Sentences with phrase «precision oncology»

Scientists with molecular and computational backgrounds are needed to move the growing field of precision oncology forward.

In the growing field of precision oncology, researchers with molecular and computational backgrounds are needed more than ever.

Dr. Mody is leading a clinical trial investigating the role of next generation sequencing (NGS) in precision oncology for developing novel biomarkers and therapeutic targets against refractory childhood cancers.

By expanding on earlier successes in cancer genomics, partnering with patients nationwide who participate in NCI - sponsored clinical trials, and extending precision medicine principles into basic science research and biomedical information technology activities, the PMI ® is enabling NCI to advance precision oncology more quickly and efficiently than originally planned or anticipated.

«This study documents the strong potential of Watson for Genomics to help clinicians scale precision oncology more broadly,» said Vanessa Michelini, Watson for Genomics Innovation Leader, IBM Watson Health.

Our groundbreaking Pediatric Mi - Oncoseq Program is an internationally known precision oncology program focusing on the genetic analysis of pediatric cancer patients including in children with malignant brain tumors, and determines whether targeted treatments may be available based upon their personalized tumor genomic sequencing profiles.

The Seattle conference tackles the future of functional precision oncology.

Dr. Mody's primary research interest includes use of precision oncology approach for designing innovative clinical trials for refractory childhood cancers.

By Murali Prahalad of Epic Sciences — A curious problem arises for each new precision oncology therapeutic with a companion diagnostic: Many predicted responders exhibit primary resistance.

As part of its push toward precision oncology, the company announced early last year that it would spend $ 1.03 billion to buy a 56.3 % stake in Cambridge, Massachusetts - based Foundation Medicine, a company that uses genetics to help select drugs for cancer patients.

Overall, this is a very exciting time for cancer research, as global sequencing efforts mean we are advancing towards precision oncology.»

Our research is driven by a distinctive scientific and clinical strategy focused on precision oncology — understanding how cancer develops on a genomic level and developing drugs that hone in on those targets.

«DarwinOncoTreat and DarwinOncoTarget may provide an entirely novel precision oncology - based diagnostic platform for patients who either have no actionable genetic alterations or who have not responded to, or have relapsed, following targeted or traditional therapies,» says Mahesh M. Mansukhani, MD, medical director of the Laboratory of Personalized Genomic Medicine.

Still, the frustrations in creating a consistently effective immunotherapy led one leading cancer researcher to refer this month to the «precision oncology illusion.»

Michael Berger, PhD, is an Associate Director of the Marie - Josée and Henry R. Kravis Center for Molecular Oncology at Memorial Sloan Kettering Cancer Center, a multidisciplinary initiative to promote precision oncology through genomic analysis to guide the diagnosis and treatment of cancer patients.

These initial findings have paved the way to expand the program into a more comprehensive pediatric precision oncology program that researchers expect to launch in 2016, which will include offering sequencing to pediatric cancer patients diagnosed at other hospitals.

Our approach in precision oncology showed its greatest promise in these difficult to treat patients — 80 percent of our study patients had relapsed or refractory disease, and those are the ones who benefited most from our study.»

The Harvard Business School Kraft Precision Medicine Accelerator is working with the MMRF and other cancer partners to harness the potential of master protocols in precision oncology.

Breakthrough approach to functional precision oncology and rapid cancer drug discovery is covered by Seattle Business Magazine Editor in Chief Leslie Helm.

«This platform has tremendous potential to advance precision oncology, where we can use a patient's tumor DNA to really tailor therapy, but we have to be really rigorous about the science of developing the platform,» agrees Carol Bult, director of the PDX / Cancer Avatar Program at the Jackson Laboratory.

In addition, the company collaborates with biopharmaceutical companies in the development of companion diagnostic tests and technologies for various cancer therapies, helping to realize the promise of precision oncology.

At the German Cancer Research Center, (Deutsches Krebsforschungszentrum, or DKFZ) in Heidelberg, scientists working in precision oncology are also taking full advantage of advances in genomic technology.

At Weill Cornell, Imielinski is participating in the precision oncology effort, which will sequence tumor DNA to match patients to particular therapies.

A fascinating example is our work on genotype - specific vulnerability and resistance of tumours to targeted drugs in our precision oncology project.

The PMI ®'s $ 70 million in funding for NCI is being used to advance the field of precision oncology.

Diagnosed with chronic myeloid leukemia in 2007, she benefited from the precision oncology drug Gleevec.

In addition, U-M is internationally renowned for leadership in precision oncology, using genetic sequencing to effectively target and treat cancer at an individualized level.

Many scientists now believe that — complementing its initial focus on mutated genes — precision oncology must now also address the activity of otherwise normal proteins and molecular pathways that are ultimately responsible for cancer cells» malignant behavior.

Current clients include individual patients, pharmaceuticals and cancer research institutions seeking to find solutions for unmet needs in precision oncology.