In the unvaccinated Group 3, 39 of 46 dogs (84 %) that relapsed were treated with salvage chemotherapy and one dog received
prednisone alone; however, only 3 (7.7 %) of the dogs in Group 3 that received salvage therapy achieved a durable second remission, compared to 40 % of vaccinated dogs that achieved a durable second remission to salvage therapy, a difference that was statistically significant (p = 0.025).
The two other dogs (one treated with COP chemotherapy and 1 treated with
prednisone alone) were euthanized at 722 and 958 days respectively; as noted above, the first dog had hemangiosarcoma and the second dog was euthanized due to «declining health.»
They are used when
prednisone alone is not sufficient.
Although researchers concluded that procarbazine and prednisone was a more effective combination than
prednisone alone, they did not actually include a group of dogs treated with
prednisone alone in this study.
With
prednisone alone, median survival times noted are approximately 75 - 90 days.
Cats with intestinal lymphoma who are treated with
prednisone alone have a life expectancy of 60 - 90 days.