Sentences with phrase «preclinical research with»

Under the terms of the partnership, Moderna will sponsor research grants for scientists at both institutions to conduct preclinical research with novel mRNA Therapeutics ™.

Not exact matches

Looking at sixty - seven recent drug discovery projects based on preclinical cancer biology research, they found that in more than 75 percent of cases the published data did not match up with their in - house attempts to replicate.

In preclinical studies using cell models that mimicked liver cells of patients with the rare disease Friedreich's ataxia (FA), a widely used cholesterol - lowering drug increased a precursor of HDL (high - density lipoprotein), the «good cholesterol,» according to new research published in PLOS ONE from the Perelman School of Medicine at the University of Pennsylvania.

Physicists and mechanical and chemical engineers tend to start in research, and biologists with nanotechnology experience often start on the preclinical side, he adds.

«Improving the design, conduct, and reporting of preclinical research is of the utmost priority if we are to move ahead, with all due haste, in the development of novel treatments across a range of diseases.»

But in preclinical research — work with animals and cells — the preference for males has remained steadfast.

The research into quantum dots containing single magnetic ions was funded with grants from the Polish National Science Centre and the Polish National Centre for Research and Development, as well as project funds from the Centre for Preclinical Research and Tecresearch into quantum dots containing single magnetic ions was funded with grants from the Polish National Science Centre and the Polish National Centre for Research and Development, as well as project funds from the Centre for Preclinical Research and TecResearch and Development, as well as project funds from the Centre for Preclinical Research and TecResearch and Technology.

Dr. Michael Kilgard, associate director of the Texas Biomedical Device Center (TxBDC) and Margaret Forde Jonsson Professor of Neuroscience in the School of Behavioral and Brain Sciences, led the research team with Dr. Seth Hays, the TxBDC director of preclinical research and assistant professor of bioengineering in the Erik Jonsson School of Engineering and Computer Science, and postdoctoral researcher Eric Meyers PhD» 17.

Translational research, which applies findings to a health care setting, accounted for 33.3 per cent of this spend, compared with 1997 - 2010 when funding was almost entirely preclinical.

The current study is built on more than 20 years of preclinical research on memory codes led by Sam Deadwyler, Ph.D., professor of physiology and pharmacology at Wake Forest Baptist, along with Hampson, Berger and Song.

According to the authors of the study, in future researches it will be necessary to know about the action mechanism of the new products - highly selective and with low cell toxicity on in vitro tests - and broaden preclinical studies with laboratory animal models.

Through these endeavors and my current research program, I am actively engaged in fostering collaborations with academic, non-profit and industry partners to conduct large - scale rodent behavioral evaluations and preclinical studies.

Wake Forest Innovations gives you access to leading clinical and preclinical experts who partner with industry to advance medical technologies and research.

PHILADELPHIA --(July 11, 2017)-- Researchers at The Wistar Institute, an international leader in biomedical research in the fields of cancer, immunology and infectious diseases, with collaborators at Indiana University Melvin and Bren Simon Cancer Center and Syndax Pharmaceuticals, Inc., (Nasdaq: SNDX) announce the results of a preclinical study demonstrating that entinostat, Syndax's oral, Class - I histone deacetylase inhibitor, enhances the antitumor effect of PD - 1 (programmed death receptor - 1) blockade through the inhibition of myeloid derived suppressor cells (MDSCs).

IDMIT is an infrastructure for preclinical research in infectious diseases and immunology which is certified ISO9001 and which includes 1) A large animal facility with capacity to host NHP in BSL2 and BSL3 containment, 2) State - of - the - art laboratories for cell biology, immunology, molecular biology, flow cytometry and mass cytometry (CyTof), cell - sorting and confocal microscopy in BSL3 containment; 3) A biological resources centre with high storage capacity; 4) Highly innovative technologies for in vivo imaging of large animals in BSL2 and BSL3 containment, including a two - photon microscope, a PET - CT facility, and several optic based technologies (fibered endo - microscopy, near infra - red imaging).

Members of the Philadelphia Research Consortium have made a pledge to the startup and biotech community to use a universal, sponsored research agreement with all potential partners interested in exploring preclinical discovery research with participating institutions in order to facilitate meaningful collaboResearch Consortium have made a pledge to the startup and biotech community to use a universal, sponsored research agreement with all potential partners interested in exploring preclinical discovery research with participating institutions in order to facilitate meaningful collaboresearch agreement with all potential partners interested in exploring preclinical discovery research with participating institutions in order to facilitate meaningful collaboresearch with participating institutions in order to facilitate meaningful collaborations.

Janssen GPH will also prioritise work with the International Partnership for Microbicides developing the investigational drug dapivirine for use as a monthly vaginal microbicidal ring designed to prevent sexual transmission of HIV and continue its pact with Drugs for Neglected Diseases initiative for the preclinical research of a reformulated form of flubendazole for lymphatic filariasis (elephantiasis) and onchocerciasis (river blindness), Janssen GPH is also developing a new, chewable formulation of Vermox (mebendazole) that will facilitate treatment of intestinal worms in younger children.

