Sentences with phrase «preclinical studies so»

Although the biotech has only conducted preclinical studies so far, there are several potential advantages to nonviral therapies, including being quicker to develop and possibly eliminating the need for a lengthy monitoring period of patients after treatment.

Not exact matches

In preclinical studies, hypothermia and anti-oxidant treatment with N - acetylcysteine (NAC) are neuroprotective following neonatal hypoxic ischemia in females, but less so in males.

«The novelty of this study is two-fold: We used a preclinical prevention paradigm of a CRF - antagonist (a drug that blocks the CRF receptor in brain cells) called R121919 in a well - established AD model — and we did so in a way that draws upon our experience in human trials.

Preclinical animal models are available that will facilitate the study of these important interactions to advance our knowledge, so that the obesity - and diabetes - driven burden of PDAC can be curbed,» commented Dr. Eibl.

Because of a lack of standardised and harmonised preclinical studies, there is limited information we can so far obtain from literature on the relative predictive value of different animal models and alternative methods for vaccine evaluation.

Preclinical studies of the effects on this drug on neurodegeneration have been done but do not appear to have been published so I do not know which disease models were used.

So far, JQ1 has been relatively well tolerated in both preclinical studies and in early phase clinical trials for cancer patients.

In preclinical in vitro studies DG041 has been shown to inhibit human platelet aggregation induced by PGE2, and to do so in a dose - dependent manner.