Sentences with phrase «predicted open reading frames»

The predicted open reading frames (ORFs) for most of these transcripts are truncated, due to a premature stop codon.

Not exact matches

Open Reading Frame E3 - 10.9 K of Subspecies B1 Human Adenoviruses Encodes a Family of Late Orthologous Proteins That Vary in Their Predicted Structural Features and Subcellular Localization.

Each allele eliminated the pathogenic p.K1872X mutation and removed 59 or 22 amino acids from the predicted encoded protein, while restoring the open reading frame to encode the critical C terminal region of BRCA2 (Fig. 1C, labeled D1 and D2, Supplementary Tables S1 and S2).

All deletion alleles eliminated the pathogenic p.K1872X mutation and restored the open reading frame of BRCA2, producing predicted proteins of residue length 3,409 to 3,212 compared with the 3,418 amino acid full - length BRCA2 protein.

After assembly, the plasmids were manually quality controlled and open reading frames (ORFs) were predicted using Glimmer 3.02 [53].