Sentences with phrase «preclinical efficacy evaluation»
One of the limitations of preclinical efficacy evaluation is the lack of appropriate animal models covering important aspects of the human disease.
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Collagen Antibody Induced Arthritis (CAIA) is a simple mouse model of rheumatoid arthritis that can be used for the fast preclinical efficacy evaluation of candidate therapeutic agents targeting pathogenic mechanisms and inflammatory processes of arthritis.
Having a strong R&D department with great experience and expertise in drug development, animal model and assay development and preclinical efficacy evaluation, the contribution of Biomedcode has been greatly valued by our partners, as documented by our participation in several collaborative research projects.
The generation, characterization and use of transgenic mice for the preclinical efficacy evaluation of therapeutics constitute one of the main R&D activities of Biomedcode.
Other humanized mice have no spontaneous phenotype and can be combined with either genetic spontaneous or inducible models of chronic inflammatory diseases yielding preclinical efficacy evaluation platforms for Rheumatoid Arthritis, Intestinal Inflammation, Psoriasis and Multiple Sclerosis.
Not exact matches
Today our rich collection of arthritis mouse models is widely used for the preclinical evaluation of the efficacy of anti-arthritic pharmaceuticals and offer an ideal platform for establishing proof of concept for novel technological advances.