Sentences with phrase «preclinical evaluation of»
The main focus of my research program is on design and preclinical evaluation of novel therapeutic strategies for treatment of metastatic cancers, including breast cancer and melanoma.
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On the other hand, humanization of drugable targets offers a valuable tool for the preclinical evaluation of human therapeutics and especially of biologics.
Today our rich collection of arthritis mouse models is widely used for the preclinical evaluation of the efficacy of anti-arthritic pharmaceuticals and offer an ideal platform for establishing proof of concept for novel technological advances.
Preclinical evaluation of a nanoformulated antihelminthic, niclosamide, in ovarian cancer.
Preclinical evaluation of adult stem cell engraftment and toxicity in the CNS of rhesus macaques.
This task will also provide a standard measurement and provide reference data and material for the preclinical evaluation of new vaccines.
W. Bogers: PhD in immunology and 20 years of experience with NHP models for the preclinical evaluation of HIV vaccine candidates as well as testing antivirals.
Nakano, a professor of neurosurgery and academic neurosurgeon at the University of Alabama at Birmingham, and Vito Coviello and Concettina La Motta, University of Pisa, Italy, are doing further preclinical evaluation of the GA11 and its analogs.
Not exact matches
Because of a lack of standardised and harmonised preclinical studies, there is limited information we can so far obtain from literature on the relative predictive value of different animal models and alternative methods for vaccine evaluation.
Other humanized mice have no spontaneous phenotype and can be combined with either genetic spontaneous or inducible models of chronic inflammatory diseases yielding preclinical efficacy evaluation platforms for Rheumatoid Arthritis, Intestinal Inflammation, Psoriasis and Multiple Sclerosis.
The generation, characterization and use of transgenic mice for the preclinical efficacy evaluation of therapeutics constitute one of the main R&D activities of Biomedcode.
Having a strong R&D department with great experience and expertise in drug development, animal model and assay development and preclinical efficacy evaluation, the contribution of Biomedcode has been greatly valued by our partners, as documented by our participation in several collaborative research projects.
Dual targeting of the epidermal growth factor receptor using the combination of cetuximab and erlotinib: preclinical evaluation and results of the phase II DUX study in chemotherapy - refractory, advanced colorectal cancer.
Collagen Antibody Induced Arthritis (CAIA) is a simple mouse model of rheumatoid arthritis that can be used for the fast preclinical efficacy evaluation of candidate therapeutic agents targeting pathogenic mechanisms and inflammatory processes of arthritis.
Biomedcode is a Contract Research Organisation (CRO) providing full preclinical drug evaluation services to the pharmaceutical industry using a unique collection of mouse models of human inflammatory diseases.
One of the limitations of preclinical efficacy evaluation is the lack of appropriate animal models covering important aspects of the human disease.