Sentences with phrase «preclinical safety»

Gary Gintant, PhD, Abbvie, is optimistic that further advancements in the use of hiPSC - cardiomyocytes will significantly reduce the need for cardiovascular safety testing in animals, but there remains much to be learned about hiPSC - cardiomyocytes to understand the proper conditions for their use in preclinical safety testing.
The in vivo - like pathophysiology observed in this system suggests that it might serve as a useful tool for evaluating human - relevant renal toxicity in preclinical safety studies.
Performs genome - wide profiling of vector integration sites as readout of cell growth at clonal level, in basic research studies and technology development, in preclinical safety studies and in gene therapy treated patients.
«To better understand safety issues, we are making efforts to employ more modern investigational, molecular approaches to safety assessment — and increase our safety testing work force by about 10 percent,» says Phil Bentley, vice president and global head of preclinical safety at Novartis Institutes for BioMedical Research in New York City.
All this information is necessary before preclinical safety testing and product development for an AMD therapy in humans can take place.
GLP - preclinical safety studies for GSK2696273 (MLV vector - based ex vivo gene therapy for Adenosine Deaminase Deficiency Severe Combined Immunodeficiency) in NSG mice.
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), helped identify the viral strain used in the ZPIV vaccine, supported the preclinical safety testing, and is sponsoring the conduct of this trial.
Preclinical Safety of Human Embryonic Stem Cell - Derived Oligodendrocyte Progenitors Supporting Clinical Trials In Spinal Cord Injury.
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