In its first phase, the money was distributed between nine structural - biology research consortia, each of which would go on to produce dozens of protein structures per year — with the lofty goal of eventually
predicting structures for most of the amino - acid sequences possible in nature.
Not exact matches
Gods will is
for us humans today to evolved to a level of conciousness that will prepare us
for the challenges of our future survival, Scientists now
predicts of hardships in the future due to over population and changes to the natural environment.and that is happening now with activists through out the world are reminding us of protecting nature.That is why we need a phsychological revolution to hasten the evolution of consciousness that will address the problems.Ideological and philosophical enlightenment had the past great minds to develop ideas and belief because God sent them to reality in their times.Abraham, Jesus, Mohammad, Buddha, and many other religious leaders to teach humanity the doctrines that God willed to be appropriate and applicable in those periods of their existence, Also great philosophers in another dimension of social involvement were born to interprete and connect philosophically as the second element of our conscience, Kant, Marx and countless of them also were born.To complete the triangular
structure or dimension of our conscience is knowledge.
No biblically oriented, responsible Jewish theology can accept such a substitution of an ontological
structure for the God of Abraham, Isaac, and Jacob whose actions humanity can not
predict and whose actions are not subject to an overreaching logical necessity to which they must conform.
For a philosophy of mechanism, these building blocks are assumed to be static either in being or
structure (or at least to have static essential parts), and it is from such fixed
structure that the mechanist seeks to
predict the nature of the whole, normally by the laws of mechanics.
A further reason
for the decline in royal power, and one that was not
predicted at the time, was the shift of the United Kingdom to a formal federal
structure in the middle part of the century.
Queens Congresswoman Carolyn Maloney, who has pressed
for repairs to the seawall
for years, said in 2005 that experts found a 200 - foot portion of the
structure had «completely failed» and
predicted more deterioration in the coming years.
Her calculations informed an algorithm that
predicts,
for a given protein, what mRNA sequence would produce the
structure most appealing to a ribosome.
At the ceremony in Warsaw, Turner — who is a chemistry professor at the University of Rochester known
for the «Turner Rules»
for predicting RNA
structure — said the main goal of his and Kierzek's research has been to move as quickly as possible from «genome sequence to drugs that can help cure somebody.»
For example, molecules with sulfur groups tend to produce a «garlicky» smell, and molecules with a similar chemical
structure to vanillin, from vanilla beans,
predicts whether subjects will perceive a «bakery» smell.
Fischer's colleague, Angel Rubio, director of the Max Planck Institute
for the
Structure and Dynamics of Matter in Hamburg and a professor at the University of the Basque Country in Spain, made extensive supercomputer calculations taking this surface binding into account, but still was not able to
predict the intermediates actually observed.
An article, «Smaller amygdala and medial prefrontal cortex
predict escalating stimulant use,» published online on May 13 in Brain: A Journal of Neurology has found that individual differences in brain
structure could help to determine the risk
for future drug addiction.
In 2003, Ceder and his team first showed how a database of quantum - mechanics calculations could help to
predict the most likely crystal
structure of a metal alloy — a key step
for anyone in the business of inventing new materials.
«The ability of the top teams to
predict population - level toxicity
for unknown compounds — based on similarities in chemical
structure to known compounds — far surpassed our anticipations,» says Lara Mangravite, Director of Systems Biology at Sage Bionetworks.
«If this is so, and we can use this code to
predict protein
structure, we will gain a powerful tool
for understanding how certain mutations cause disease and how to fix them.»
In this case, Lu was able to calculate precise measurements
for the construction of a photonic crystal
predicted to produce the manifestation of Weyl points — with dimensions and precise angles between arrays of holes drilled through the material, a configuration known as a gyroid
structure.
The new work
predicts 614 protein
structures, representing 12 % of the estimated 5211 protein families
for which no experimental
structure exists.
That produced a fresh set of structural types
for analysis by the Rice team's MiChroM program, a cousin of the lab's AWSEM energy landscape algorithm that
predicts the
structures of proteins.
Berzins, Bunge and Goodyer are aiming to develop a higher resolution model of skin so that they can
predict how skin
structure affects the rate of chemical penetration through skin and give a level of confidence
for their result.
«In terms of practical nature conservation, these results signify that in the future it will no longer be sufficient to preserve small, isolated reserves — while these benefit specialized species with a simple genetic
structure, the bulk of species that depend on an exchange between local populations will lose out in the medium to long term,»
predicts Schmitt, and he adds in closing, «This will lead to a further decline of numerous insect species — with dramatic consequences
for entire food webs and ecosystems.»
It is this strange overlap makes it impossible to
predict which combinations of algorithms will work best
for an individual
structure.
The ability to
predict crystal
structures could therefore enable the design of materials with superior properties,
for example the creation of brighter pigments, more effective pharmaceuticals, or even lower calorie foodstuff.
«The holy grail of this particular problem is to say, I've written down this chemical formula
for a material, and then just from the formula be able to
predict its
structure — a goal since the dawn of chemistry,» said Garnet K. L. Chan, the A. Barton Hepburn Professor of Theoretical Chemistry at Princeton University.
Dr Marcus Neumann, author of the computer program GRACE
for crystal
structure prediction, which
predicted eight out of nine targets correctly in this blind test and eight out of ten targets in the previous two blind tests, said: «Obviously, we are delighted with these results, in particular because unlike in earlier blind tests they have been obtained by a fully automated procedure that can be used as a black box in industrial working environments.»
Researchers at Whitehead Institute have uncovered a framework
for regeneration that may explain and
predict how stem cells in adult, regenerating tissue determine where to form replacement
structures.
Twenty five research groups who have been developing methods
for predicting crystal
structures of organic molecules took part in the latest test.
