Sentences with phrase «predictive gene signature»

Not exact matches

Molecular characterization of the cells that undergo cell fate transition upon oncogenic Pik3ca expression demonstrated a profound oncogene - induced reprogramming of these newly formed cells and identified gene expression signatures, characteristic of the different cell fate switches, which was predictive of the cancer cell of origin, tumour type and clinical outcomes in women with breast cancers.

We also have longstanding collaborations with GlaxoSmithKline to study inhibitors of the MAPK pathway in immune cells and melanoma, tumour antigens and predictive immune gene signatures.