Sentences with phrase «predisposition to cancer»

Hereditary predisposition to cancer is sometimes due to a single high - risk genetic change, like a mutation in the BRCA1 or BRCA2 genes for breast cancer, but most of the time, the disease is the result of multiple gene variants that add up, environmental risk factors, and a big element of chance.

Speaking at a meeting on genetic predisposition to cancer at the Royal Marsden Hospital and Institute of Cancer Research, Kash said the women in the programme were as anxious about cancer as those who had already contracted and survived other cancers.

PLoS Genetics 2015, 11 (2): e1004922 To shed light on the genetic predisposition to cancers of the hematologic system, we performed genome - wide association analysis of affected and non-affected pet dogs.

He is also interested in genes induced by the interferon response, and his future plans include investigating genes identified in the expression of genome - wide association screens for predisposition to cancers.

The findings may also lead to drugs to prevent rhabdomyosarcoma in children with a genetic predisposition to the cancer, Hatley said.

The earliest ancestors of golden retrievers were chosen for their yellow coat and patient personality, but these desired traits came with an unfortunate side effect: a genetic predisposition to cancer, which ends up claiming the life of up to 63 percent of these dogs, according to one study.

Another is dyskeratosis congenita, a rare bone marrow disorder accompanied by much more serious effects such as early aging and predisposition to cancer.

«Because defects in DNA repair pathways are commonly observed in genetically inherited cancer syndromes, such as familially inherited breast cancer, it is possible that mutations in the new factors may contribute to genetic predisposition to cancers.»

And saccharin was rehabilitated as a safe additive in 1997, when scientists found that rats used in earlier studies had a predisposition to cancer unrelated to the sweetener.

Mutations in many of the genes that regulate DNA interstrand cross-link repair cause Fanconi anemia, a rare disorder that can lead to infertility, bone marrow failure, and predisposition to cancer.

«These people have a predisposition to cancer,» says Biesecker.

They said any predisposition to cancer within Tai's family could not be determined because all of his litter mates died before the age of eight — long before most cancers normally develop.

BUFFALO, N.Y. — Predisposition to cancer and cancer progression can result from gene mutations that cause elevated rates of genetic damage.

This article will concentrate on some of the common breeds and their predispositions to cancer.

Readers also learn that veterinarians love their dogs despite their breed or genetic predisposition to cancer and other conditions.

It's like stacking a deck of cards with ten extra aces and ten extra face cards; the loaded deck increases your chance of hitting blackjack in a game of 21 - but what you «win» might be allergies or a predisposition to cancer.