37 experts, whose European speakers involved in INFRAFRONTIER Mouse clinics, will share with you all the new approaches that will profoundly change the basic, preclinical and biopharmaceuticals researches.

Unprecedented scale, with the capacity to produce up to 1,000 unique mRNA constructs per month, for research, drug discovery and preclinical testing — with a cycle time of a handful of weeks;

«The program will also form an excellent national meeting place for preclinical and clinical researchers in the WCMM and SciLifeLab programs with the ultimate goal of realizing Swedish translational research from molecule to man.»

Having a strong R&D department with great experience and expertise in drug development, animal model and assay development and preclinical efficacy evaluation, the contribution of Biomedcode has been greatly valued by our partners, as documented by our participation in several collaborative research projects.

Our group is specifically working on improvement of islet isolation and transplantation protocols in clinical practice and the development of novel therapeutic options in the field of beta cell replacement with a clear translational «bench to bedside» approach by linking experimental research with preclinical and clinical work:

Together, this translational program is developed within the National Cancer and Cognition Platform (CNO / Ligue Nationale contre le cancer), with the aim to collaborate in a structured way with French oncology groups, research teams as well as pharmaceutical industry, by providing preclinical models and guidance on standard operating procedures for ancillary or future studies in identified population at risk.

Together with the research and clinical resources of the nation's leading cancer hospital, we have the ability to take a program from a research hypothesis all the way to a clinical candidate supported by robust preclinical data, and into early phase clinical studies in well - defined patient populations.

Earlier research by the Wash U team found that people with preclinical Alzheimer's spent a higher percentage of their time in bed unable to fall asleep.

In an effort to further exploit the potential of Pexa - Vec to activate the immune system to fight cancer, as seen in McDonald's preclinical data, SillaJen recently announced a new clinical trial in collaboration with New York - based Regeneron Inc. to test Pexa - Vec and REGN2810, a PD - 1 checkpoint inhibitor, in combination against renal cell carcinoma, and recently signed a sponsored research agreement with UCSF to enable joint support of parallel preclinical experiments by McDonald's team.

PHILADELPHIA — In preclinical studies using cell models that mimicked liver cells of patients with the rare disease Friedreich's ataxia (FA), a widely used cholesterol - lowering drug increased a precursor of HDL (high - density lipoprotein), the «good cholesterol,» according to new research published in PLOS One from the Perelman School of Medicine at the University of Pennsylvania.

BIRMINGHAM, Alabama — December 9, 2014 — Southern Research is broadening its preclinical service offerings in drug development with the addition of Good Laboratory Practices (GLP)- compliant in vitro safety pharmacology -LSB-...]

Moussa conducted the preclinical research that led to the discovery of nilotinib for the treatment of neuro - degenerative diseases, then partnered with Pagan for the clinical study.

Thus, to support and enhance our collaborations with industry partners dedicated to improving the lives of children with nervous system disorders, the Translational Neuroscience Center (TNC) at Boston Children's Hospital has recruited Robin Kleiman, PhD, as the head of preclinical research.

The Walter Reed Army Institute of Research (WRAIR), in collaboration with the Beth Israel Deaconess Medical Center (BIDMC), has completed a second round of preclinical studies on a promising Zika... Read More

Out of all the research participants, 139 showed no sign of amyloid proteins associated with preclinical Alzheimer's.

Helmsley's investment of over $ 2.7 million supports the following preclinical, clinical, or human sample - based research projects, with the first beginning in November 2017:

New UC developments will contribute to the three categories of research CIRM hopes to establish: basic stem cell research and discovery, preclinical and clinical research, and preclinical development; centers of excellence which will work with any duel combination of stem cell discovery, clinical research and preclinical development; and special programs which will work with specialized research programs.

The Delaney Collaboratory to Cure HIV - 1 Infection by Combination Immunotherapy (BEAT - HIV Collaboratory) is a consortium of more than 30 top HIV researchers from leading academic research institutions working with government, nonprofit organizations, and industry partners to test combinations of several novel immunotherapies under new preclinical research and clinical trials.

His research group actively collaborates with several pharmaceutical companies to provide valuable preclinical data in animal models for their targeted drugs.

Learn how Preclinical Translation Services becomes part of your translational research team by providing preclinical research expertise and services for faculty engaging with industry and other fundinPreclinical Translation Services becomes part of your translational research team by providing preclinical research expertise and services for faculty engaging with industry and other fundinpreclinical research expertise and services for faculty engaging with industry and other funding agencies.

Last 10 years have been devoted to monitoring, managing, and building relationships with preclinical Contract Research Organizations (CROs) through demonstrated ability to plan, coordinate and interact professionally with all levels of staff both internally and externally.

Biomedical research scientist with significant basic and translational research experience in the field of oxidative stress and inflammation driven diseases and preclinical toxicity of drug molecules