The hypothesis then, is that inheritance of these putative low penetrance genes
predisposes white skinned peoples to melanoma but that as this predisposition is weak, there may be only one or occasionally two cases in the family.
Short - coated breeds such as English bulldogs (FIGURE 5), Staffordshire terriers, and Boston terriers, along with longer - coated breeds such as shih tzus, West Highland
White terriers, and Scottish terriers, seem to be
predisposed.2, 4 In Chinese Shar - Peis,
skin thickness may make finding the mites on a deep
skin scraping difficult, and diagnosis may require obtaining
skin biopsy samples for histopathology (see DIAGNOSIS).2, 4,5 Additional
predisposing factors are listed in BOX 1.
White cats of any breed are
predisposed to development of squamous cell carcinoma, a malignant tumor which can develop anywhere on the
skin or mucous membranes, including the eyelids.