Sentences with phrase «preclinical findings»

The Wake Forest Institute of Regenerative Medicine (WFIRM) has a unique infrastructure that provides facilities and expertise for translational studies, from basic preclinical findings all the way through Phase 2 clinical trials.

The study chronicles the use of Vasalgel ™ in groups of rhesus macaques — confirming previous preclinical findings in rabbits on the efficacy of the new device and offering a new tool to colony managers.

Preclinical findings revealed that Myb gives immune cells called regulatory T (Treg) cells the «authority» to control the strength of the immune response depending on the level of «threat», from minor infections to aggressive diseases.

The results corroborated preclinical findings and suggest that entolimod should be further studied as an immunotherapeutic anticancer agent.

«While care must be taken in extrapolating preclinical findings to the care of particular patients, we believe that these and other data do support a more comprehensive and perhaps holistic approach to caring for patients with diabetes and / or obesity,» he adds.

The researchers are reporting preclinical findings for a potential two - treatment strategy to block multiple mechanisms of cancer cell metabolism in pancreatic cancer at the American Association for Cancer Research Annual...

He further notes that there is ``... significant discordance between preclinical findings and clinical results» and ``... inefficient partnerships between academia and industry,» two challenges that must be addressed if academic research is to yield maximum clinical benefit and attain the ultimate goal of saving patients» lives.

These preclinical findings, published online ahead of print in the International Journal of Oncology, provide evidence for a potential therapeutic approach that will restore sensitivity to chemotherapy and improve treatment of inflammatory breast cancer tumors.

A major next step in the research will be to apply these preclinical findings to patients, by analyzing their tumor cells.

The preclinical findings offer encouraging potential for being translated into the clinic, said Hancock, who added that pharmaceutical companies have expressed interest in researching this approach as a possible cancer therapy.

«We're highly encouraged by these preclinical findings demonstrating the ability of our mRNA vaccine to provide robust prevention of maternal transmission of Zika and protection against congenital defects,» said Giuseppe Ciaramella, Ph.D., Chief Scientific Officer of Moderna's infectious disease - focused venture, Valera, and an author on the paper.

Based on these preclinical findings, CRI provided funding for a phase I clinical trial to test the vaccine in patients with metastatic renal cell carcinoma.