A gene linked to bowel cancer recurrence and shortened survival could help
predict outcomes for patients with the gene - and take scientists a step closer to development of personalized treatments, reveals research in the journal Gut.
Without the benefit of a biopsy, it can ultimately be difficult to
predict the outcome for patients treated with radiation alone.
Not exact matches
«Moving forward, we'll need to conduct additional studies of many more
patients to show that getting functional scans in the first hours or days after a stroke could provide valuable information
for predicting outcome and tracking recovery.»
«We wanted to develop a novel strategy with PET imaging
for non-invasively determining EGFR mutation status in real - time,
predict NSCLC
patients who may benefit from EGFR - TKI therapy, and monitor EGFR - TKI treatment
outcome.»
«Detecting genetic associations in cases of acute viral bronchiolitis is the first step toward the development of tests to
predict the possible clinical
outcome for each
patient diagnosed with the disease soon after arrival at the emergency room,» said Fernando Augusto de Lima Marson, a researcher at FCM - UNICAMP and one of the authors of the article.
«While these observational data can not prove that treating
patients based on the results of CTA testing will automatically result in better health
outcomes, they do provide new information enabling a more informed choice of testing
for patients with stable chest pain, especially
for predicting future cardiovascular risk.»
Better treatments
for heart failure and new ways of
predicting patient outcomes are needed, researchers concluded.
Analyzing a
patient's cancer
for genetic mutations is the basis
for predicting treatment
outcomes using various cancer drugs and protocols.
Using a rapid learning approach, the goal of M2Gen is to accelerate the science of precision medicine by creating evidence and knowledge - based solutions that identify a
patient's susceptibility to disease,
predict how the
patient will respond to a particular drug, and match
patients to the best therapies
for an optimal treatment
outcome.
I think we all agree that we over treat prostate cancer in this country compared to what you see in Europe with similar
outcomes and so but I think this is where the human or the Cancer Genome Project or at least better biomarkers
for looking at mutations that we already know occur in these diseases I think hopefully within the next few years every single
patient who is diagnosed with prostate cancer those biopsies will be characterized and then the
patients followed, hopefully watchful waiting and we'll ultimately get a correlation between what mutational events
predict a rather dormant disease as opposed to a very aggressive disease.
Genetic testing could be used to
predict clopidogrel efficacy in individual cats with heart disease and facilitate personalized medicine decisions to help improve
outcomes for these
patients.
An important validation criterion
for a diagnosis is its ability to
predict outcome and to identify
patients in need of treatment [40].
There are well - documented associations between posttraumatic stress disorder (PTSD) and intimate relationship problems, including relationship distress and aggression, 1 and studies demonstrate that the presence of PTSD symptoms in one partner is associated with caregiver burden and psychological distress in the other partner.2 Although currently available individual psychotherapies
for PTSD produce overall improvements in psychosocial functioning, these improvements are not specifically found in intimate relationship functioning.3 Moreover, it has been shown that even when
patients receive state - of - the - art individual psychotherapy
for the disorder, negative interpersonal relations
predict worse treatment
outcomes.4, 5
In support of these results, multilevel modeling of the
outcomes revealed the
predicted time × condition interaction
for the primary
outcome of clinician - rated PTSD symptom severity (t37.5 = − 3.09; P =.004) and
for patient - reported relationship satisfaction (t68.5 = 2.00; P =.049).
A study of individual cognitive therapy
for bipolar disorder showed positive
outcomes at 1 - year follow - up, but the benefits were reduced over time, suggesting the need
for booster sessions to sustain the gains.19 As with many forms of therapy, CBT has been found to be more successful in reducing relapse in the depressive pole compared with the manic pole.30 A large randomised trial of CBT showed no difference between CBT and treatment as usual, when all participants were included in the analyses.31 However, results of a post-hoc analysis suggested that CBT was effective
for participants who reported fewer than 12 prior episodes of illness and were not acutely unwell when therapy began; numbers of episodes of mania rather than depression seemed to
predict treatment response.32 Such data can help guide the clinical application of CBT
for bipolar
patients.
For example, higher levels of depression have been shown to be predictive of poorer treatment outcomes for patients with chronic pain, 11 as well as higher health care costs over time.12 Equally, the presence of pain in people being treated for mood disturbance has predicted delayed responses to mood interventions.13 Therefore, improving our understanding of how chronic pain and depression are linked, and treating both components offers the prospect of enhancing treatment effects beyond the benefits of treating either condition alone
For example, higher levels of depression have been shown to be predictive of poorer treatment
outcomes for patients with chronic pain, 11 as well as higher health care costs over time.12 Equally, the presence of pain in people being treated for mood disturbance has predicted delayed responses to mood interventions.13 Therefore, improving our understanding of how chronic pain and depression are linked, and treating both components offers the prospect of enhancing treatment effects beyond the benefits of treating either condition alone
for patients with chronic pain, 11 as well as higher health care costs over time.12 Equally, the presence of pain in people being treated
for mood disturbance has predicted delayed responses to mood interventions.13 Therefore, improving our understanding of how chronic pain and depression are linked, and treating both components offers the prospect of enhancing treatment effects beyond the benefits of treating either condition alone
for mood disturbance has
predicted delayed responses to mood interventions.13 Therefore, improving our understanding of how chronic pain and depression are linked, and treating both components offers the prospect of enhancing treatment effects beyond the benefits of treating either condition alone.14