The phrase
"predisposed individuals" refers to people who are more likely to have a certain condition or behavior because of their genetics or other factors.
Full definition
CONCLUSIONS: Small amounts of supplementary iodine (250 microg) cause slight but significant changes in thyroid hormone function
in predisposed individuals.
An average 10 % of all cancers are due to strong alterations in genes
which predispose individuals to multiple cancers, often at young ages, and that can be inherited and passed on to their children.
Celiac disease is an autoimmune digestive disorder in which genetically
predisposed individuals develop an immune response to gluten, a protein found in cereal grains, wheat, rye, and barley.
Research has demonstrated an association between COPD and inflammation, raising the question of whether prolonged inflammatory conditions such as rheumatoid
arthritis predispose individuals to COPD.
Following the gene discovery announced in September, deCODE scientists have discovered common versions of two additional genes that
significantly predispose individuals to obesity.
Regular caffeine consumption may increase the risk of heart attack in genetically
predisposed individuals who metabolize (break down) caffeine slowly [183,184].
Long - term «leakiness» may
also predispose an individual to autoimmune responses such as Crohn's disease (inflammatory bowel disease) and rheumatoid arthritis.
It is hypothesized that chronic ingestion of a high - carbohydrate diet promotes obesity and increases the demand on β - cells for insulin secretion,
thereby predisposing individuals to hyperinsulinemia, apoptosis, β - cell failure, and development of type 2 diabetes (21).
A neck injury can pretty much affect any part of the body and if the energy flow deficit is severe, this can
even predispose the individual to cancer.
United States About Blog Genetics uses information from one or two genes to explain a disease or condition, whereas genomics examines all of the genetic information to determine biological
markers predisposing an individual to disease.
By By Jeri Breiner, The idea of getting divorced tends to
immediately predispose individuals to become fearful of change, of backlash, and of the unknown territories ahead.
This suggests that, although low self - esteem is a vulnerability to develop depressive symptoms over time, having low self - esteem in early adolescence does not
necessarily predispose the individual to develop depressive symptoms during development into adulthood.
Although there is a genetic link to diabetes,
which predisposes individuals to Type 2 diabetes, this risk is exacerbated by poor diet and lifestyle.
Previous studies have indicated that early exposure to complex foreign proteins, such as cow's milk proteins, increases the risk of type 1 diabetes
in predisposed individuals.
This is intriguing given that inflammation during pregnancy, which alters MHCI levels in the fetal brain, may slightly increase the risk of autism in
genetically predisposed individuals, she said.
Those babies that received the additional nutrition had achieved a fat mass that was 22 % to 38 % higher than those given standard formula by the age of 5 to 8 years, a situation that is known to
predispose individuals to becoming overweight as adults.
«The results raise significant questions over the long - term effects of infertility and whether it is infertility itself or an underlying condition that
predisposes an individual to infertility that drives these increased risks,» Stentz said.
New research shows that adolescent binge drinking can lead to epigenetic reprogramming that
predisposes an individual to later psychiatric disorders such as anxiety.
«In short,» said Pandey, «epigenetic reprogramming in the brain due to early life experiences or exposure to alcohol can lead to the changes in gene functions and
predispose an individual to adult psychopathology.»
«There are also genetic mutations that
predispose individuals to develop colon cancer in early adulthood — and these individuals have been found to develop intestinal inflammation even before the appearance of their neoplastic disease,» he says.
«Among them were multiple genes known to
predispose individuals to Parkinson's — so we show that various genetic forms of Parkinson's are directly related to alpha - synuclein.
The findings provide insight into the biological pathways that may
predispose an individual to disease and could ultimately lead to the development of new therapeutic avenues to treat the five major psychiatric illnesses.
It also found several gene variants that
predispose individuals to type 1 diabetes and three new genes for Crohn's disease.
They relate their hypothesis to life - history theory, which talks of balancing the preservation of one's health and the production of offspring that will survive to reproduce themselves, and theorize that «early life stressors may
predispose an individual to adaptively suppress fertility when situations are less than optimal, leading to periods of fertility difficulties even following previous births.»
This enables them to study the mechanisms by which certain genes can
predispose an individual to a particular disease.
The researchers are now examining changes in the brains of individuals who go on to develop psychotic disorders, as well as potential environmental and genetic risk factors that may
predispose individuals to poor cognition.
Psoriasis could
predispose individuals to a more sedentary lifestyle, leading to behaviors that predispose them to obesity and diabetes, or these conditions could be a cause of psoriasis.
A second study from the Finn - Perkins lab at UIC, recently published in the American Journal of Respiratory Cell and Molecular Biology, showed that even prior to birth, exposure to specific compositions of bacteria may elicit an inflammatory immune response that could
predispose individuals to asthma.