A preclinical study led by researchers in the United States has found that a new oral drug shows early promise for the treatment of muscular dystrophy.
Not exact matches
An editorial in the same issue of the journal notes that drug - based treatments for liver cancer are limited and that the UT Southwestern
study showed «truly remarkable results that should prompt further research under
preclinical settings, given its potential to
lead to a paradigm shift in treatment.»
The
preclinical study was
led by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James).
Rice graduate student Lifeng Yang,
lead author of the
study, designed a
preclinical experiment to test the feasibility of a multidrug approach.
The current
study is built on more than 20 years of
preclinical research on memory codes
led by Sam Deadwyler, Ph.D., professor of physiology and pharmacology at Wake Forest Baptist, along with Hampson, Berger and Song.
A Houston Methodist team
led by Mauro Ferrari, PhD and Jenny Chang, MD has received funding from the U.S. Department of Defense to complete
preclinical efficacy
studies and a future clinical trial testing a breast cancer precision drug.
The findings discovered in animal models are translated into
preclinical mechanism - driven prevention
studies that will ultimately inform epidemiologic
studies and
lead to clinical trials in humans.
Together with the research and clinical resources of the nation's
leading cancer hospital, we have the ability to take a program from a research hypothesis all the way to a clinical candidate supported by robust
preclinical data, and into early phase clinical
studies in well - defined patient populations.
After completing a series of
preclinical studies, Dr. Druker spearheaded the highly successful clinical trials of imatinib for CML, which
led to FDA approval of the drug in record time.
MSCs have been extensively tested in
preclinical and clinical
studies, and have
led to promising results in treatment of numerous diseases.
Moussa conducted the
preclinical research that
led to the discovery of nilotinib for the treatment of neuro - degenerative diseases, then partnered with Pagan for the clinical
study.
BIRMINGHAM, Ala. — April 7, 2016 — Paul Bushdid, Ph.D., has joined Southern Research to
lead its Developmental & Reproductive Toxicology (DART) program, which performs complex
preclinical studies to ensure -LSB-...]
These
preclinical studies have
led to a clinical trial for patients with glioblastoma multiforme (www.clinicaltrials.gov NCT02046187).
These encouraging results
led us to believe that pimobendan could be effective in
preclinical mitral valve disease and that the investigation of this through the EPIC
Study was useful and worthwhile.