Sentences with phrase «preclinical evidence»

Research from the University of Minnesota found «strong preclinical evidence for silymarin's hepatoprotective and anticarcinogenic effects.»

Osimertinib showed preclinical evidence of concentrations in mouse brain tissue 5 - to 25-fold higher than in plasma, [16] and has shown greater penetration of the BBB in mouse models than gefitinib, rociletinib, or afatinib.

«Preclinical evidence suggests that dietary interventions, such as calorie restriction, intermittent fasting, low - fat diet and the ketogenic diet, have the potential to reverse some of these obesity - associated alterations; however, more clinical data are needed to confirm translation to human subjects.»

Medicinal cannabis use is booming for many disorders, the authors of the paper said, even without enough preclinical evidence or sufficient insights into its mechanism of action.

Their findings confirm preclinical evidence that the agent, which is derived from salmonella flagellin, is worthy of further investigation as treatment for some of the most common and most resilient solid - tumor cancers.

«Preclinical evidence strongly suggests that our product can sensitize cancers to the activity of checkpoint inhibitors and provide enhanced benefits to a larger segment of lung cancer patients compared to either therapy alone.»

The findings by the Harvard and UCB researchers provide compelling preclinical evidence that mAb CA33 treatment improves multiple disease phenotypes in two independent mouse models of obesity and T2D.

The study provides compelling, preclinical evidence for using this approach to treat acute HIV infection.

AZD3759, an EGFR inhibitor with blood brain barrier (BBB) penetration for the treatment of non-small cell lung cancer (NSCLC) with brain metastasis (BM): preclinical evidence and clinical cases.

Preclinical evidences for a beneficial impact of valproate in response of small cell lung cancer to chemotherapy.