Sentences with phrase «predisposing genetic»

It is interpreted liberally and protects more categories for individuals such as marital status, sexual orientation, military status, domestic violence, criminal conviction records, and predisposing genetic characteristics.

Additionally, it appears that certain families may have predisposing genetic factors to the disease.

Professor Widschwendter says: «The data is encouraging since it shows the potential of a blood based epigenetic test to identify breast cancer risk in women without known predisposing genetic mutations.»

But the precise risk of these conditions developing in children of older fathers has not been calculated, and other predisposing genetic and environment factors are likely to play a role.

There can be a number of reasons you may be struggling with addiction whether it is something that stemmed from your past, difficult decisions, or from a predisposed genetic condition.

Not exact matches

As an adult, he notes that his mother was sort of right: There are genetic factors that predispose some people for drug addiction.

He has an interesting take on original sin, which, from an evolutionary perspective, he suggests, can be seen as a trigger for certain genetic mechanisms predisposing us to selfishness and aggression.

If genetic inheritance and social inheritance combine to predispose us to behavior with moral significance, then we can hypothesize that some level of biological and environmental determinism has an effect on everyone's life.

While there is not technically a twin gene, there is a genetic component that makes some women predisposed to conceiving twins.

Tracey have you read or heard any information on the prospect that SIDS, true SIDS with no suffocation in blankets etc may actually be related to the infants heart suddenly stopping unexplainably I think smoking etc may affect this however it could be predisposed and genetic and maybe all our SIDS prevention is futile and it has only prevented suffocation etc?!

Our evolutionary inheritance provides us with a predisposed tabula rasa, devoid of innate ideas but endowed with a degree of fundamental hardwiring in the form of a set of instincts aimed narrowly at survival, passed on through our genetic heritage.

An unprecedented search for the roots of canine aggression and fear has identified genetic variants that predispose a dog toward such behaviors.

If the silencing occurred in a gene responsible for suppressing tumor formation, the result would appear the same as genetic mutations that predispose people to cancer.

«There are also genetic mutations that predispose individuals to develop colon cancer in early adulthood — and these individuals have been found to develop intestinal inflammation even before the appearance of their neoplastic disease,» he says.

«Among them were multiple genes known to predispose individuals to Parkinson's — so we show that various genetic forms of Parkinson's are directly related to alpha - synuclein.

Genetic tests could one day indicate if patients are predisposed to high levels of TNF — possibly associated with the newly identified receptor gene variant — helping to identify patients that will respond to antibody therapy.

Genetic risk score could be useful in identifying people who are predisposed to obesity and could ultimately lead to personalized dietary recommendations.

Genetic factors can contribute to the degree of longevity in at least two important ways: An individual may inherit certain genetic variations that predispose him or her to disease that decreases longevity; other gene variants may confer disease resistance, thereby increasGenetic factors can contribute to the degree of longevity in at least two important ways: An individual may inherit certain genetic variations that predispose him or her to disease that decreases longevity; other gene variants may confer disease resistance, thereby increasgenetic variations that predispose him or her to disease that decreases longevity; other gene variants may confer disease resistance, thereby increasing it.

These findings could include genetic variants that would predispose patients and their family to a variety of conditions including other cancers, Alzheimer's, and cardiovascular disease.

Researchers suspect that many of these genetic anomalies can predispose people to the disorder, or directly contribute to it.

In the new work, researchers looked at genetic and health data on more than 100,000 individuals from previous large studies to determine whether genetic alterations that are associated with vitamin D levels predispose people to asthma, dermatitis, or high IgE levels.

The electrical disturbance can occur suddenly due to a heart attack, severe imbalance of electrolytes, or an inherited genetic mutation that predisposes to electric abnormalities.

DNA methylation can mimic genetic variation, predisposing a family to breast cancer.

In experiments with cancer cell lines, the PIM1 inhibitors killed cells in a MYC - dependent manner, and in two different mouse models — one in which mice were implanted with patient tumors and the other in which a genetic alteration of MYC predisposes the mice to tumor development — the administration of PIM1 inhibitors resulted in significant tumor regression.

In 2005, Ride was one of the authors of a letter to Science addressing remarks by Lawrence Summers, then - president of Harvard University, asserting that genetic differences predispose men to perform better in math and scientific fields.

They add: «What is similar between now and then is the human genetic material, our genome, including ancient polymorphisms that were uncovered to predispose the carrier to the development of atherosclerotic cardiovascular disease... however, our ancient ancestors were certainly susceptible to many other conditions, such as infectious diseases, nutritional deprivation, and trauma, which often resulted in death at an early age, before atherosclerotic heart disease had a clinical impact.»

