is how we can start thinking about
precision medicine in action,» said the
study's senior author, Alice S. Chen - Plotkin, MD, an assistant professor of neurology at Penn. «We found that a relatively common genetic variation can both serve as a biomarker for and influence the disease course of Parkinson's patients.
Matthew J. Ellis, MD, PhD, said the research, presented at the San Antonio Breast Cancer Symposium, is a step toward
precision medicine, allowing scientists to
study tumors from patients whose treatment regimens are well - documented.
«Our research shows a new link between energy metabolism and inflammation, as well as giving early insights into the fundamentals of
precision medicine regarding the variation of the lipidome among individuals,» said Victor Darley - Usmar, Ph.D., Endowed Professor of Mitochondrial Medicine and Pathology at UAB and a co-investigator on th
medicine regarding the variation of the lipidome among individuals,» said Victor Darley - Usmar, Ph.D., Endowed Professor of Mitochondrial
Medicine and Pathology at UAB and a co-investigator on th
Medicine and Pathology at UAB and a co-investigator on the
study.
«The
study represents a clear breakthrough in
precision medicine, as this molecule only kills the cancer cells that express the cancer - causing gene — not healthy cells.
The
study, appearing in the New England Journal of
Medicine, could lead to tailor - made treatment plans for aplastic anemia patients as part of the emerging precision medicine m
Medicine, could lead to tailor - made treatment plans for aplastic anemia patients as part of the emerging
precision medicine m
medicine movement.
The cancer moonshot has begun to change that, he said, citing NCI's cloud - based Genomic Data Commons, a data repository meant to encourage researchers on different
studies to share cancer genomic data to advance
precision medicine.
«Human chronobiome»
study informs timing of drug delivery,
precision medicine approaches.»
This
study is good example of a
precision medicine themed approach to showing how a mechanistic understanding of the differential gene expression can yield biomarkers that can be used for early detection of disease, as well as potential therapeutic targets.
These
studies allow the construction of robust in vitro human disease models, and also provide a path towards
precision medicine and therapeutic genome editing.
Both have strong experience in
studying the contributions of genetic variation to disease, and they will help to lay the foundations of understanding needed for
precision medicine... more
«This
study is an important step towards developing
precision medicine for at - risk and understudied minority populations,» Burchard said, «But the current lack of genomic data from these populations highlights the urgent need for a dedicated national effort to prioritize diversity in research.»
Based on the results of multiple
studies, Mylotarg was restored to the market in September, and researchers worldwide are pursuing a
precision -
medicine approach — targeting the drug to patients most likely to benefit — based on Meshinchi and colleagues» results.
The difference in expression patterns of individual cancers observed in the
study strongly reinforces the need for personalized cancer treatment based on
precision medicine.
NIMML researchers employ advanced computational tools in combination with experimental and clinical
studies to capture variation and diversity of immune responses, and develop safer, more - effective
precision medicine treatments for infectious and immune - mediated diseases.
The
study, published in the Journal of Biological Chemistry, is a step forward in creating
precision medicine approaches to diabetes prevention and treatment.
Researchers are hopeful that proteogenomics, the integrated
study of proteomics and genomics, may improve our ability to prevent, diagnose, and treat cancer at the molecular level using
precision medicine.
«
Precision medicine means nothing without
precision diagnosis, and we can now provide
precision diagnosis,» said
study lead author Anne Berg, of the Stanley Manne Children's Research Institute at Lurie Children's Hospital of Chicago.