Sentences with phrase «preclinical development of»
Researchers at the Sanford Consortium for Regenerative Medicine have broad scientific goals in basic and preclinical research, as well as preclinical development of discoveries.
http://www.sanfordconsortium.com/
Building on his Ph.D. research developing magnetic nanoparticle tracers for Magnetic Particle Imaging (MPI), he co-founded LodeSpin Labs LLC where he led the preclinical development of the first long - circulating blood pool MPI tracer.
Preclinical Development of Ipilimumab and Nivolumab Combination Immunotherapy: Mouse Tumor Models, In Vitro Functional Studies, and Cynomolgus Macaque Toxicology.
Moderna will fund and be responsible for discovery and preclinical development of product candidates, with the aim of delivering one Investigational New Drug (IND) application - ready molecule for each of the two programs.
These forward - looking statements are based on management's current assumptions and expectations and involve risks, uncertainties and other important factors, specifically including those relating to Lexicon's ability to successfully conduct preclinical development of its drug candidates and advance such candidates into clinical development, achieve its operational objectives, obtain patent protection for its discoveries and establish strategic alliances, as well as those relating to manufacturing, the regulatory process, intellectual property rights, and the therapeutic or commercial value of its drug candidates, that may cause Lexicon's actual results to be materially different from any future results expressed or implied by such forward - looking statements.
Hua's extensive work in Krainer's lab, in collaboration with Ionis, led to the identification and preclinical development of nusinersen, a snippet of modified RNA called an antisense oligonucleotide that intervenes in the splicing process to ensure that SMN2 expresses the full - length SMN protein.
Not exact matches
The first move sets Takeda up to work on development of FIN - 524, a preclinical therapy that contains cultured bacteria strains and which could theoretically be used to treat gut diseases.
Through a rigorous pharmaceutical approach, Gnosis carries out a seamless flow of operations, from product concept to research and development, preclinical and clinical studies, regulatory filing and Intellectual properties, manufacturing and distribution standing alongside customers.
Then follow up persistently, counsels Kate Stuart, founder and director of preclinical development at Symic Biomedical, a startup in the San Francisco Bay Area.
Frost and Sullivan's survey showed that in 2002, the top 20 pharmaceutical companies spent about a third of their R&D budgets on preclinical development.
«Collaborations with academia with renown expertise in antibiotics like the UIC team help us for this preclinical development,» said Philippe Villain - Guillot, co-founder and chief executive officer of Nosopharm.
«Improving the design, conduct, and reporting of preclinical research is of the utmost priority if we are to move ahead, with all due haste, in the development of novel treatments across a range of diseases.»
Priscilla N. Kelly Associate Editor Education: B.Sc., University of Western Australia; Ph.D., University of Melbourne Areas of responsibility: Preclinical development, translational medicine, cancer immunotherapy, drug discovery, clinical trials, gene and cell therapy E-Mail: [email protected]
Glenn Pierce, vice president of preclinical development and U.S. medical affairs at Bayer Healthcare, says, «We developed a recombinant DNA construct for this protein, and that revolutionized therapy.»
Many of his former students that entered the business as researchers have since moved on to managerial or peripheral roles, such as technology transfer, venture capital, regulatory affairs, and preclinical and clinical development.
His research efforts are divided between preclinical models, the development, performance, and monitoring of cancer immunotherapy trials and the training of the next generation of translational investigators.
Preclinical studies suggest that Cdk5 is a gene that is important for the normal wiring of the brain during early development and may be involved in some neurodegenerative disorders, including ALS, Parkinson's and Alzheimer's disease.
«The pace of preclinical and early clinical development for Zika vaccines is unprecedented,» said Barouch, corresponding author and director of the Center for Virology and Vaccine Research at BIDMC.
Overall, this work illustrates that better understanding the basic biology of the immune system in preclinical models may open up a window for the development of novel treatments for human autoimmune disease.
The third kind of marker Perera calls «preclinical,» meaning that a medical development may be in the offing.
It is currently in the preclinical stages of development.
A division of preclinical innovation will house a $ 44 million set of mostly intramural programs, including small - molecule screening and drug development for rare diseases.
Preclinical studies in mice and human cells suggested that the removal of SnCs significantly reduced the development of post-traumatic OA and related pain and created a prochondrogenic environment for new cartilage to grow and repair joints.
Our finding of similarity in clinical progression between human patients and Huntington's disease monkeys suggests monkeys could become a preclinical, large animal model for the development of new treatments.»
GLP regulations and guidelines for the conduct of preclinical testing ensure the quality and integrity of data submitted in support to the development of new treatments, foster mutual acceptance of data in the international community, serves to minimise redundant testing, minimize animal use and maximise protection of human health.
The George lab is currently performing preclinical studies for the future development of novel therapeutic approaches including Deep Brain Stimulation, Optogenetics, Chemogenetics and Precision medicine.
Our scientists engage with you in the design and execution of your preclinical drug development program using our AAALAC approved animal facilities, proprietary animal models, and extensive capabilities.