The researchers are now examining changes in the brains of individuals who go on to develop psychotic disorders, as well as potential environmental and genetic risk factors that may predispose individuals to poor cognition.

«What happens is the genetic defect predisposes patients to infections that drive the production of mucus that then blocks the airways and makes it difficult to breath.»

UCLA researchers have discovered that certain Asian - American college students have a genetic variation that predisposes them to food addiction.

«Our genetic relatedness and close ecological connection to nonhuman primates seems to predispose us to sharing viruses — and that can happen in both directions,» he says.

Researchers from UCL (University College London) identified an epigenetic signature in the blood of women predisposed for breast cancer owing to an inherited genetic mutation of the BRCA1 gene.

Genetic studies have turned up several genes that appear to predispose for IBD, most of them involved in the body's immune response.

The researchers say this supports the «female protective effect» hypothesis because females with autism carry greater genetic load predisposing them to develop the condition, compared to males.

Jenny believes that her childhood experiences and her mother's mental health issues predisposed her to psychosis — perhaps not surprisingly, because there is a known genetic component.

For instance, one genetic variant might both predispose people to smoking and increase the risk of schizophrenia, without one causing the other.

'' [Type 1 diabetes] is clearly is one of these complex genetic disorders,» involving mutations in several genes acting in concert to predispose someone to the condition, says Hakon Hakonarson, director of The Children's Hospital of Philadelphia's Center for Applied Genomics and lead author of the new study, published this week in the online edition of Nature.

The intermediate phenotypes determine, in part, variation in disease expression and clinical presentation among individuals with equivalent underlying genetic or environmental exposures that predispose to a disease state.

Milestone in cancer genetics: a common genetic variant conferring significant risk of a common cancer in the general population Scientists at deCODE genetics (Nasdaq: DCGN) along with academic colleagues in Iceland, the US and Sweden today report the discovery of a common genetic variant that predisposes to prostate cancer.

Joslin scientists are currently investigating whether there are other genetic variants that specifically predispose type 2 diabetic subjects to cardiovascular disease and are planning to expand this research to investigate genetic variants associated with CHD in the type 1 diabetes population.

With powerful new genetic tools, Silvana Konermann plans to untangle the complex web of genes that predispose a person to Alzheimer's disease.

Last month, a new study found that roughly 70 percent of women who carry cancer - predisposing mutations in the genes BRCA1 and BRCA2 (the main genes included in genetic tests for breast cancer patients) will develop breast cancer, often in early adulthood.

An international collaboration has revealed that one common genetic risk factor predisposes the Shar - Pei dog breed not only to recurrent fever, but also to a spectrum of persistent inflammatory signs that affect the skin, joints, ears and body as a whole.

«It is well established that there is a «hyper - inflammatory phenotype» based largely on genetic factors that is of value in protecting the young from bacterial infection before they have made IgG antibodies to the bacteria they encounter; but which, in later life predisposes to the inflammatory diseases of old age.

«Dr. Tsuang's ultimate goal is to help prevent psychiatric disorders such as schizophrenia and other mental illnesses before their onset, and to identify traits that might predispose a person to developing this type of devastating illness, either because of genetic or environmental causes,» said Lewis L. Judd, M.D., Mary Gilman Marston Professor and Chair of UCSD's Department of Psychiatry.

We hope that by understanding the genetic and environmental factors that predispose to mental illnesses, and understanding the mechanisms of disorders within the brain, that we can develop new strategies to better treat, manage, and ultimately to prevent them.

This unprecedented analysis led to the discovery of the first identified common genetic variant shown to predispose Latin American populations to the disease.

A genetic mutation common in the most severe forms of muscular dystrophy also predisposes to heart damage.

In the next decade, molecular research is going to further develop along five lines: predictive medicine, that investigates the genetic conditions predisposing to tumor risk; early molecular diagnosis; the evaluation of each patient's prognosis based on his / her genetic profile, in other words, the analysis of what kind of mutation affects the DNA of altered cells; the investigation of the individual response to drugs, based on our genetic knowledge; «smart drugs», molecules able to hit the target in a selective way, killing only the deprogrammed cells.»

Although a substantial portion of risk of breast cancer is inherited, it has taken painstaking research to find genetic variants predisposing to the disease's common forms.

Though a substantial portion of risk of this common disease is clearly familial, it has proven difficult to find genetic variants predisposing to its common forms.