Sentences with phrase «preclinical therapeutic development»

Not exact matches

The George lab is currently performing preclinical studies for the future development of novel therapeutic approaches including Deep Brain Stimulation, Optogenetics, Chemogenetics and Precision medicine.

These forward - looking statements are based on management's current assumptions and expectations and involve risks, uncertainties and other important factors, specifically including those relating to Lexicon's ability to successfully conduct preclinical development of its drug candidates and advance such candidates into clinical development, achieve its operational objectives, obtain patent protection for its discoveries and establish strategic alliances, as well as those relating to manufacturing, the regulatory process, intellectual property rights, and the therapeutic or commercial value of its drug candidates, that may cause Lexicon's actual results to be materially different from any future results expressed or implied by such forward - looking statements.

Our group is specifically working on improvement of islet isolation and transplantation protocols in clinical practice and the development of novel therapeutic options in the field of beta cell replacement with a clear translational «bench to bedside» approach by linking experimental research with preclinical and clinical work:

Development of advanced preclinical models are needed to further elucidate the complex mechanisms underlying asthma exacerbation and investigate new therapeutic strategies.

Such models will allow for further understanding of critical genes and microRNAs involved in sarcoma development, progression and metastasis and can be utilized as preclinical models for therapeutic testing and efficacy.

Such models will allow for further understanding of critical genes and microRNAs involved in sarcoma development, progression and metastasis and utilized as preclinical models for therapeutic testing and efficacy.

Catherine Priest, PhD, VP of Preclinical Development at Neurona, filed the first successful IND application for a human pluripotent stem cell - based therapeutic as a former Senior Director at Geron Corporation.

Although both forms are highly active, ADCs with alkylating IGNs demonstrated a better safety profile, and high therapeutic indices in vivo.23, 24 Here we describe the development and preclinical characterization of a novel CD123 - targeting ADC, IMGN632, consisting of a humanized anti-CD123 antibody conjugated to an alkylating IGN payload via a protease cleavable linker.

The company's preclinical and discovery programs are focused on the development of new treatments for multiple therapeutic areas, including neuromuscular disease, oncology and infectious disease.