Sentences with phrase «predict outcomes of patients»

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Based on these ex vivo experiments (in cells isolated from patients and then exposed to PD - L1 blocking agents outside of the body), they predict that when actual patients are given PD - L1 blocking agents, their viral load at the time will influence the «net» outcome, i.e., whether the blockage boosts or weakens the overall anti-HIV immune response.

«Moving forward, we'll need to conduct additional studies of many more patients to show that getting functional scans in the first hours or days after a stroke could provide valuable information for predicting outcome and tracking recovery.»

The researchers predict that the approach described in their study will pave the way to further develop the modelling of biomedical parameters and large - scale datasets in order to improve biological knowledge and patient outcome.

Although self - appraisal of overall well - being may mediate physiologic responses to surgery, patient - reported health status has not been extensively studied among bladder cancer patients to date, and its utility in predicting postoperative outcomes, such as complications, has not been previously examined.»

We identified patients with mutations that predict phenomenal outcomes in the disease; this is a group of women with endometrial cancer who won't need the financial, physical or emotional toll of chemotherapy at all — they're patients who are probably cured by surgery alone.

Finally, all of this data can be combined to predict patient outcomes including overall survival.

«Gene profiling can help predict treatment response and could save money in RA: Future personalisation of RA treatment may improve patient outcomes.»

«New frailty test predicts risk of poor outcomes in elderly patients.»

«Detecting genetic associations in cases of acute viral bronchiolitis is the first step toward the development of tests to predict the possible clinical outcome for each patient diagnosed with the disease soon after arrival at the emergency room,» said Fernando Augusto de Lima Marson, a researcher at FCM - UNICAMP and one of the authors of the article.

In addition to offering early evidence of a drug's effectiveness, if depth of response predicts patient outcomes, then, Doebele says, depth of response may be a useful goal of treatment.

Calibration is the agreement between the predicted risk and actual outcomes on average, and across the spectrum of predicted risk — from low to high, said Mark E. Cohen, PhD, one of the study's authors and a statistical manager in the ACS Division of Research and Optimal Patient Care.

«While these observational data can not prove that treating patients based on the results of CTA testing will automatically result in better health outcomes, they do provide new information enabling a more informed choice of testing for patients with stable chest pain, especially for predicting future cardiovascular risk.»

Better treatments for heart failure and new ways of predicting patient outcomes are needed, researchers concluded.

Other alterations and the presence of particular immune targets could serve as better markers to help pathologists accurately diagnose mesothelioma and predict which patients will have poor or better outcomes.

Because chronic hyperglycemia... potentially predicts a poor therapeutic effect of aerobic exercise on glycemic control and fitness, using exercise to treat patients with poorly controlled T2DM may have limited chances of a successful outcome,» the study concludes.

«Triple - negative breast cancers tend to be more aggressive compared to other types of breast cancers, and being able to predict response to therapy could greatly impact treatment decisions and patient outcomes,» says study author Shaveta Vinayak, MD, oncologist at UH Case Medical Center and Assistant Professor at Case Western Reserve University School of Medicine.

H. Mine past patient data to predict future patient outcomes Predict response to standard treatments through retrospective analysis of patient spepredict future patient outcomes Predict response to standard treatments through retrospective analysis of patient spePredict response to standard treatments through retrospective analysis of patient specimens.

Levels of circulating tumor DNA (ctDNA) predicted worse outcomes including relapse and survival in patients with resected stage II / III melanoma, according to the results of a study published in Annals of Oncology.

Of 21 patients who responded to a particular drug or drug combination, their xenograft mice correctly predicted the outcome 90 percent of the timOf 21 patients who responded to a particular drug or drug combination, their xenograft mice correctly predicted the outcome 90 percent of the timof the time.

A gene linked to bowel cancer recurrence and shortened survival could help predict outcomes for patients with the gene - and take scientists a step closer to development of personalized treatments, reveals research in the journal Gut.

The expression of immune markers and T - cell subsets can help predict outcomes of sentinel lymph node — positive melanoma patients, according to a new study.

Using a rapid learning approach, the goal of M2Gen is to accelerate the science of precision medicine by creating evidence and knowledge - based solutions that identify a patient's susceptibility to disease, predict how the patient will respond to a particular drug, and match patients to the best therapies for an optimal treatment outcome.

Without the benefit of a biopsy, it can ultimately be difficult to predict the outcome for patients treated with radiation alone.

At Overlawyered, Ted Frank predicts that the obvious outcome of this case is that «doctors will simply overwarn, and tell all of their patients not to drive.»

Health data analytics allows systems to create holistic views of patients, personalise treatments, improve communication, and streamline services to save costs and predict better health outcomes

An important validation criterion for a diagnosis is its ability to predict outcome and to identify patients in need of treatment [40].

While there are many theoretical and practical approaches to psychotherapy, research has consistently shown that regardless of the approach, the most powerful factor in predicting the outcomes of therapy is the quality of the therapeutic relationship between the psychotherapist and the patient.

There are well - documented associations between posttraumatic stress disorder (PTSD) and intimate relationship problems, including relationship distress and aggression, 1 and studies demonstrate that the presence of PTSD symptoms in one partner is associated with caregiver burden and psychological distress in the other partner.2 Although currently available individual psychotherapies for PTSD produce overall improvements in psychosocial functioning, these improvements are not specifically found in intimate relationship functioning.3 Moreover, it has been shown that even when patients receive state - of - the - art individual psychotherapy for the disorder, negative interpersonal relations predict worse treatment outcomes.4, 5

In support of these results, multilevel modeling of the outcomes revealed the predicted time × condition interaction for the primary outcome of clinician - rated PTSD symptom severity (t37.5 = − 3.09; P =.004) and for patient - reported relationship satisfaction (t68.5 = 2.00; P =.049).

It has been found to predict treatment adherence (compliance) and outcome across a range of client / patient diagnoses and treatment settings.

A study of individual cognitive therapy for bipolar disorder showed positive outcomes at 1 - year follow - up, but the benefits were reduced over time, suggesting the need for booster sessions to sustain the gains.19 As with many forms of therapy, CBT has been found to be more successful in reducing relapse in the depressive pole compared with the manic pole.30 A large randomised trial of CBT showed no difference between CBT and treatment as usual, when all participants were included in the analyses.31 However, results of a post-hoc analysis suggested that CBT was effective for participants who reported fewer than 12 prior episodes of illness and were not acutely unwell when therapy began; numbers of episodes of mania rather than depression seemed to predict treatment response.32 Such data can help guide the clinical application of CBT for bipolar patients.

For example, higher levels of depression have been shown to be predictive of poorer treatment outcomes for patients with chronic pain, 11 as well as higher health care costs over time.12 Equally, the presence of pain in people being treated for mood disturbance has predicted delayed responses to mood interventions.13 Therefore, improving our understanding of how chronic pain and depression are linked, and treating both components offers the prospect of enhancing treatment effects beyond the benefits of treating either condition alone.14