(PROfile Multiple Alignment with
predicted Local
Structure) a progressive method for aligning multiple protein sequences, with enhanced profile information from database searches and secondary structure pr
Structure) a progressive method
for aligning multiple protein sequences, with enhanced profile information from database searches and secondary
structure pr
structure prediction.
To study such mechanisms, we employ the laws of physics and the rules of evolution to develop and apply computational methods
for predicting the 3D
structures of macromolecules and their complexes.
To provide the basis
for predicting and optimizing the complex interplay of materials and geometric effects in plasmon decay - induced excited carrier phenomena, we combined \ emph -LCB- ab initio -RCB- electronic
structure calculations, electromagnetic simulations and Boltzmann transport models.
Functional variation in vasopressin 1a receptor gene
structure within and between vole species
predicts behavior Elizabeth Hammock, Center
for Behavioral Neuroscience, Emory University, Atlanta, Georga, USA
«Our approaches are going to be useful
for predicting structures and even modeling de novo, which we're working on now,» she says.
HAR1 does not code
for a protein but
for a long RNA, a type of molecule that guides proteins or modulates their expression.5 We
predicted that the HAR1 RNA could fold into a three - dimensional
structure because its conserved sequence has palindromic regions that pair up to form a series of interconnected «stems» that look like ladders — think of an untwisted DNA double helix.
The evaluated models will be used
for predicting the different services soil renders to ecosystems in a dynamic way and
for testing classical theory, where soil
structure is not directly taken into account.
Although no observational evidence has yet been found
for such
structures, this remains an active area of research, in which interest has revived since it was discovered that very similar objects would be
predicted by many cosmological scenarios based on fundamental string theory.
For example, it is used to identify correlations between gene sequences and diseases, to
predict protein
structures from amino acid sequences, to aid in the design of novel drugs, and to tailor treatments to individual patients based on their DNA sequences (pharmacogenomics).
It has been my experience though - based on almost ten years of data collection and analysis and owing to the fact that ultimate muscular potential is so closely tied to bone
structure - that most healthy people can come surprisingly close to what such a formula can
predict... if they train correctly
for long enough.
If you are lifetime drug - free and have approximately average bone
structure girths
for your height, use this formula (and bulked adjustment) to set a realistic and accurate bodyweight goal
for yourself (individuals with significantly smaller or larger than average bone
structures for their heights are more accurately treated in the e-book Your Muscular Potential: How to
Predict Your Maximum Muscular Bodyweight and Measurements).
For example, reading text requires use of a very complex combination of skills: recognizing and producing sounds, linking sounds to letter, rapidly linking this all to a whole page of words, all the while
structuring what is read, asking questions about what is read, summarizing, and
predicting what is coming next in order to ultimately comprehend what was read.
The article
predicted Greece would leave the eurozone in a «
structured and orderly fashion,» and that it would «reintroduce the drachma alongside the euro
for a three - year time frame.»
To
predict how long this will take, and to choose the best drying methods
for different wall
structures, researchers at Fraunhofer IBP have conducted laboratory tests on numerous different types of masonry units.
However, most of the current Earth system models that
predict climate change and C cycle feedbacks lack both a mechanistic formulation
for height -
structured competition
for light and an explicit scaling from individual plants to the globe.
Until such time as the durability of building envelopes can be designed and
predicted as accurately as that
for structures, measures of sustainability remain highly questionable at the design stage.
Inter-specific competition was found to be similar in both the unconditioned natural and the conditioned artificial community, suggesting that
for diatom communities, short - term manipulative experiments may be used to
predict the effects of long - term environmental forcing on community
structure.
It's
predicted that the cumulative global market
for floating wind turbine
structures could exceed $ 200 billion by 2030.
Using the statistical
structure of temporal correlations in fluctuations
for generated and forecast power time series, we quantify two types of forecast error: a timescale error (eτ) that quantifies deviations between the high frequency components of the forecast and generated time series, and a scaling error (eζ) that quantifies the degree to which the models fail to
predict temporal correlations in the fluctuations
for generated power.
Looking further ahead, when alternative business
structures come into effect, which is currently
predicted for 2011, there will presumably be the need
for a major overhaul of the rules on separate businesses and recognised bodies.
Some additional distinctions between Liam Brown's «law company» and the traditional law firm include: (1) performance and reward
structures that value output over input; (2) closer alignment with the financial and enterprise objectives of the consumer; (3) a corporate
structure that takes a long - term, client - centric view over profit - per - partner; (4) continuous process improvement; (5) investment in technology; (6) focus on «the right resource
for the task»; (6) compressed delivery time; (7) a continuous quest to use technology and process to automate tasks and gather «big data»
for benchmarking,
predicting, and quantifying risk; (8) a transparent, 24/7/365 accessible connection with legal consumers; (9) supply chain management expertise; and (10) reduced cost.
Although the demise of the hourly rate has been
predicted for many years, this sort of arrangement could have a profound effect on the economics and
structure of a law firm.
Tags
for this Online Resume: Documentation, Business Analysis, Business Analyst, Management, Pain Management,
Predict,
Predict (Data Dictionary), Underwriter,
Structured Query Language, Systems Analysis
Presumed indices of the absence of internalized
structure, including Approval of Others, Physical Appearance, and Competition,
predicted lower Self - Esteem; although, the hypothesized linkage with greater Anger was non-significant
for Approval of Others.
Using instruments such as the Parenting Dimensions Inventory (PDI; Power, 2002; Slater & Power, 1987), research over several decades has found the broad dimensions of support,
structure, and behavioral control to
predict parenting practices that are important
for children's long - term development and well - being (Hughes, Power, Fisher, Mueller, & Nicklas, 2005).