Seres Therapeutics (MCRB) Presents New Preclinical Data Supporting the Development of Microbiome Therapeutics for Immuno - Oncology at AACR
PsychoGenics has pioneered the translation of rodent behavioral responses into robust, high throughput, high content phenotyping and its drug discovery platforms, SmartCube ®, NeuroCube ®, and PhenoCube ® have led to shared risk partnerships with major pharma companies such as Sunovion and Roche and resulted in the discovery of several novel compounds now in clinical trials or advanced preclinical development.
EATRIS involvement in TRANSVAC2 will include primarily the development of a regulatory platform for preclinical, marketing authorisation and pharmacovigilance for clinical trials.
Seres Therapeutics, Inc. (NASDAQ: MCRB) today announced that new preclinical data supporting the development of microbiome therapeutics for immuno - oncology (leveraging gut microbiota to impact tumor immunotherapy) 1 will be presented today by Sceneay et al in the late breaking poster session at the 2018 American Association for Cancer Research Annual Meeting (AACR) in Chicago.
Nanotheraputics for Antibiotic Resistent Emerging Bacterial pathogens (NAREB) European Research Infrastructures for Poverty Related Diseases (EURIPED) Biomarkers for enhanced vaccines immunosafety (BioVacSafe) European network of vaccine research and development TRANSVAC Advancing novel and promising TB vaccine candidates from discovery to preclinical and early clinical development (TBVAC2020)
She is CEO of PsychoGenics Inc., a profitable preclinical CNS service company, CEO of PGI Drug Discovery LLC, a company engaged in psychiatric drug discovery with three partnered Phase II clinical programs and Adjunct Associate Professor of Neuroscience at Mount Sinai School of Medicine, Dr. Leahy has more than 25 years of experience in drug discovery, clinical develop and business development for pharmaceutical and biotechnology companies, including extensive knowledge of technology assessment, licensing, mergers and acquisitions, and strategic planning.
Non-small cell lung cancer nanoparticles pass the next stage of development in preclinical tests.
These risks and uncertainties include, among others, those relating to our ability to obtain financing and to form collaborative relationships, uncertainty regarding potential future deterioration in the market for auction rate securities which could result in additional permanent impairment charges, our ability to develop and market diagnostic products, the level of third party reimbursement for our products, risks related to preclinical and clinical development of pharmaceutical products, including the identification of compounds and the completion of clinical trials, the effect of government regulation and the regulatory approval processes, market acceptance, our ability to obtain and protect intellectual property rights for our products, dependence on collaborative relationships, the effect of competitive products, industry trends and other risks identified in deCODE's filings with the Securities and Exchange Commission, including, without limitation, the risk factors identified in our most recent Annual Report on Form 10 - K and any updates to those risk factors filed from time to time in our Quarterly Reports on Form 10 - Q or Current Reports on Form 8 - K.
Over the course of its development, PNP has secured grants from the National Institutes of Health of approximately $ 10 million to support preclinical research at Southern Research Institute and UAB.
Proclara Biosciences Presents New Preclinical Data Supporting Development of GAIM - Based Therapies at Society for Neuroscience Annual Meeting November 14, 2017
Proclara Biosciences Presents New Preclinical Data Supporting the Development of NPT189 at Alzheimer's Association International Conference (AAIC) 2017 July 18, 2017
Proclara Biosciences Presents Preclinical Data Supporting the Development of GAIM - Based Therapies for Peripheral Amyloidoses at the 16th International Symposium on Amyloidosis March 28, 2018
Dr. Bolen will oversee all aspects of R&D at Moderna, including discovery research, preclinical and clinical development, and clinical operations.
Having a strong R&D department with great experience and expertise in drug development, animal model and assay development and preclinical efficacy evaluation, the contribution of Biomedcode has been greatly valued by our partners, as documented by our participation in several collaborative research projects.
Our group is specifically working on improvement of islet isolation and transplantation protocols in clinical practice and the development of novel therapeutic options in the field of beta cell replacement with a clear translational «bench to bedside» approach by linking experimental research with preclinical and clinical work:
In favorable cases, this will result in short - circuiting of the preclinical phase of the drug development [3, 4].
Development of advanced preclinical models are needed to further elucidate the complex mechanisms underlying asthma exacerbation and investigate new therapeutic strategies.
Proclara Biosciences Presents Preclinical Data Supporting the Development of GAIM - Based Therapies for Peripheral Amyloidoses at the 16th International Symposium on Amyloidosis
In order to efficiently evaluate the newly designed vaccine candidates before testing them in clinical trials there is a need for development of reliable preclinical models.
This model offers unique capabilities for preclinical assessment of thrombosis risk in a patient - specific manner, including efficacy testing of anti-thrombotic agents, elucidation of mechanism of action, and, potentially, biomarker identification, all providing a much - needed platform for drug discovery and development.
In collaboration with the University of Massachusetts Medical School (UMMS) and Auburn University (AU), Lysogene is developing IND - supporting preclinical studies using AAV gene therapy technology to translate the initial proof of concept into a viable drug development program to the benefit of patients in urgent need.
«The initiation of the NPT088 Phase 1b trial is supported by a substantial preclinical development program and the recent successful completion of a Phase 1a study in healthy volunteers.
Scientists and vaccine developers involved in EVI projects presented project progress and research findings, highlighting one of the most important areas of EVI's activities; translation of research on diseases of poverty vaccines, focusing on early stages from preclinical to clinical development through harmonisation.